A5028817252- Hip and Femur Fractures
- Bone fractures and treatments
- Bone health and osteoporosis research
- Pelvic and Acetabular Injuries
- Scoliosis diagnosis and treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Bacterial Identification and Susceptibility Testing
- Trauma and Emergency Care Studies
- Spinal Fractures and Fixation Techniques
- Hip disorders and treatments
- Spine and Intervertebral Disc Pathology
- Total Knee Arthroplasty Outcomes
- Connective tissue disorders research
- Musculoskeletal pain and rehabilitation
- Shoulder Injury and Treatment
- Orthopaedic implants and arthroplasty
- Urinary Tract Infections Management
- Orthopedic Surgery and Rehabilitation
- Enhanced Recovery After Surgery
- Osteoarthritis Treatment and Mechanisms
- Bone health and treatments
- Orthopedic Infections and Treatments
- COVID-19 and healthcare impacts
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Surgical Simulation and Training
University of Hong Kong
1985-2025
University of Hong Kong - Shenzhen Hospital
2024-2025
Chinese University of Hong Kong
2006-2024
Queen Mary Hospital
1985-2024
Duchess of Kent Children's Hospital
2024
Kowloon Hospital
2024
Prince of Wales Hospital
2006-2019
Severe acute respiratory syndrome (SARS) is a virulent viral infection that affects number of organs and systems. This study examined if SARS may result in cardiovascular complications.121 patients (37.5 (SD13.2) years, 36% male) diagnosed to have were assessed continuously for blood pressure, pulse, temperature during their stay hospital. Hypotension occurred 61 (50.4%) hospital, was found 28.1%, 21.5%, 14.8% the first, second, third week, respectively. Only one patient who had transient...
Coronavirus disease 2019 (COVID-19) has caused substantial disruptions to orthopaedic and trauma services. The purpose of the present study was quantify its impact on surgical volume, hospitalizations, clinic appointments, accident emergency attendances guide staffing resource deployment for sustenance services.Data were retrieved from all 43 Hong Kong public hospitals 122 outpatient clinics a population 7.5 million residents. "COVID-19 cohort" patients who received treatment January 25...
Background The analgesic effect of adding liposomal bupivacaine to standard in supraclavicular brachial plexus block is not known. authors hypothesized that addition would reduce acute postoperative pain compared alone. Methods A randomized controlled trial was conducted. Patients and outcome assessors were blinded. Eighty patients undergoing distal radial fracture fixation during regional anesthesia with into two groups. group received 10 ml 0.5% plain immediately followed by 1.33% (n =...
Osteogenesis imperfecta (OI) Type V is typically characterized by radial head dislocation, calcification of interosseous membrane and hyperplastic callus. It caused the c.-14C > T mutation in 5' UTR IFITM5 gene, adding five amino acids (MALEP) to N-terminal protein. Previous studies have suggested a neomorphic function MALEP-IFITM5 However, underlying mechanisms remain unclear due embryonic lethality previous mouse models. Therefore, we developed an inducible model (Ifitm5flox T) that could...
Background: We report changes in the natural history of hip instability with nusinersen treatment among patients spinal muscular atrophy (SMA) type II after onset weakness, historically wheelchair-bound but now potentially ambulatory era disease-modifying therapy. Methods: Patients genetically confirmed diagnoses SMA who received intrathecal from January 1, 2018, to June 30, 2022, were screened for inclusion. less than 6 months follow-up, or prior surgeries excluded. Primary clinical outcome...
Abstract Background The intermittent Pringle manoeuvre (IPM) is commonly applied during liver resection. Few randomized trials have addressed its effectiveness in reducing blood loss and the results been conflicting. present study investigated hypothesis that IPM could reduce resection by 50 per cent. Methods Between May 2008 April 2011, patients who underwent elective open hepatectomy were into an or no (NPM) group stratified according to presence absence of cirrhosis. Data on demographics,...
For growing patients, it is ideal to have a growth plate visible in routine radiographs for skeletal maturity assessment without additional radiation. The proximal femoral epiphyseal ossification proximity the spine; however, whether can be used assessing patient's status remains unknown.Two hundred and twenty sets of spine left hand wrist patients with idiopathic scoliosis were assessed reliability testing. Risser staging, Sanders staging (SS), distal radius ulna (DRU) classification,...
The Proximal Femur Maturity Index (PFMI) can be used to assess skeletal maturity on existing whole-spine radiographs without additional radiation. However, the relationship between PFMI at initiation of bracing for adolescent idiopathic scoliosis (AIS) and subsequent curve progression remains unknown. This study aimed investigate progression, predictability risks adulthood surgical thresholds based grade brace initiation.
Emerging evidence showed that bone metabolism and cardiovascular disease (CVD) are closely related. We previously observed a potential immediate risk of mortality after hip fracture. However, whether there is an events fracture unclear. The aim this study was to evaluate the for major adverse (MACEs) between patients having experienced falls with without fracture.This retrospective population-based cohort used data from centralized electronic health record database managed by Hong Kong...
Abstract Osteogenesis imperfecta (OI) is a group of severe genetic bone disorders characterized by congenital low mass, deformity, and frequent fractures. Type XV OI moderate to form skeletal dysplasia caused WNT1 variants. In this cohort study from southern China, we summarized the clinical phenotypes patients with variants found that proportion type was around 10.3% (25 out 243) diverse spectrum phenotypes. Functional assays indicated significantly impaired its secretion effective...
Patients with developmental dysplasia of the hip (DDH) are at risk for residual acetabular even after successful closed reduction. The aim this study was to identify predictors long-term outcomes in order guide prognostication and management.
Background: Long-term data on postoperative neurological survivorship for patients with degenerative cervical myelopathy (DCM) undergoing decompressive surgery are limited. The purposes of this study were to assess after primary DCM and identify predictors deterioration. Methods: A longitudinal clinical set containing surgical details, medical comorbidities, radiographic features was assembled 195 who underwent a procedure between 1999 2020, mean period observation 75.9 months. Kaplan-Meier...
Atypical femoral fractures (AFFs) are associated with delayed union and higher reoperation rates. Axial dynamization of intramedullary nails is hypothesized to reduce time-to-union (TTU) fixation failure as compared static locking.Consecutive acutely displaced AFFs fixed long across five centres between 2006 2021 a minimum postoperative follow-up three months were retrospectively reviewed. The primary outcome was TTU, treated dynamically or statically locked nails. Fracture defined modified...
Abstract Background Although back pain may be present in subjects with adolescent idiopathic scoliosis (AIS), its natural history is unknown. Therefore, this study evaluated the incidence of scoliotic adolescents longitudinally. Methods This retrospective analysis examined prospectively collected subscale data Scoliosis Research Society questionnaire between initial presentation and up to 3 years follow-up. Consecutive AIS aged 10–18 at baseline managed by observation within period were...