A5044076155- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Lung Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Advanced X-ray and CT Imaging
- Colorectal and Anal Carcinomas
- Medical Imaging Techniques and Applications
- Liver Disease Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Gastrointestinal disorders and treatments
- Bone and Joint Diseases
- Renal cell carcinoma treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Rheumatoid Arthritis Research and Therapies
- Endometrial and Cervical Cancer Treatments
- Cancer Immunotherapy and Biomarkers
- Sarcoma Diagnosis and Treatment
- Medical Imaging and Analysis
- Cardiac Imaging and Diagnostics
- Gastrointestinal Tumor Research and Treatment
- Renal and related cancers
- Pancreatitis Pathology and Treatment
- Pelvic and Acetabular Injuries
- Osteoarthritis Treatment and Mechanisms
- Medical Imaging and Pathology Studies
Jinan University
2015-2025
Southern University of Science and Technology
2020-2025
ShenZhen People’s Hospital
2002-2024
Shenzhen Second People's Hospital
2024
Brown University
2024
Air Force Medical University
2023
Xijing Hospital
2023
University of California, San Francisco
2016-2017
Laboratoire d’Imagerie Biomédicale
2017
University of California System
2016
To investigate whether radiomic features can be surrogate biomarkers for epidermal growth factor receptor (EGFR) mutation statuses. Two hundred ninety six consecutive patients, who underwent CT examinations before operation within 3 months and had EGFR mutations tested, were enrolled in this retrospective study. texture extracted using an open-source software with whole volume segmentation. The association between statuses analyzed. In the 296 there 151 patients (51%). Logistic analysis...
Background Lymphovascular space invasion (LVSI) of endometrial carcinoma (EMC) is one the important prognostic factors, which not usually visible subjectively. Therefore, clinicians lack imaging‐based evidence about LVSI for preoperative treatment decision‐making. Purpose To develop a multiparametric MRI (mpMRI)‐based radiomics nomogram predicting in EMC and provide decision‐making support to clinicians. Study Type Retrospective. Population In all, 144 patients with histologically confirmed...
Lymphovascular space invasion (LVSI) is associated with lymph node metastasis and poor prognosis in cervical cancer. In this study, we investigated the potential of radiomics, derived from magnetic resonance (MR) images using habitat analysis, as a non-invasive surrogate biomarker for predicting LVSI cancer.This retrospective study included 300 patients cancer who underwent surgical treatment at two centres (centre 1 = 198 centre 2 102). Using k-means clustering method, contrast-enhanced...
Due to the presence of distinctive morphological features and diverse pathological types, evaluation breast non-mass enhancement (NME) lesions on magnetic resonance imaging (MRI) is challenging, generating more false-positive results as compared enhancing mass lesions. Our objective was identify MRI capable distinguishing between benign malignant NME in breast. A retrospective analysis conducted, which clinical data manifestations 101 were examined confirmed through surgical or biopsy...
Programmed cell death ligand 1 (PD-L1), as a reliable predictive biomarker, plays an important role in guiding immunotherapy of lung cancer. To investigate the value CT-based deep learning radiomics signature to predict PD-L1 expression non-small cancers(NSCLCs). 259 consecutive patients with pathological confirmed NSCLCs were retrospectively collected and divided into training cohort validation according chronological order. The univariate multivariate analyses used build clinical model....
Solitary pulmonary nodule (SPN) is defined as a rounded opacity ≤3 cm in diameter surrounded by lung parenchyma. The majority of smokers who undergo thin-section CT have SPNs, most which are smaller than 7 mm. In the past, multiple follow-up examinations over two-year period, including at 3, 6, 12, 18, and 24 months, were recommended when such nodules detected incidentally. This policy increases radiation burden for affected population. Nodule features shape, edge characteristics,...
Background: To evaluate the longitudinal changes of bone marrow edema-like lesions (BMELs) in patients after anterior cruciate ligament (ACL) reconstruction and to investigate effect BMELs on cartilage matrix composition measured using MR T1ρ T2 mapping. Methods: Patients with acute ACL tear were enrolled a prospective study. imaging was performed at baseline (before surgeries) 6-month, 1-year 2-year reconstruction. included sagittal high-resolution, 3D fast spin-echo (CUBE) sequences for...
Although one study showed minimal progression of erosions in patients with rheumatoid arthritis (RA) year after TNFα inhibition therapy, no studies have investigated very early bone changes initiation anti-TNFα treatment. We the effects 3-month treatment on erosion and microarchitecture RA using high-resolution peripheral quantitative computed tomography (HR-pQCT). Patients (n = 27) (17 10 MTX-only group) underwent assessment disease activity score 28 joints (DAS-28), radiographs, 3-T...
Spread through air space (STAS) is a novel invasive pattern of lung adenocarcinoma and also risk factor for recurrence worse prognosis adenocarcinoma. This study aimed to develop validate computed tomography (CT)-based logistic regression model predict STAS in adenocarcinoma.This retrospective was approved by the institutional review board two centers included 578 patients (462 from center I 116 II) with pathologically confirmed identified 90 (19.5%) 28 II (24.1%) from. The maximum diameter,...
Because osteoporotic vertebral fracture (OVF) on chest radiographs is commonly missed in radiological reports, we aimed to develop a software program which offers automated detection of compressive (CVF) lateral radiographs, and emphasizes CVF specificity with low false positivity rate.
AIM:To investigate the role of curved planar reformations using multidetector spiral CT (MSCT) in diagnosis pancreatic and peripancreatic diseases. METHODS:From October 2001 to September 2003, 47 consecutive patients with or diseases, which were confirmed by operation, endoscopic retrograde cholangiopancreatography clinical follow-up, enrolled this study.CT scanning was performed at a MSCT four rows detector.A set images an effective thickness 1.0-2.0mm gap 0.5-1.0mm (50% overlap) acquired...
This pictorial review illustrates CT and MR imaging appearance of gastrointestinal stromal tumor (GIST) the stomach other lesions with similar appearance. GIST appears as well-defined enhanced masses characteristics subeppthial neoplasms. Majority are exophytic growth, but can also be intra-luminal growth. growth into a large mass without tract obstruction. Necrosis is often seen in results heterogeneous enhancement communication tract. MRI features several neoplasms mimicking GISTs...
To develop computed tomography (CT)-based models to increase the prediction accuracy of spread through air spaces (STAS) in clinical-stage T1N0 lung adenocarcinoma.
The aim of this study was to investigate whether adding delayed phase imaging can improve diagnostic ability (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET) in evaluating solitary pulmonary nodules (SPNs).28 patients with SPNs received dual-phase (18)F-FDG PET at 1h and 2h after injection during Feb 2009 Jun 2011were included retrospective study. Their final diagnosis confirmed by pathological examination 27 cases clinical follow-up 1 case. standardized uptake value...
Breast cancer is a highly harmful malignancy, which often causes great distress to patients and seriously affects their physical mental health. experience decreased appetite, eating, indigestion, in turn leads malnutrition, body wasting, resistance, immune compromise, progressive anemia, cachexia, and, as result, severe secondary infections. To investigate the efficacy evaluation of neoadjuvant chemotherapy breast by MRI, forty‐eight subjects treated at hospital from June 2014 August 2019...
Pancreatic adenocarcinoma is the most common malignancy of pancreas with high death rate. Preoperative imaging crucial for assessment disease and planning treatment. In this review, we discussed unusual findings pancreatic carcinoma. The CT MR include hypovascular mass, dilataion upstream biliary ducts, invasion to adjacent structures metastasis. uncommon include: a cystic mass without multiple masses or lesion diffusively infiltrating parts distorting its configuration.