- Paraquat toxicity studies and treatments
- Brain Metastases and Treatment
- Traditional Chinese Medicine Analysis
- Gastric Cancer Management and Outcomes
- Acute Kidney Injury Research
- Infectious Diseases and Tuberculosis
- CNS Lymphoma Diagnosis and Treatment
- MicroRNA in disease regulation
- Glioma Diagnosis and Treatment
- Circular RNAs in diseases
- Diagnosis and treatment of tuberculosis
- Management of metastatic bone disease
- Andrographolide Research and Applications
- Cancer-related molecular mechanisms research
- Traumatic Brain Injury and Neurovascular Disturbances
- Cancer Diagnosis and Treatment
- Congenital Diaphragmatic Hernia Studies
- Meningioma and schwannoma management
- Tuberculosis Research and Epidemiology
- Pediatric health and respiratory diseases
- Methemoglobinemia and Tumor Lysis Syndrome
- Ginger and Zingiberaceae research
Second Hospital of Hebei Medical University
2012-2021
Hebei Medical University
2004-2021
Daping Hospital
2021
Shandong First Medical University
2021
Long non-coding RNA (lncRNA) is identified as an important regulator involved in oral squamous cell carcinoma (OSCC) tumorigenesis. This study aimed to investigate the functional role and underlying mechanism of LINC00662 OSCC.The expression levels LINC00662, miR-144-3p, enhancer zeste homolog 2 (EZH2) mRNA were quantified with quantitative real-time polymerase chain reaction OSCC tissues lines. Western blot analysis was used assay E-cadherin, Vimentin, EZH2. Cell proliferation, migration,...
Objective: To evaluate the clinical efficacy of meningeal carcinomatosis (MC) treated by intrathecal chemotherapy (IC) and analyzes prognostic factors.Methods: The follow-up data 33 MC patients was collected retrospectively analyzed. Potential factors such as age, gender, primary cancer, transfer time, presence brain metastasis, intracranial pressure, protein, glucose, vascular endothelial growth factor (VEGF), eastern cooperative oncology group (ECOG) performance status (PS), systemic...
Objective To investigate the effects of parenteral nutrition (PN) including ω-3 fish-oil emulsion on nutritional state, inflammatory response, and prognosis in patients with acute paraquat poisoning. Methods Patients randomized to receive medium chain triglycerides (MCT)/long (LCT)-based PN (control group) or MCT/LCT-based containing (intervention were compared for 90-day survival short-term treatment efficacy. Results Tumour necrosis factor-α levels significantly lower intervention group (...
Objective To further study the prognosis of paraquat(PQ ) induced lung injury by means follow-up pulmonary function at 6 months poisoning in long-term survival patients with acute PQ poisoning. Methods The data 50 admitted from September 2010 to July 2012, and were retrospectively reviewed, divided into mild group severe according manifestations CT. The measurement VC%(vital capacity), FVC%(forced vital FEV1.0%(forced expiratory volume), FEV1.0/FVC%, MMEF%(maximal mid-expiratory flow)...
Objective To analyze the occurrence of postoperative complications video-assisted thoracoscopic mini incision in treatment lung cancer. Methods 158 patients with cancer who were treated our hospital randomly divided into control group and observation group. The was routine thoracotomy, while small incision. number severity analyzed. Results The incidence lower than that (50.63% vs.69.62%, P<0.05), there statistically significant difference location between two groups...
Objective To investigate the relationship between rs17525495 locus polymorphism of leukotriene A4 hydrolase (LTA4H) gene and severity tuberculous meningitis (TBM). Methods A total 184 TBM patients from Department Neurology, Second Hospital Hebei Medical University January 2014 to October 2016 were selected as research subjects. According British Research Council criteria, was divided into three stages. The single nucleotide LTA4H sequenced, general case data, clinical manifestations...
Objective To observe the nutritional biochemical indicators of paraquat poisoning patients, analyze and compare status patients understand changing trend each indicator. Methods A total 104 with acute who were admitted to emergency department Second Hospital Hebei Medical University from December 2015 2017 enrolled, divided into cure group (patients survived >30 days) death group. Nutritional including serum protein (ALB, PA, TP) lipids (TCh, TG, LDL) selected for dynamic observation....