A5081541155- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Glaucoma and retinal disorders
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Ocular Surface and Contact Lens
- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Artificial Intelligence in Healthcare and Education
- Nanoparticle-Based Drug Delivery
- Autopsy Techniques and Outcomes
- Advanced Drug Delivery Systems
- Medical Malpractice and Liability Issues
- Retinal Imaging and Analysis
- Ocular Infections and Treatments
- Ocular Oncology and Treatments
- CNS Lymphoma Diagnosis and Treatment
- Inhalation and Respiratory Drug Delivery
- Abdominal Surgery and Complications
- Optical Coherence Tomography Applications
- Laser Applications in Dentistry and Medicine
- COVID-19 Clinical Research Studies
- Folate and B Vitamins Research
- Retinal and Macular Surgery
- Curcumin's Biomedical Applications
Magna Graecia University
2012-2025
Polytechnic University of Turin
2024
May Institute
2017
Moria (France)
2015
Accredited Private Hospital Villa Regina
2015
Fundación Juan March
2015
Veneto Eye Bank Foundation
2014
Interventi Geo Ambientali (Italy)
2012
Photobiomodulation (PBM) has become a promising approach for slowing the progression of early and intermediate dry age-related macular degeneration (dAMD) to advanced AMD. This technique uses light penetrate tissues activate molecules that influence biochemical reactions cellular metabolism. preliminary analysis is aimed at assessing safety, tolerability, short-term effectiveness EYE-LIGHT
Aims/Purpose: This case report aims to describe the posterior lamellar approach manage stromal interface irregularity after deep anterior keratoplasty (DALK). Methods: A 42‐year‐old woman previously underwent DALK with visco‐bubble failed for keratoconus associated intraoperative perforation. One year surgery, she presented our center loss visual acuity. The recipient bed appeared wrinkled and opaque. optical surface was regular, low regular astigmatism. Endothelial cell density (ECD) could...
Aims/Purpose: Recently, our group demonstrated how the Large Language Model GPT‐4 can fabricate fake ophthalmology data sets, designed to support false scientific evidence. The objectives of this study were: (1) identify peculiar statistical patterns AI‐generated (2) attempt at enhancing quality fabricated for eliminating any discernible mark non‐authenticity, and (3) develop a custom GPT trained detect signs fabrication. Methods: Three fictional studies were compare treatment outcomes...
Aims/Purpose: Recently, our group demonstrated how the Large Language Model GPT‐4 can fabricate fake ophthalmology data sets, designed to support false scientific evidence. The objectives of this study were: (1) identify peculiar statistical patterns AI‐generated (2) attempt at enhancing quality fabricated for eliminating any discernible mark non‐authenticity, and (3) develop a custom GPT trained detect signs fabrication. Methods: Three fictional studies were compare treatment outcomes...
Aims/Purpose: To analyze how postoperative outcomes of manual deep anterior lamellar keratoplasty (DALK) are influenced by the thickness residual stromal bed recipient, and to explore predictive factors for this parameter. Methods: This is a retrospective case series patients affected keratoconus undergone DALK. Best spectacle‐corrected visual acuity (BSCVA) tomographic parameters were evaluated preoperatively (T0) postoperatively after complete suture removal (1 year, T1). The recipient at...
The aim of this study was to report the successful clinical outcome recalcitrant neurotrophic keratopathy (NK) treated with insulin eye drops associated therapeutic Hyper-CL soft contact lens (CL) (EyeYon Medical, Ness Ziona, Israel).This is a case report.A 40-year-old man referred our clinic for management severe NK developed after surgical and adjuvant radiotherapy treatment adenoid cystic carcinoma nasal cavity basicranial involvement. patient presented conjunctival hyperemia, large (7 ×...
To describe the clinical outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) in a series patients affected by progressive cell loss leading to corneal decompensation with membrane (DM) breaks caused obstetrical forceps trauma.Seven amblyopic eyes 7 unilateral visual due increasing edema were included study. In all eyes, slit-lamp examination revealed typical DM and diffuse edema: these findings compatible history forceps-assisted delivery. DSAEK was performed cases (in...
To report the results of a modified big-bubble deep anterior lamellar keratoplasty technique using intraoperative red reflex to visualize amount residual stroma beneath inserted cannula.A total 132 consecutive keratoconic eyes were included in this retrospective, noncomparative, interventional case series. Before starting surgery, pharmacologic mydriasis was induced all undergoing procedure. After partial trephination recipient cornea, spatula at base incision and advanced into depth as...
Abstract Context: The rapid growth and diversification of drug delivery systems have been significantly supported by advancements in micro- nano-technologies, alongside the adoption biodegradable polymeric materials like poly(lactic-co-glycolic acid) (PLGA) as microcarriers. These developments aim to reduce toxicity enhance target specificity delivery. use silico methods, particularly molecular dynamics (MD) simulations, has emerged a pivotal tool for predicting species within these systems....
