A5038702566- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Cardiac Valve Diseases and Treatments
- Renal Transplantation Outcomes and Treatments
- Cardiac Arrest and Resuscitation
- Fuel Cells and Related Materials
- Aortic Disease and Treatment Approaches
- Organ Transplantation Techniques and Outcomes
- Cardiac and Coronary Surgery Techniques
- Cardiac pacing and defibrillation studies
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Viral Infections and Immunology Research
- Heart Failure Treatment and Management
- Membrane-based Ion Separation Techniques
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Issues in Pregnancy
- Electron and X-Ray Spectroscopy Techniques
- Molecular Junctions and Nanostructures
- HIV/AIDS drug development and treatment
- Intensive Care Unit Cognitive Disorders
- Peptidase Inhibition and Analysis
- Pneumocystis jirovecii pneumonia detection and treatment
- Organ Donation and Transplantation
Medical University of Vienna
2013-2022
Ludwig Boltzmann Cluster for Cardiovascular Research
2017
University of California, San Francisco
2017
Vienna General Hospital
2017
Saint Luke's Hospital
2016
Universitätsklinik für Chirurgie Wien
2013
San Diego Cardiac Center
2013
Background— Left ventricular assist device–supported patients are usually anticoagulated with a combination of aspirin and vitamin K antagonists. Long-term antagonist therapy can be complicated by unstable international normalized ratio values patient-related compliance problems. Therefore, direct thrombin inhibitors may represent an alternative to Methods Results— Thirty HeartWare device stable renal function were planned for this prospective, randomized, open-label, single-center study....
Avoiding full sternotomy and cardiopulmonary bypass (CPB) could significantly reduce the invasiveness of left ventricular assist device (LVAD) implantation. Therefore, we developed minimally invasive implant strategies for Heartware® VAD (HVAD) Thoratec® HeartMate II (HMII) covering isolated LVAD implantation as well concomitant valve procedures (aortic/tricuspid). We present surgical techniques initial clinical experience.From February 2012 to March 2013, 27 patients (mean age 58 ± 8 years;...
Interagency Registry for Mechanical Assisted Circulatory Support (INTERMACS) Level I patients have the highest early mortality after ventricular assist device (VAD) implantation. This is determined by exposure of in shock with acutely damaged end-organs and high catecholamine support to a significant surgical trauma. We report our experience bridge-to-bridge concept consisting initial veno-arterial extracorporeal life (ECLS) deferral VAD implantation recovery end-organ function INTERMACS...
The implantation of rapid-deployment aortic valves may interfere with the conduction system heart. This study evaluates occurrence and predictive factors anomalies in patients undergoing surgical valve replacement (SAVR) a balloon-expandable bioprosthesis single-center, real-world experience.Between May 2010 April 2019, 700 consecutive were included prospective, ongoing database longitudinal follow-up preoperatively, at discharge, 3 months, 1 year, years, 5 years postoperatively....
The Edwards Intuity Valve System is a bioprosthesis with balloon-expandable stent frame which enables rapid-deployment (RD). We aimed to analyze our single-center long-term experience follow-up until 9 years after aortic valve replacement (AVR) this bioprosthesis.Between May 2010 and 2019, 700 consecutive patients severe stenosis or combined disease, implanted RD at institution, were included in prospective database. Median was 19 months the total accumulated 2,140 patient-years....
The aim was to evaluate the association of molecular-level human leukocyte antigen (HLA) mismatching with post-transplant graft survival, rejection, and cardiac allograft vasculopathy (CAV). We retrospectively analyzed all primary transplant recipients between 01/1984-06/2016. 1167 patients fulfilled inclusion criteria had HLA typing information available. In 312 donor-recipient pairs, at serological split level used Epitope MisMatch Algorithm calculate number amino acid differences in...
Right ventricular (RV) failure complicating left assist device implantation is associated with increased mortality. Despite a lack of supporting evidence, venoarterial extracorporeal membrane oxygenation (ECMO) support increasingly being used as an alternative to traditional temporary RV support. We report our institutional experience ECMO-facilitated after implantation.We retrospectively reviewed the concept ECMO for perioperative in 32 consecutive (mean age 52 ± 14 years; male 84.4%;...
Abstract OBJECTIVES Although extracorporeal membrane oxygenation (ECMO) represents a rapidly evolving treatment option in patients with refractory heart or lung failure, survival remains poor and appropriate risk stratification challenging because established prediction models have not been validated for this specific population. METHODS This observational single-centre registry included total of 240 treated venoarterial ECMO therapy following cardiovascular surgery analysed the...
BackgroundVenoarterial-extracorporeal membrane oxygenation (VA-ECMO) is a life-saving method for patients with low-output failure after cardiac surgery. However, VA-ECMO therapy may increase left ventricular afterload due to retrograde blood flow in the aorta, which lead progression of pulmonary congestion. We examined predictive value congestion that need support cardiovascular surgery.MethodsWe enrolled total 266 adult undergoing following surgery at university-affiliated tertiary care...
Abstract With increasing support duration of cardiac assist devices, transcutaneous drivelines remain a weak point the therapy. First, they can be an entry for infections, and second, cable lesions even electrical failures due to material fatigue eventual carelessness occur. We report case damaged outer sheath ventricular device driveline directly at exit site, where standard repair procedure with self‐fusing tape may lead biocompatibility problems irritation entrance through skin....
Left ventricular assist device outflow graft stenosis is a rare but life-threatening complication of mechanical cirulatory support therapy. Current treatment modalities (pump exchange or systemic thrombolytic therapy) are associated with significant mortality and morbidity. Implantation bare metal stents within the stenosed an alternative. Herein, we describe series three cases successful stent placement. This seems to be safe successful; however, correct early diagnosis can challenging....
New left ventricular assist devices (LVADs) offer both important advantages and potential hazards. VAD development requires better expeditious ways to identify these We validated in an isolated working heart the hemodynamic performance of intraventricular LVAD investigated how its outflow cannula interacted with aortic valve. Hearts from six pigs were explanted connected setup. A miniaturized was implanted within ventricle (tMVAD, HeartWare Inc., Miami Lakes, FL, USA). In four experiments...
The era of intracorporal continuous flow pumps has initiated significant success left ventricular assist device (LVAD) surgery. However, median sternotomy been the only surgical approach for implantation over many years. During last decade, less-invasive access ways gained popularity. Within this review, we describe our own clinical experience in minimally invasive (VAD) surgery and summarize current scientific literature on topic.