A5103060876- Paraquat toxicity studies and treatments
- Fatigue and fracture mechanics
- Structural Load-Bearing Analysis
- Mechanical Behavior of Composites
- Traditional Chinese Medicine Analysis
- GDF15 and Related Biomarkers
- Spinal Cord Injury Research
- Quantum Information and Cryptography
- Biochemical Acid Research Studies
- Paraoxonase enzyme and polymorphisms
- Ultrasonics and Acoustic Wave Propagation
- Osteoarthritis Treatment and Mechanisms
- Cerebral Palsy and Movement Disorders
- Mechanical stress and fatigue analysis
- Lower Extremity Biomechanics and Pathologies
- Vitamin K Research Studies
- Peroxisome Proliferator-Activated Receptors
- Quantum Computing Algorithms and Architecture
- Andrographolide Research and Applications
- Transplantation: Methods and Outcomes
- Ginger and Zingiberaceae research
- Atherosclerosis and Cardiovascular Diseases
- Total Knee Arthroplasty Outcomes
- Fire effects on concrete materials
- Acute Ischemic Stroke Management
Hebei Medical University
2012-2024
Second Hospital of Hebei Medical University
2012-2024
Second Affiliated Hospital of Xi'an Jiaotong University
2024
Xi'an University of Technology
2024
Chongqing University
2013-2023
Jilin University
2022
State Key Laboratory of Automotive Simulation and Control
2022
Wenzhou Medical University
2017
Zhejiang Taizhou Hospital
2017
Texas College
1993
Accurate prediction of fatigue failure behavior and life structures or materials under multi-axial loading are important for engineering application. In this work, a high-cycle model based on the critical plane criterion is proposed with considering influences material property path initiation growth cracks. A parameter, defined as ratio tensile yield strength σy torsional τy, introduced to describe mechanical properties material. For σy/τy< 3, it considered that crack load mainly controlled...
Objective To investigate the effects of parenteral nutrition (PN) including ω-3 fish-oil emulsion on nutritional state, inflammatory response, and prognosis in patients with acute paraquat poisoning. Methods Patients randomized to receive medium chain triglycerides (MCT)/long (LCT)-based PN (control group) or MCT/LCT-based containing (intervention were compared for 90-day survival short-term treatment efficacy. Results Tumour necrosis factor-α levels significantly lower intervention group (...
Early identification of patients requiring ventilator support will be beneficial for the outcomes botulism. The present study aimed to establish a new scoring system predict mechanical ventilation (MV) botulism patients.
Spinal cord injury (SCI) is a debilitating condition that often results in paralysis and lifelong medical challenges. Research has shown epigenetic modifications, particularly histone acetylation, play role neuroprotection following hypoxic-ischemic events SCI. The objective of this study was to explore the effects H3K27 along with its underlying mechanisms, on tolerance hypoxia ischemia
Coupled effects of hygrothermal environment and geometrical parameters on the failure a double-lap, single-bolt composite joint are investigated numerically. The studied include ratio end distance to hole diameter (e/D) that width (w/D). Three representative environmental conditions, including −55 °C/dry (CTD), 23 (RTD) 70 °C/wet (ETW), considered. Numerical progressive damage models (PDMs) consider established predict load mode joints. Good agreement between predicted experimental results...
To explore the correlation between selection of time window for acute cerebral infarction (ACI) and efficacy intravascular stent implantation.The clinical data 84 ACI patients treated in our hospital from March 2019 to 2020 were selected retrospective analysis, all study subjects received implantation, after discharge, assessed by Modified Rankin Scale (mRS) divided into good prognosis group (n = 46, mRS score ≤2 points) poor 38, >2 points). The two groups at admission underwent univariate...
Pulmonary fibrosis is one of the most important pathological processes associated with paraquat (PQ) poisoning. 5‑Aminosalicylic acid (5‑ASA) has been shown to be a promising agent against fibrotic diseases. In present study, alleviating role 5‑ASA was evaluated in rat model pulmonary induced by PQ intragastric poisoning (80 mg/kg). Wistar rats were divided into control, PQ, (30 mg/kg daily, 14 days) and + groups. Histological examination revealed congestion, edema inflammatory cell...
To study the mechanism of paraquat (PQ) -induced renal injury in rats, expression changes ICAM-1 to assess protective effect Melatonin PQ poisoning.Ninety adult healthy Sprague-Dawley (SD) rats were divided into three groups at random.30 rats; Poisoned group: 30 rats. Control group and treated intragastrically with 1 ml (50 mg/kg) diluted normal saline. groupwere same dose saline as group. given a 10 mg/kg (once daily, intraperitoneally) Pathology tissue oberserved by HE staining, electron...
Objective To further study the prognosis of paraquat(PQ ) induced lung injury by means follow-up pulmonary function at 6 months poisoning in long-term survival patients with acute PQ poisoning. Methods The data 50 admitted from September 2010 to July 2012, and were retrospectively reviewed, divided into mild group severe according manifestations CT. The measurement VC%(vital capacity), FVC%(forced vital FEV1.0%(forced expiratory volume), FEV1.0/FVC%, MMEF%(maximal mid-expiratory flow)...
Paraoxonase (PON) is a hydrolyase correlated with many chronic diseases. The use of 9-(4-chlorophenyloxycarbonyl)-10-methylacridinium triflate ester (CPOCMA) as substrate for determination serum arylesterase PON activity had been reported. It meaningful to compare this phenyl acetate further samples patients coronary heart disease (CHD, n=104). Correlations CHD and also age were analyzed. There was no significant difference in (based on the CPOCMA or acetate) between inpatients controls at...
Coupled effects of hygrothermal environment and geometrical parameters on the failure a double-lap, single-bolt composite joint were investigated numerically. The studied include ratio end distance to hole diameter (e/D) that width (w/D). Three representative environmental conditions, including −55 °C/dry (CTD), 23 (RTD) 70 °C/wet (ETW), considered. Numerical progressive damage models (PDMs) consider established predict load mode joints. Good agreement between predicted experimental results...
Objective To determine CD4+ CD28null T cells and their relationship with the microinflammatory state left ventricular hypertrophy in end-stage renal disease (ESRD) patients. Methods One hundred twenty ESRD patients were selected, including sixty non-dialytic stage 5 chronic kidney patients(CKD5 stage) thirty maintenance dialysis patients(CKD5D stage). In addition, healthy adults from hospital medical center selected as control group.Flow cytometry was used to detect frequencies of...
Objective To observe the nutritional biochemical indicators of paraquat poisoning patients, analyze and compare status patients understand changing trend each indicator. Methods A total 104 with acute who were admitted to emergency department Second Hospital Hebei Medical University from December 2015 2017 enrolled, divided into cure group (patients survived >30 days) death group. Nutritional including serum protein (ALB, PA, TP) lipids (TCh, TG, LDL) selected for dynamic observation....
Abstract Pulmonary fibrosis is one of the most common complications paraquat (PQ) poisoning, which becomes focus treatment. More and more studies have found that 5-Aminosalicylic acid (5-ASA) may be a prospective therapy against fibrotic diseases. In present study, we observed whether 5-ASA could attenuate pulmonary in PQ-treated rats human lung fibroblasts (WI38VA13) cells, subsequently explored possible underlying mechanisms. Wistar were divided into control group, PQ group + group. Rats...