Aims To evaluate deep corneal densitometry and visual outcomes after big-bubble (BB-DALK) visco-bubble (VB-DALK) anterior lamellar keratoplasty performed in patients with keratoconus. Methods Prospective comparative study of 50 advanced keratoconic who underwent DALK surgery; 25 eyes (group I) were completed BB-DALK II) VB-DALK the failure pneumatic dissection. Best spectacle-corrected acuity (BSCVA), tomographic parameters endothelial cell count recorded 1, 3, 6, 12 24 months surgery....
We describe the use of a simple tool to evaluate postoperative alignment toric intraocular lenses (IOLs). The entire anterior segment is scanned using optical coherence tomography and analyzed with an internal dedicated tool. A topographic map displayed along image, including linear axis marker centered on corneal apex. can be rotated until it aligned line connecting IOL marking dots, precisely reproducing astigmatic axis, which measured in angle degrees. value compared shown real time same...
Aim To report the outcomes of bubble formation obtained by means intrastromal injection ophthalmic viscoelastic device (OVD) after failure pneumatic dissection for deep anterior lamellar keratoplasty (DALK). Methods DALK was performed in 140 keratoconic eyes 130 patients injecting air and OVD only secondarily, had failed; rates were recorded; complications, best spectacle-corrected visual acuity (BSCVA) corneal tomographic parameters evaluated 3 months, 6 months 12 postoperatively, as well...
To evaluate the feasibility and initial outcomes of a novel standardized surgical technique femtosecond laser- (FSL-) assisted big-bubble deep anterior lamellar keratoplasty (BBDALK) for eyes with keratoconus.This prospective interventional case series included 11 consecutive FSL-assisted BBDALK procedures performed keratoconus from September 2019 to December 2019. The FSL was used create (i) an intrastromal channel incision (1.7 mm in length, 4.6 width, 80% depth, cut energy 1.70 μJ) (ii)...
Purpose: The purpose of the study was to compare clinical outcomes large 9.0-mm diameter and conventional 8.0-mm big-bubble deep anterior lamellar keratoplasty (DALK). Methods: In this comparative, retrospective interventional case series, medical records 124 cases DALK from January 2017 December 2019 133 2014 2016 performed by a single surgeon for indication keratoconus were reviewed. Main outcome measures best spectacle-corrected visual acuity (BSCVA), refractive astigmatism (RA),...
Ocular complications can occur in up to 90% of patients with blood malignancies. Such range from direct infiltration local hemostatic imbalance and treatment-related toxicity. This narrative review is based on a systematic computerized search the literature conducted until January 2024 examines common ocular associated cancers. primary disease include mass effects adnexal lymphomas intraocular lymphomas, B-cell accounting for 95% presentations. Secondary involvement systemic hematological...
Introduction Central Serous Chorioretinopathy (CSC), a leading cause of vision loss, presents diverse treatment challenges based on its acute or chronic manifestation.
We present the case of a 57-year-old woman who had combined Descemet-stripping automated endothelial keratoplasty (DSAEK) and phacoemulsification with implantation toric intraocular lens (IOL). Surgery was intended to treat cataract developing in post-penetrating (PKP) eye high astigmatism decompensation. Six months after uneventful surgery, cornea clear corrected distance visual acuity 20/20 refraction +0.25 −1.00 × 10 (from −3.00 −8.50 12 preoperatively). The internal topography map...
The purpose of this study was to evaluate the incidence, timing and risk factors corneal neovascularisation (NV) after deep anterior lamellar keratoplasty (DALK) for ectasia.This included 616 eyes who underwent DALK between 2012 2020 in two tertiary referral centres. In one centre topical corticosteroids were discontinued complete suture removal 1 year surgery, whereas other they 3-4 months surgery. presence severity NV ascertained based on slit lamp photographs. Potential evaluated using...
The aim of this study was to describe a surgical technique for repeat deep anterior lamellar keratoplasty (DALK) by baring Descemet membrane again in eyes affected stromal opacity the donor lamella.Repeat DALK performed 5 patients central not involving endothelium; indications surgery were postbacterial or postherpetic corneal scars (n = 3), postphotorefractive keratectomy haze 1), and recurrence granular dystrophy 1). procedure consisted following: (1) superficial trephination, 250 μm...
Purpose To evaluate the outcomes of deep anterior lamellar keratoplasty (DALK) followed by phacoemulsification and toric intraocular lens (IOL) implantation for treatment concomitant stromal disease cataract. Methods In this retrospective non-comparative interventional case series, ten eyes affected cataract underwent DALK with IOL after a minimum period 5 months from complete suture removal. each case, topographic astigmatism, refraction, visual acuity, endothelial cell density were...
Purpose: To compare visual outcomes of two newly developed monofocal intraocular lenses (IOLs) (I-Stream H and CT Lucia 211P) implanted in patients undergoing surgery for senile cataract. Methods: This prospective, comparative, single-center, randomized study included 94 eyes cataract surgery. Patients were to receive the implantation I-Stream IOL (Group 1) or 211P 2). Each patient underwent a complete ocular examination before (V0), 1 month (V1), 3 months (V2) 6 (V3) after surgery,...