- Frailty in Older Adults
- Nutrition and Health in Aging
- Cancer survivorship and care
- Health Systems, Economic Evaluations, Quality of Life
- Phonetics and Phonology Research
- Palliative Care and End-of-Life Issues
- Dental Health and Care Utilization
- Oral microbiology and periodontitis research
- HIV/AIDS oral health manifestations
- Linguistic Variation and Morphology
- Anesthesia and Pain Management
- Topological and Geometric Data Analysis
- Body Composition Measurement Techniques
- Lexicography and Language Studies
- Geriatric Care and Nursing Homes
- Dialysis and Renal Disease Management
- Homotopy and Cohomology in Algebraic Topology
- Cancer-related cognitive impairment studies
- Intensive Care Unit Cognitive Disorders
- Childhood Cancer Survivors' Quality of Life
- Dementia and Cognitive Impairment Research
- Cardiac, Anesthesia and Surgical Outcomes
- Chronic Disease Management Strategies
- Management of metastatic bone disease
- Aging and Gerontology Research
National University Hospital
2017-2025
National University Health System
2017-2024
National University of Singapore
2017-2024
Keck Hospital of USC
2023
Bronson Methodist Hospital
2020
Albion College
2020
Michigan State University
2020
University of California, Berkeley
1970-2019
The University of Melbourne
2019
University of Virginia
2019
OBJECTIVES To determine the prevalence of fear falling (FOF) and fear‐related activity restriction (FAR) their association with frailty, sarcopenia, gait speed grip strength, cognitive impairment, depression, social isolation, self‐perceived health, vision. DESIGN Observational cross‐sectional study. SETTING Community. PARTICIPANTS A total 493 community‐dwelling older adults, 60 years older. MEASURES FOF FAR were assessed using validated single closed‐ended questions. Questionnaire was...
Background Body mass index (BMI) is an inadequate marker of obesity, and cannot distinguish between fat mass, free distribution adipose tissue. The purpose this study was twofold. First, to assess cross-sectional relationship BMI with (FMI), (FFMI) ratio (FM/FFM). Second, the association FMI, FFMI FM/FFM physical function including sarcopenia, cognition in pre-frail older adults. Methods Cross-sectional 191 participants ≥ 65 years, 57.1% females. Data collected on demographics, [Montreal...
Quality of life is a major criterion when decisions regarding resuscitation, reconstruction, and rehabilitation patients with massive burn injuries are being considered. There has been little research focusing on quality following involving more than 50 percent total body surface area in the adult population. The authors' goals were to describe identify specific clinical functional indices that predict good injuries.Using prospective study design, 47 who survived between 1980 2001 recruited...
With aging population and consequent increase in associated prevalence of frailty, dementia multimorbidity, primary care physicians will be overwhelmed with the complexity psychosocial clinical presentation. Geriatric syndromes including sarcopenia, cognitive impairment anorexia either isolation or combination is increased risk adverse outcomes if recognised early, appropriately managed, lead to decreased disability. Primary practices are often located residential setting, ideal position...
The prevalence of anemia and its impact on frailty physical function amongst the multiethnic older populations in Southeast Asian (SEA) countries are often not well studied. Singapore, a nation comprised communities, is one most rapidly aging population globally. We aim to evaluate frailty, Healthy Older People Everyday (HOPE)- an epidemiologic population-based study community-dwelling adults Singapore.
Intervertebral disc degeneration associated back pain is the most common cause of disability worldwide; however, no safe and effective treatments have been available. Here, we report a new functionalized nanofullerene conjugated with peptide that binds specifically to formyl receptor-1 (FPR-1) expressed on activated macrophages. The nanoparticle (aka FT-C60) was synthesized by conjugating carboxyl-C60 primary amine group fluorescence dye for easy detection. characterized X-ray photoelectron...
Delirium is highly prevalent in hospitalised older adults, under-diagnosed and associated with poor outcomes. We aim to determine (i) association of frailty measured using Hospital Frailty Risk Score (HFRS) delirium, (ii) impact delirium on mortality, 30-days readmission, extended length stay (eLOS) cost (eCOST).Retrospective cohort study was conducted 902 adults ≥75 years discharged from an academic tertiary hospital between March September 2021. Data obtained administrative...
Multicomponent exercise program have shown to improve function and cognition in older adults but studies on pre-frail the primary care setting are limited. This study aimed i) evaluate impact of 6 months (Ex) versus complementary effect 3 cognitive stimulation therapy (CST) Ex (Ex+CST) physical function, muscle mass control group at 3, 12 ii) inflammatory biomarkers such as Interleukin-6 (IL-6) Tumor Necrosis Factor Alpha (TNF-α).
Metabolic syndrome (MetS) and frailty are both associated with increased morbidity mortality. Frailty is reduced quality of life (QoL) but association QoL MetS have produced mixed results suggesting that other factors such as disease burden, obesity depression may a more significant influence. We aim to investigate the demographics frail participants MetS, relationship between in MetS. Cross-sectional population study involving 292 older adults ≥ 65 years was defined using Modified ATP III...
One of the perennial problems in diachronic linguistics is how to reconcile, on one hand, Neogrammarian postulate sound laws operating without exception, and, other embarrassingly numerous irregularities we observe many languages. On most occasions linguists have attempted solve problem by positing interdialectal borrowing or analogical levelling and largely overlooked possibility gradual diffusion phonological changes across lexicon. As a result lexical gradualness changes, exceptions may...
While the notion of naturalness or plausibility has been a tacit guiding principle for past generations phonologists, effort to accord theoretical status and incorporate this into descriptive formalism linguistic theory was major innovation by generative school. In accordance with what we may refer as ‘formalness condition’, generativist requires that substantive phonological process be explicitly recognizable in very used state process. The lively interest on-going search ‘natural’...
While hospitalist and internist inpatient care models dominate the landscape in many countries, geriatricians internists are at frontlines managing hospitalized older adults countries such as Singapore United Kingdom. The primary aim of this study was to determine outcomes for patients cared by compared with non-geriatrician-led teams.A retrospective cohort 1,486 Internal Medicine aged ≥75 years admitted between April September 2021 conducted. They were either under geriatrician or...
The modern prevalence of primary tumours causing metastatic bone disease is ill-defined in the oncological literature. Therefore, purpose this study to identify setting disease, as well reported rates pathological fracture, postoperative complications, 90-day mortality, and 360-day mortality for each tumour subtype.The Premier Healthcare Database was queried all patients who were diagnosed with from January 2015 December 2020. subtypes tabulated. Rates long following surgical treatment...
Structured Abstract Objectives To conduct a prospective pilot trial to test the clinical efficacy and accuracy of newly developed Bluetooth‐enabled retainer, which was synchronized with an iOS mobile application, cloud database provider webpage. Setting Sample Population Five orthodontic residents in university setting. Material Methods At delivery retainers (T0), each participant given logbook iPod Touch installed application. Participants were instructed wear retainer for 12 hours per day...