A5100680089- Aquaculture Nutrition and Growth
- Plant nutrient uptake and metabolism
- Aquaculture disease management and microbiota
- Plant Micronutrient Interactions and Effects
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Skin and Cellular Biology Research
- MicroRNA in disease regulation
- Antibiotic Resistance in Bacteria
- Genetic diversity and population structure
- Cancer-related gene regulation
- Fish Biology and Ecology Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- interferon and immune responses
- Blood properties and coagulation
- Gut microbiota and health
- Bacterial biofilms and quorum sensing
- Soil Carbon and Nitrogen Dynamics
- Molecular Biology Techniques and Applications
- Crop Yield and Soil Fertility
- Turtle Biology and Conservation
- Physiological and biochemical adaptations
- Esophageal Cancer Research and Treatment
- Bacterial Identification and Susceptibility Testing
- Genetic and phenotypic traits in livestock
Changhai Hospital
2018-2025
Second Military Medical University
2018-2025
Shanghai Academy of Agricultural Sciences
2019-2025
Hunan Agricultural University
2014-2025
Anhui Medical University
2022-2025
First Affiliated Hospital of Anhui Medical University
2025
National Institute for Communicable Disease Control and Prevention
2024
Third Affiliated Hospital of Sun Yat-sen University
2024
Sun Yat-sen University
2024
Fudan University
2023
Abstract Pathogenesis of colorectal cancer (CRC) is associated with alterations in gut microbiome. Previous studies have focused on the changes taxonomic abundances by metagenomics. Variations function intestinal bacteria CRC patients compared to healthy crowds remain largely unknown. Here we collected fecal samples from and volunteers characterized their microbiome using quantitative metaproteomic method. We identified quantified 91,902 peptides, 30,062 microbial protein groups, 195 genera...
Low phosphorus availability is a major abiotic factor constraining wheat growth. The molecular mechanisms of the whole genome under low-phosphorus stress are still unclear. To obtain information on gene expression in seedlings stress, transcriptome sequencing was performed roots and leaves. results showed that 2,318 (1,646 upregulated 672 downregulated) transcripts were differentially expressed leaves, 2,018 (1,310 708 roots. Further analysis these genes (DEGs) mainly enriched carbon...
Cadmium (Cd) is highly toxic to living organisms. This study aimed elucidate the regulation of gene expression in rice shoots under Cd stress. Rice plants were exposed 0, 50, 75, 100 μmol/L CdCl2 hydroponic culture for 7 d. Transcriptional changes examined by transcriptome sequencing techniques. A total 2197 DEGs (987 up-regulated and 1210 down-regulated) detected exposure 75 CdCl2. GO KEGG enrichment analyses showed that genes encoding auxin-responsive protein IAA peroxidase up-regulated,...
Nitrogen (N) is one of the essential macronutrients that plays an important role in plant growth and development. Unfortunately, low utilization rate nitrogen has become main abiotic factors affecting crop growth. Nevertheless, little research been done on molecular mechanism wheat seedlings resisting or adapting to environment. In this paper, response against stress at phenotypic changes gene expression level were studied. The results showed height, leaf area, shoot root dry weight, total...
Abstract Background The channel catfish (Ictalurus punctatus), a species native to North America, is one of the most important commercial freshwater fish in world, especially United States' aquaculture industry. Since its introduction into China 1984, both cultivation area and yield this have been dramatically increased such that now leading producer catfish. To aid genomic research species, data sets as genetic linkage groups, long-insert libraries, physical maps, bacterial artificial...
Abstract The discovery of electrides, in particular, inorganic electrides where electrons substitute anions, has inspired striking interests the systems that exhibit unusual electronic and catalytic properties. So far, however, experimental studies such are largely restricted to ambient conditions, unable understand their interactions between electron localizations geometrical modifications under external stimuli, e.g., pressure. Here, pressure‐induced structural evolutions Ca 2 N by situ...
A high-density genetic linkage map is of particular importance in the fine mapping for important economic traits and whole genome assembly aquaculture species. The channel catfish (Ictalurus punctatus), a species native to North America, one most commercial freshwater fish world. Outside United States, China has become major producer consumer after experiencing rapid development past three decades. In this study, based on restriction site associated DNA sequencing (RAD-seq), was constructed...
