A5014329425- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Cardiovascular Function and Risk Factors
- MRI in cancer diagnosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Invertebrate Immune Response Mechanisms
- Oral and Maxillofacial Pathology
- Infectious Diseases and Tuberculosis
- Tryptophan and brain disorders
- Cardiac Valve Diseases and Treatments
- Anorectal Disease Treatments and Outcomes
- Insect symbiosis and bacterial influences
- Radiomics and Machine Learning in Medical Imaging
- Ultrasound Imaging and Elastography
- Elasticity and Material Modeling
- Pelvic and Acetabular Injuries
- Pleural and Pulmonary Diseases
- Diverticular Disease and Complications
- Bone Tumor Diagnosis and Treatments
- Viral Infectious Diseases and Gene Expression in Insects
- Treatment of Major Depression
University of California, Los Angeles
2021-2023
UCLA Health
2021-2022
Ronald Reagan UCLA Medical Center
2021
Olive View-UCLA Medical Center
2021
Abstract Purpose of Review Triple-negative breast cancer (TNBC) represents about 15–20% all cancers and often presents as an aggressive with poor prognosis compared to other forms cancer. This article will review the clinical manifestations, imaging features, pathology correlation, treatment management, TNBC. Recent Findings While mammography ultrasound can be used diagnose TNBC, MRI is most accurate sensitive modality detect TNBC at nearly 100% sensitivity. Contrast-enhanced optimal study...
Perfusion-based collateral indices such as the perfusion index and hypoperfusion intensity ratio have shown promise in assessment of collaterals patients with acute ischemic stroke. We aimed to compare diagnostic performance compared angiographic outcome measures, including final infarct volume, growth, functional independence.
Undergraduate students participating in the UCLA Research Consortium for Functional Genomics (URCFG) have conducted a two-phased screen using RNA interference (RNAi) combination with fluorescent reporter proteins to identify genes important hematopoiesis Drosophila. This disrupted function of approximately 3500 and identified 137 candidate which loss leads observable changes hematopoietic development. Targeting RNAi maturing, progenitor, regulatory cell types key subsets that either limit or...
Collateral status has prognostic and treatment implications in acute ischemic stroke (AIS) patients. Unlike CTA, grading collaterals on MRA is not well studied. We aimed to evaluate the accuracy of assessing pretreatment AIS patients against DSA. with anterior circulation proximal arterial occlusion baseline subsequent endovascular were included. evaluated by two neuroradiologists independently using Tan Maas scoring systems. DSA American Society Interventional Therapeutic Neuroradiology...
Background Accurate estimation of ischemic core on baseline imaging has treatment implications in patients with acute stroke (AIS). Machine learning (ML) algorithms have shown promising results estimating using routine noncontrast computed tomography (NCCT). Objective We used an ML-trained algorithm to quantify volume NCCT a comparative analysis pretreatment magnetic resonance (MRI) diffusion-weighted (DWI) AIS. Methods Patients AIS who had both and MRI were enrolled. An automatic...
Early and accurate identification of tumor progression in patients with low-grade gliomas is challenging. We aimed to assess the role quantitative ADC analysis sequential follow-up as a potential imaging marker stability or progression.In this retrospective study, diagnosis glioma at least 12 months were retrospectively reviewed. Two neuroradiologists independently reviewed MR each patient determine using Response Assessment Neuro-Oncology criteria. Normalized mean (ADCmean) 10th percentile...
This study describes a method to acquire submillimeter resolution diffusion tensor MRI scans of the human heart in vivo. Imaging was performed healthy controls and patients with severe high flow-high gradient aortic stenosis. The images were processed generate helix angle maps cardiomyocyte orientation compared. range angles across myocardium higher subjects stenosis relative slope also increased
Motivation: Diffusion tensor imaging of the heart can be performed with sub-mm resolution. However, established metrics do not fully take advantage this improved Goal(s): We aimed to determine whether local gradients in helix angle (HA) could calculated and used characterize microstructural response load imposed by aortic stenosis. Approach: Voxel-wise maps radial, circumferential, minimum maximum HA were generated. Results: The radial gradient was reduced stenosis, but coherence well...
Motivation: DTI data in the heart are currently averaged to yield per-patient values that cannot detect local variations microstructural microenvironment. Goal(s): We aimed develop a voxel-based phenomapping approach cluster voxels myocardium into distinct groups based on their properties. then used compare subjects with aortic stenosis (AS) age-matched controls (CTL). Approach: A population matrix of was created using z-score normalization and evaluated k-means clustering (k=4). Results: 4...
While isolated spontaneous pneumomediastinum (SPM) is not commonly associated with viral respiratory infections, several cases of SPM in the context coronavirus disease 2019 (COVID-19) have emerged.Isolated remains seldom presented current literature.We will present clinical presentation and hospital course four patients hospitalized COVID-19 who were on mechanical ventilation.We also review all from literature compare these for similarities possible patterns that may help elucidate risk...
An aneurysmal bone cyst (ABC) is a rare benign expansile lesion of the that consists hemorrhagic cystic spaces separated by fibrous connective tissue containing osteoid and multinucleated giant cells. The may be primary or secondary. We present case ABC in 7-month-old girl who had growing, antibiotic-refractory mass left chest wall. A computed tomography confirmed anatomic location mass, but percutaneous image-guided biopsy and video-assisted thoracoscopic surgery performed during...
Background and Purpose: Accurate estimation of ischemic core on baseline imaging has treatment implications in patients with acute stroke (AIS). Machine learning (ML) algorithms have shown promising results estimating using routine non-contrast CT (NCCT). We used a ML-trained algorithm to quantify volume NCCT compared the concurrent diffusion MRI as reference standard AIS. Methods: analyzed consecutive anterior circulation AIS who had (pretreatment) (DWI). Ischemic lesion was calculated...
Ketamine in subanesthetic doses became popular as a recreational drug for its strong, quickly achievable antidepressant effect and short-acting, well-tolerated psychotomimetic (hallucinogenic dissociative) effect. Numerous cases of genitourinary system dysfunction associated with ketamine use have been reported. We describe case ketamine-use-related symptoms 23-year-old man who was found to acute cystitis history using ketamine. also discuss the epidemiology, clinical presentation, some...