A5060871701- Transcranial Magnetic Stimulation Studies
- Global Health and Surgery
- Neuroscience and Neural Engineering
- Global Health Workforce Issues
- Diversity and Career in Medicine
- Attention Deficit Hyperactivity Disorder
- Neurological disorders and treatments
- Dental Education, Practice, Research
- COVID-19 Clinical Research Studies
- COVID-19 diagnosis using AI
- Delphi Technique in Research
- Migraine and Headache Studies
- Neural and Behavioral Psychology Studies
- Health Systems, Economic Evaluations, Quality of Life
- Liver Disease and Transplantation
- RNA modifications and cancer
- Breast Cancer Treatment Studies
- RNA Research and Splicing
- Organ Transplantation Techniques and Outcomes
- Healthcare Policy and Management
- Pain Mechanisms and Treatments
- Pain Management and Treatment
- Obsessive-Compulsive Spectrum Disorders
- Surgical Sutures and Adhesives
- Pharmaceutical industry and healthcare
Tufts University
2018-2024
Tufts Medical Center
2023
University of Southern California
2023
Yale University
2023
Vanderbilt University Medical Center
2023
Lahey Hospital and Medical Center
2023
Hospital Universitario Mayor, Mederi
2022
Ahmadu Bello University
2022
Great Ormond Street Hospital
2022
University College London
2022
Transcranial direct current stimulation (tDCS) is a non-invasive brain technique that has been shown to improve common symptoms of neurological disorders like depressed mood, fatigue, motor deficits and cognitive dysfunction. tDCS requires daily treatment sessions in order be effective. We developed remotely supervised (RS-tDCS) protocol for participants with multiple sclerosis (MS) increase accessibility tDCS, reducing clinician, patient, caregiver burden. The goal this facilitate home use...
The remotely supervised tDCS (RS-tDCS) protocol enables participation from home through guided and monitored self-administration of treatment while maintaining clinical standards. current consensus regarding the efficacy is that multiple sessions are needed to observe targeted behavioral reductions in symptom burden. However, requirement for patients travel clinic daily stimulation presents a major obstacle potential participants, due work or family obligations limited ability travel. This...
Background. Sparse data documenting the impact of COVID-19 in Africa has fostered belief that skipped Africa. We previously published results from a systematic postmortem surveillance at busy inner-city morgue Lusaka, Zambia. Between June-October 2021, we detected 15-19% all deaths and concentrated community settings where testing for was absent. Yet these conclusions rested on small cohort 70 COVID-19+ individuals. Subsequently, conducted longer far larger follow-on survey using same...
Objectives To determine the prevalence of COVID-19 postmortem setting in Lusaka, Zambia. Design A systematic, study. Setting busy, inner-city morgue Lusaka. Participants We sampled a random subset all decedents who transited University Teaching Hospital morgue. posterior nasopharynx using quantitative PCR. Prevalence was weighted to account for age-specific enrolment strategies. Interventions Not applicable—this an observational Primary outcomes detections by Results were stratified...
The keystone perforator island flap (KPIF) was described almost a decade ago. However, this has only recently been recognized for its advantages in various clinical applications plastic surgery. A better understanding of the versatility KPIFs can help promote widespread adoption technique complex wounds anatomical regions.
Academic global surgery is a rapidly growing field that aims to improve access safe surgical care worldwide. However, no universally accepted competencies exist inform this developing field. A consensus-based approach, with input from diverse group of experts, needed identify essential will lead standardization in task force was set up using snowball sampling recruit broad content and context experts perioperative care. draft revised through the modified Delphi process two rounds anonymous...
Adverse childhood experiences (ACEs) exert a psychological and physiological toll that increases risk of chronic conditions, poorer social functioning, cognitive impairment in adulthood.To investigate the relationship between adversity clinical disease features multiple sclerosis (MS).Sixty-seven participants with MS completed ACE assessment neuropsychological assessments as part larger trial remediation.Adverse experience scores, measure exposure to adverse events childhood, significantly...
Abstract Background AMPAkines augment the function of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in brain to increase excitatory outputs. These drugs are known relieve persistent pain. However, their role acute pain is unknown. Furthermore, a specific molecular and anatomic target for these novel analgesics remains elusive. Methods The authors studied analgesic an AMPAkine, CX546, rat paw incision (PI) model postoperative measured effect on sensory depressive...
The remotely supervised tDCS (RS-tDCS) protocol enables participation from home through guided and monitored self-administration of treatment while maintaining clinical standards. current consensus regarding the efficacy is that multiple sessions are needed to observe targeted behavioral reductions in symptom burden. However, requirement for patients travel clinic daily stimulation presents a major obstacle potential participants, due work or family obligations limited ability travel. This...
Oncoplastic breast reduction mammoplasty (ORM) is an excellent treatment option for women with cancer and macromastia undergoing conservation therapy. Here, we aim to better understand the risks associated ORM compared standard (SRM).A retrospective chart review was performed of patients or SRM from 2015 2021. Primary outcomes included occurrence major minor postoperative complications in two groups delays adjuvant therapy (>90 days) among ORM.Women group (n = 198) were significantly older...
Recently, a new liver allocation policy called the acuity circles (AC) framework was implemented to decrease geographic disparities in transplant metrics across donor service areas. Early analyses have examined changes outcomes because of AC policy. However, perceptions among surgeons and staff regarding remain unknown.A 28-item survey sent division chiefs surgical directors transplantation United States. Questions assessed respondents' center-level satisfaction. We used Organ Procurement...
In Saccharomyces cerevisiae, the pre-mRNA leakage 39-kDa protein (ScPml39) was reported to retain unspliced prior export through nuclear pore complexes (NPCs). Pml39 homologs outside Saccharomycetaceae family are currently unknown, and mechanistic insight into function is lacking. Here we determined crystal structure of ScPml39 at 2.5 Å resolution facilitate discovery orthologs beyond Saccharomycetaceae, e.g. in Schizosaccharomyces pombe or human. The revealed integrated zf-C3HC Rsm1...
To examine the feasibility of 40 sessions tDCS treatment delivered at home through a telerehabilitation protocol.