A5101947159- Aquaculture Nutrition and Growth
- Aquaculture disease management and microbiota
- Animal Nutrition and Physiology
- Adipose Tissue and Metabolism
- Peroxisome Proliferator-Activated Receptors
- Reproductive biology and impacts on aquatic species
- Liver Disease Diagnosis and Treatment
- Fatty Acid Research and Health
- Enzyme Catalysis and Immobilization
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Electrochemical sensors and biosensors
- Ginger and Zingiberaceae research
- MRI in cancer diagnosis
- Birth, Development, and Health
- Endometrial and Cervical Cancer Treatments
- Autophagy in Disease and Therapy
- Environmental Toxicology and Ecotoxicology
- Infant Nutrition and Health
- Physiological and biochemical adaptations
- Genomics, phytochemicals, and oxidative stress
- Regulation of Appetite and Obesity
- Cholesterol and Lipid Metabolism
- Cancer, Hypoxia, and Metabolism
- Berberine and alkaloids research
Shanghai Jiao Tong University
2016-2025
Weifang Chinese Medicine Hospital
2024
University of Saint Joseph
2024
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2024
Wenzhou Medical University
2024
Westlake University
2023
Air Force Medical University
2023
ETH Zurich
2022
Binzhou University
2022
Binzhou Medical University
2022
Significant embryo loss remains a serious problem in pig production. Reactive oxygen species (ROS) play critical role embryonic implantation and placentation. However, the potential mechanism of ROS on porcine trophectoderm (pTr) cell fate during peri-implantation period has not been investigated. This study aimed to elucidate effects pTr phenotypes regulatory attachment differentiation. Herein, results showed that exogenous H 2 O inhibited viability, arrested cycle at S G2/M phases,...
High-fat diets may promote growth, partly through their protein-sparing effects. However, high-fat often lead to excessive fat deposition, which have a negative impact on fish such as poor growth and suppressive immune. Therefore, this study investigated the effects of fat-rich diet mechanisms deposition in liver. Three-hundred blunt snout bream (Megalobrama amblycephala) juveniles (initial mass 18.00±0.05 g) were fed with one two (5% or 15% fat) for 8 weeks. β-Oxidation capacity regulation...
This study investigated the effects of weaning on hepatic redox status, apoptosis, function, and mitogen-activated protein kinase (MAPK) signaling pathways during first week after in piglets. A total 12 litters piglets were weaned at d 21 divided into group (WG) control (CG). Six from each slaughtered 0 (d 20, referred to weaning), 1, 4, 7 weaning. Results showed that significantly increased concentrations free radicals H2O2 NO, malondialdehyde (MDA), 8-hydroxy-2'-deoxyguanosine (8-OHdG),...
A feeding trial was conducted to investigate the effects of dietary fructooligosaccharide (FOS) on growth performance, body composition, intestinal enzymes activities and histology fingerling Megalobrama amblycephala. total 1200 fish (1.42 ± 0.01 g) were fed diets containing graded levels FOS (0, 0.5, 1, 2, 4 8 g kg−1 diet) for weeks in a recirculating system indoor. The weight gain, specific rate (SGR) survival all improved supplementation fish. Increasing resulted both higher whole-body...
High-fat diets may have favorable effects on growth, partly based protein sparing, but high-fat often lead to fatty liver (excessive fat deposition in the liver), which be deleterious fish growth and health. The goal of this study was therefore investigate possible adverse how they develop. Juvenile Blunt Snout Bream Megalobrama amblycephala (initial weight ± SE = 17.70 0.10 g) were fed two (5% [control] or 15% fat). After 8 weeks, that diet showed a high rate mortality poor growth....
Abstract The sid-1 (systemic interference defective) gene encodes a transmembrane protein that is an important participator in the systemic RNAi pathway and has been reported several organisms. In insects, sid-1-like genes were described from Tribolium castaneum, Apis mellifera, Bombyx mori Schistocerca americana, but not found Drosophila melanogaster Anopheles gambiae. To investigate whether this occurs aphid species, RT-PCRs performed using degenerate primers designed conserved motif of...
Blunt snout bream (Megalobrama amblycephala) are susceptible to hepatic steatosis when maintained in modern intensive culture systems. The aim of this study was investigate the potential roles microRNAs (miRNAs) diet-induced species. MiRNAs, small non-coding RNAs that regulate gene expression at posttranscriptional level, involved diverse biological processes, including lipid metabolism. Deep sequencing RNA libraries from blunt fed normal-fat and high-fat diets identified 202 (193 known 9...
This study was conducted to investigate the effects of fructooligosaccharide (FOS) and Bacillus licheniformis (B. licheniformis) on growth performance, body composition, intestinal enzymes activities gut histology Megalobrama terminalis. Nine experimental diets were formulated contain three FOS levels (0, 3 6 g kg−1) B. 1 5 × 107 CFU g−1) following a factorial design. Accordingly, named as 0/0, 0/3, 0/6, 1/0, 1/3, 1/6, 5/0, 5/3 5/6 licheniformis/FOS). At end 8-week feeding trial, weight gain...
Abstract Gas-phase enzymatic catalysis has been long pursued but not yet utilized in industrial processes due to many limitations. Herein, we report a hydroxyl-rich graphene oxide (GO) aerogel that can preserve the activity and stability an anhydrous gas flow by providing water-like microenvironment. Lipase immobilized GO exhibits 5 10-fold increase apparent than lyophilized lipase powder transesterification of geraniol vinyl acetate phase maintains initial for more 500 h. The solid-state...
Nicotinamide mononucleotide (NMN), a key intermediate of nicotinamide adenine dinucleotide, plays an important in anti-aging and disease. Lactococcus lactis, probiotic lactic acid bacteria (LAB), has shown great potential for the biosynthesis NMN, which will significantly affect effects dairy products.We used CRISPR/nCas9 technique to knockout nadR gene L. lactis NZ9000 enhance accumulation NMN by 61%. The nadE* from Francisella tularensis with codon optimization was heterologous NZ9000ΔnadR...
Abstract Maternal age at childbearing has continued to increase in recent decades. However, whether and how it influences offspring adult traits are largely unknown. Here, using body size as the primary readout, we reveal that maternal rather than paternal an evolutionarily conserved effect on humans, Drosophila , Caenorhabditis elegans . Elucidating mechanisms of such effects humans other long-lived animals remains challenging due their long life course difficulties conducting vivo studies....