- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Cancer and Skin Lesions
- Breast Implant and Reconstruction
- Cancer Cells and Metastasis
- Cancer Genomics and Diagnostics
- HER2/EGFR in Cancer Research
- Global Cancer Incidence and Screening
- Cancer Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- AI in cancer detection
- Colorectal and Anal Carcinomas
- Male Breast Health Studies
- Genetic factors in colorectal cancer
- Radiomics and Machine Learning in Medical Imaging
- BRCA gene mutations in cancer
- Cutaneous Melanoma Detection and Management
- Salivary Gland Tumors Diagnosis and Treatment
- Advanced Breast Cancer Therapies
- Cancer Risks and Factors
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Cancer Immunotherapy and Biomarkers
University of Szeged
2016-2025
Bács-Kiskun Megyei Kórház
2015-2024
St. Antonius Ziekenhuis
2010
The Netherlands Cancer Institute
2010
University Medical Center Utrecht
2010
Sichuan University
2010
West China Hospital of Sichuan University
2010
Universidade Federal do Rio de Janeiro
2010
University of Pennsylvania
2010
Institute of Cancer Research
2010
Histopathology is a cornerstone in the diagnosis of cervical cancer but prognostic value controversial.Women under active follow-up for histologically confirmed primary invasive were selected from United States Surveillance, Epidemiology, and End Results (SEER) 9-registries public use data 1973-2002. Only histologies with at least 100 cases retained. Registry area, age, marital status, race, year diagnosis, tumor histology, grade, stage, size, number positive nodes, examined odds nodal...
To evaluate aspects of the current practice sentinel lymph node (SLN) pathology in breast cancer via a questionnaire based survey, to recognise major issues that European guidelines for mammography screening should address next revision.A was circulated by mail or electronically authors their respective countries. Replies from units dealing with SLN specimens were evaluated further.Of 382 respondents, 240 specimens. Sixty per cent these carried out intraoperative assessment, most commonly...
The number of lymph nodes found to be involved in an axillary dissection is among the most powerful prognostic factors breast cancer, but it confounded by that have been examined. We investigate idea has surfaced recently literature (since 1999), namely proportion node-positive (or a function thereof) much better predictor survival than excised and nodes, alone or together.The data were abstracted from 83,686 cases registered Surveillance, Epidemiology, End Results (SEER) program women...
Because of the existing controversy, we searched for a cutoff value number lymph nodes (LNs) to be examined in order establish reliable node-negative stage colorectal carcinomas (CRCs).From SEER database, 8,574 T3N0M0 first, single, histologically confirmed, surgically treated CRCs, with at least 1 LN histologically, were considered. As first approach, relationships between LNs and 5- 10-year overall survival (OS) rates, computed by Kaplan-Meier method, assessed. Next, multivariate analysis...
The latest edition of the tumor-lymph node-metastasis (TNM) classification malignant tumors distinguishes between isolated tumor cells (pN0) and micrometastases (pN1mi). reproducibility these categories has not been assessed previously.Digital images from 50 cases with low-volume lymph node involvement axillary sentinel nodes were circulated twice for evaluation (Evaluation Rounds 1 2) among members European Working Group Breast Screening Pathology, asked to categorize lesions as...
BackgroundAxillary treatment of breast cancer patients is undergoing a paradigm shift, as completion axillary lymph node dissections (ALNDs) are being questioned in the with tumor-positive sentinel nodes. This study aims to develop novel multi-institutional predictive tool calculate patient-specific risk residual disease after biopsy.
BackgroundBased on its mechanism of action, PARP inhibitor therapy is expected to benefit mainly tumor cases with homologous recombination deficiency (HRD). Therefore, identification types increased HRD important for the optimal use this class therapeutic agents. levels can be estimated using various mutational signatures from next generation sequencing data and we used approach determine whether breast cancer brain metastases show altered scores relative their corresponding primary...
Abstract Male breast cancer (MBC) is rare. We assembled 446 MBCs on tissue microarrays and assessed clinicopathological information, together with data from 15 published studies, totalling 1984 cases. By immunohistochemistry we investigated 14 biomarkers (ERα, ERβ1, ERβ2, ERβ5, PR, AR, Bcl-2, HER2, p53, E-cadherin, Ki67, survivin, prolactin, FOXA1) for survival impact. The main histological subtype in our cohort combined analyses was ductal (81%, 83%), grade 2; (40%, 44%), respectively....
Thirteen cases of invasive solid papillary breast carcinomas resembling the tall cell variant thyroid neoplasms (BPTC) are reported here. Some had long-term follow-up. BPTC is a special type primary neoplasm showing triple-negative profile but low aggressive potential. Knowledge on still scanty; therefore, aim present paper was to report features an additional 13 cases. All patients were female individuals, and mean age at presentation 62.6 years; nodule sizes ranged from 0.6 2.5 cm...
To assess the value of intensive histological work up axillary sentinel lymph nodes (SLN) to demonstrate regional metastatic disease.From a series 58 successful lymphatic mapping procedures, 78 SLN were analysed by serial sections (mean 49 levels/SLN) and immunostaining cytokeratin epithelial membrane antigen, results compared with those obtained assessing central cross section.The section would have failed detect metastases in eight 26 (31%) patients breast cancer metastasising only. This...
Purpose Reliable pathologic stage classification of axillary lymph nodes is an important determinant prognosis and therapeutic decision making for patients with invasive breast cancer. Pathologists' distinction between micrometastasis (pN1mi) isolated tumor cells [ITC; pN0(i+)] variable using the American Joint Committee on Cancer (AJCC) Staging Manual (Sixth Edition). We sought to determine whether a set clearly defined histologic criteria could lead reproducible nodal by pathologists....