Abstract Background The spread and outbreak of Enterobacteriaceae producing OXA-48-like carbapenemases have become more prevalent in China. Results A total 62 non-duplicated OXA-232-producing K. pneumoniae (OXA232Kp) were isolated between 2015 2017. An OXA232Kp was observed burn ICU. isolates all belongs to ST15 categorized into two PFGE types (A B). Type dominated the isolates, which contained 61 clinical divided 10 subtypes (A1-A10). In addition, most strains exhibited low-level...
ABSTRACT Background Monocyte‐derived macrophages and microglia initially adopt an anti‐inflammatory phenotype following stroke but later transition to a pro‐inflammatory state. The mechanisms underlying this phenotypic shift remain unclear. This study investigates the activation dynamics of molecular signaling pathways in after stroke. Methods We utilized publicly available single‐cell RNA sequencing datasets examine alongside microglia. Male C57BL/6 mice underwent transient middle cerebral...
Bacterial antimicrobial resistance (AMR) is among the most significant challenges to current human society. Exposing bacteria antibiotics can activate their self-saving responses, e.g., filamentation, leading development of bacterial AMR. Understanding molecular changes during responses reveal new inhibition methods drug-resistant bacteria. Herein, we used an online microfluidics mass spectrometry system for real-time characterization metabolic filamentation under stimulus antibiotics....
Selenium (Se) is an essential micronutrient for the human body and closely linked to health. Rice (Oryza sativa L.), as a major staple food globally, primary source of Se intake humans. To better achieve biofortification in rice, it crucial understand molecular mechanisms behind rice's response different concentrations. This study investigates morphological transcriptomic responses rice seedlings low (1 µM, LSe) high (10 HSe) concentrations compared control (CK). Morphological analyses...
Background/Objectives: The Chinese soft-shelled turtle (Pelodiscus sinensis) is an important species in freshwater aquaculture. Genetic admixture and degradation due to rapid industry expansion threaten sustainable development. This study aims assess the genetic diversity structure of six P. sinensis populations for better management. Methods: We combined morphological analysis microsatellite markers evaluate populations. A discriminant function based on morphology was developed, achieving...
Introduction. Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) is an emerging pathogen associated with severe clinical outcomes, prompting urgent investigation into its genomic characteristics and pathogenic potential.Hypothesis/Gap Statement. We hypothesize that CR-hvKP strains exhibit high-level resistance high virulence, leading to their rapid spread in settings posing a serious threat treatment.Aim. The aim of the study was investigate phenotype genotype strains, reveal...
ABSTRACT Circulating cell‐free DNA (cfDNA) is a large molecule that plays central role in the pathogenesis of SLE. It target antigen autoantibodies and main component immune complexes. Due to differences content cfDNA detected different studies, cannot be used as strong diagnostic basis for SLE at present. As an active cfDNA, correlation between double‐stranded (dsDNA) has not been fully studied. The detection dsDNA may provide more accurate diagnosis treatment SLE, in‐depth study patients...
We investigated the locations of 5S and 45S rDNA in Gossypium diploid A, B, D, E, F, G genomes tetraploid genome (AD) using multi-probe fluorescent situ hybridization (FISH) for evolution analysis genus. The numbers sizes, synteny relationships between were revealed as double-probe all species, rDNA-bearing chromosomes identified D AD with one more probe that is single-chromosome-specific BAC clone from G. hirsutum (A1D1). Two to four loci found diploid-species except two incanum (E4), same...
Autolysis of Coprinopsis cinerea fruiting bodies affects its commercial value. In this study, a mutant C. that exhibits pileus expansion without autolysis was obtained using ultraviolet mutagenesis. This suggests and involve different enzymes or proteins. Among the detected hydrolytic enzymes, only β-1,3-glucanase activity increased with pilei in wild-type strain, but increase abolished mutant. β-1,3-glucanases plays major role autolysis. Although there are 43 possible β-1,3-glucoside...