A5018363858- Porphyrin Metabolism and Disorders
- Folate and B Vitamins Research
- Heme Oxygenase-1 and Carbon Monoxide
- Cassava research and cyanide
- Selenium in Biological Systems
- Porphyrin and Phthalocyanine Chemistry
- Advanced oxidation water treatment
- Methemoglobinemia and Tumor Lysis Syndrome
- Organoselenium and organotellurium chemistry
- Vitamin C and Antioxidants Research
- Metal-Catalyzed Oxygenation Mechanisms
- Sulfur Compounds in Biology
- Redox biology and oxidative stress
- Mercury impact and mitigation studies
- Magnetism in coordination complexes
- Solid-state spectroscopy and crystallography
- Trace Elements in Health
- Arsenic contamination and mitigation
- Alcohol Consumption and Health Effects
- Electrochemical sensors and biosensors
- Computational Drug Discovery Methods
- Pharmacological Effects of Natural Compounds
- Advanced Memory and Neural Computing
- Photochemistry and Electron Transfer Studies
- Molecular Spectroscopy and Structure
Ivanovo State University of Chemistry and Technology
2015-2024
Ivanovo State University
2016-2021
Friedrich-Alexander-Universität Erlangen-Nürnberg
2014
University of Chemistry and Technology, Prague
2013
The review discusses the latest advances in directed synthesis and application of macroheterocyclic compounds science, engineering technology, viz.as catalysts for various processes photo-and electrocatalysis, optical chemosensors metal cations, selective receptors organic compounds, inductors selectors, nonlinear optics, electronics, as magnets, photosensitizers PDT a number oncological diseases antimicrobial PDT, etc.
Abstract A detailed kinetic study of the reaction aquacobalamin [H 2 OCbl(III)] with hydrogen sulfide in water at pH 1 to 10 was carried out using conventional spectrophotometric, stopped‐flow, and high‐pressure stopped‐flow techniques. The proceeds three steps: formation complex between sulfide, inner‐sphere electron transfer, addition a second molecule reduced cobalamin. Kinetic parameters for different steps studied process were determined. final products found depend on pH. main product...
We studied the kinetics of reactions cob(I)alamin and cob(I)inamide with thiosulfate, sulfite, dithionite by UV-Visible (UV-Vis) stopped-flow spectroscopy. found that two Co(I) species were oxidized these sulfur-containing compounds to Co(II) forms: oxidation excess thiosulfate leads penta-coordinate complexes sulfite or hexa-coordinate Co(II)–SO2− complexes. The net scheme involves transfer three electrons in case one electron for dithionite. On basis kinetic data, nature reactive oxidants...
A nitrido-bridged iron phthalocyanine has recently been shown to catalyze hydrocarbon activation, displaying in this respect distinctly different reactivity than the monomeric or oxo-bridged dimer. Here, DFT calculations are on models of catalyst, indicating a distinct difference electronic structures between μ-oxo and μ-nitrido-bridged dimers, with nitride acting as remarkable charge reservoir acquiring S = 1 N-character while oxo bridge remains redox-inert; localization appears be mirrored...
Recently, we have described the first supermolecular nanoentities (SMEs) of a vitamin B12 derivative, viz., monocyano form heptabutyl cobyrinate ((CN–)BuCby), unique nanoparticles with strong noncovalent intermolecular interactions, and emerging optical redox properties. In this work, fast response thin films based on SMEs derivative to gaseous toxins (viz., hydrogen cyanide, ammonia, sulfur dioxide, sulfide) particularly dangerous for humans was demonstrated. The reaction between (CN–)BuCby...
Medicinal effects of hydrophobic derivatives vitamin [Formula: see text] have been insignificantly investigated primarily due to their low solubility in aqueous solutions. One the ways increase water is complexation with proteins. Here, we report results studies reactions between aquacyano cobyrinic acid or monocyano cobesters (i.e., heptamethyl, heptaethyl, heptapropyl, and heptabutyl cobyrinates) bovine serum albumin (BSA). The weakest binding observed BSA. In case heptaethyl cobyrinate,...
Background. Chemical derivatives of vitamin B12 are characterized by a wide range pharmacological effects. It is important to learn how establish relationships between changes the corrin ring structure in and properties. Objective: evaluate interaction six (aquacobalamin, diaquacobinamide, aquacyano-forms heptaethanolamine, heptaethylenediamine, heptamethyl heptabutyl cobyrinates) with human proteome proteins. Material methods. Using method chemoinformational (chemoproteomic) analysis,...
Here, we report the results of investigation reactions between brominated and chlorinated at C10 position corrin cyano- (CNCbl-Hal, Hal = Br, Cl) aquacobalamins (H 2 OCbl-Hal) Angeli’s salt (AS). The involving H OCbl-Hal AS proceed via two parallel routes, i.e., or HOCbl-Hal HNO generated upon decomposition AS, generate corresponding nitrosylcobalamins (NOCbl-Hal). In contrast to process unmodified CNCbl, CNCbl-Hal can be used produce NOCbl-Hal, which explained by labilization axial...
One of the most attractive molecular systems in world chemistry and medicine is vitamin B12, which was originally discovered as a factor against deficiency (pernicious) anemia. Deficiency this essential leads to decrease number red blood cells drop hemoglobin levels. The article provides brief overview processes leading destruction B12 caused by hypoxia, action hypochlorous acid, superoxide anion radical, hydrogen peroxide, hydroxyl peroxynitrite. Under conditions oxygen transport electron...
Kinetics of cobinamide (Cbi) reduction by glucose and fructose was studied at alkaline solutions.It shown that the reaction with monosaccharides leads to formation Co(I) complex in contrast aquacobalamin (H 2 OCbl) resulting Cbl(II).
This study reports that aquahydroxocobinamide [(H 2 O)(HO – )Cbi(III)], a nucleotide‐free analogue of cobalamin (vitamin B 12 ; Cbl), is capable catalyzing the reduction two‐electron oxidized form vitamin C, dehydroascorbic acid (DHA), to ascorbic by glutathione (GSH), whereas catalytic quantities aquacobalamin do not accelerate reaction. observation explained different reactions taking place with Co III ‐species these complexes and GSH: Cbl(III) forms stable complex GSH, but Cbi(III)...