Jian‐Jun Li

ORCID: 0000-0003-1251-6074
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About
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Research Areas
  • Lipoproteins and Cardiovascular Health
  • Coronary Interventions and Diagnostics
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Atherosclerosis and Cardiovascular Diseases
  • Cancer, Lipids, and Metabolism
  • Cardiac Imaging and Diagnostics
  • Acute Myocardial Infarction Research
  • Lipid metabolism and disorders
  • Adipokines, Inflammation, and Metabolic Diseases
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Blood groups and transfusion
  • Kawasaki Disease and Coronary Complications
  • Coronary Artery Anomalies
  • Liver Disease Diagnosis and Treatment
  • Blood Coagulation and Thrombosis Mechanisms
  • Hepatitis C virus research
  • Computational Drug Discovery Methods
  • Cardiovascular Function and Risk Factors
  • Pharmaceutical Economics and Policy
  • Pancreatitis Pathology and Treatment
  • Diabetes and associated disorders
  • Immune Cell Function and Interaction
  • Systemic Lupus Erythematosus Research
  • Protease and Inhibitor Mechanisms
  • Atrial Fibrillation Management and Outcomes

Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025

Zhujiang Hospital
2025

Southern Medical University
2025

Fu Wai Hospital
2015-2024

Zoucheng People's Hospital
2024

Sun Yat-sen University
2020-2024

Sun Yat-sen University Cancer Center
2024

Beijing Tongren Hospital
2012-2024

First Affiliated Hospital of Anhui Medical University
2023-2024

Anhui Medical University
2019-2024

Triglyceride glucose (TyG) index is a novel marker for metabolic disorders and recently it has been reported to be associated with cardiovascular disease (CVD) risk in apparently healthy individuals. However, the prognostic value of TyG patients stable coronary artery (CAD) not determined.We conducted nested case-control study among 3,745 CAD. Patients were followed up 11,235 person-years. The events (CVEs) defined as all-cause death, non-fatal myocardial infarction (MI), stroke...

10.21037/jtd.2018.10.79 article EN cc-by-nc-nd Journal of Thoracic Disease 2018-11-01

Background: All versions of the Montreal Cognitive Assessment (MoCA) lack population-based data 80-plus individuals. The norms and cut-off scores for mild cognitive impairment (MCI) dementia MoCA are different among five Chinese version

10.3233/jad-141278 article EN Journal of Alzheimer s Disease 2014-12-23

Multiple myeloma (MM) is the second most common hematologic neoplasms and an appropriate in vivo environment for cells has potential implications initiation, progression, metastasis of MM. Exosomes, entities carrying microRNAs (miRNAs) to target locations, participate cross-talk between nonmalignant components environment. This study disclosed emerging roles circulating exosome-associated miRNAs drug resistance (DR) To this end, medical records consecutively hospitalized MM patients, who...

10.18632/oncotarget.9021 article EN Oncotarget 2016-04-26

Diabetic cardiomyopathy (DCM), one of the common complications diabetes, presents as a specific with anomalies in structure and function heart. With increasing prevalence DCM has high morbidity mortality worldwide. Recent studies have found that pyroptosis, programmed cell death accompanied by an inflammatory response, exacerbates growth genesis DCM. These provide theoretical basis for exploring potential treatment Therefore, this review aims to summarise possible mechanisms which pyroptosis...

10.3389/fendo.2023.1322907 article EN cc-by Frontiers in Endocrinology 2024-01-05

Renal diseases in diabetes include diabetic nephropathies (DN) and non-diabetic renal (NDRD). The clinical differentiation between these two categories is usually not so clear effective. This study aims to develop a quantified differential diagnostic model.We consecutively screened the patients with overt proteinuria but no severe failure for kidney biopsy from 1993 2003. finally enrolled 110 were divided into groups according pathological features (60 DN group 50 NDRD group). Clinical...

10.1093/ndt/gfm897 article EN Nephrology Dialysis Transplantation 2007-12-22

We recently found that polyunsaturated lecithin prevents ethanol from causing cirrhosis in the baboon. Because transformation of lipocytes to transitional cells plays a key role hepatic fibrogenesis vivo, and because this process alcohol-fed baboons was be attenuated by lecithin, we focused on study mechanism protective effect. Rat cultured plastic undergo spontaneous activation, accompanied expression α-smooth muscle actin isoform production substantial amounts type I collagen. The latter...

10.1002/hep.1840150303 article EN Hepatology 1992-03-01

Aim. To evaluate the relation of proprotein convertase subtilisin-kexin type 9 (PCSK9) levels to coronary artery disease (CAD).

10.3109/07853890.2015.1042908 article EN Annals of Medicine 2015-07-04

Familial hypercholesterolemia (FH) is characterized by an elevated low-density lipoprotein cholesterol and increased risk of premature coronary artery disease. However, the general picture mutational spectrum FH in China are far from recognized, representing a missed opportunity for investigation.A total 8050 patients undergoing angiography were enrolled. The diagnosis clinical was made using Dutch Lipid Clinic Network criteria, information relatives obtained inquiring probands or their own...

10.1161/atvbaha.116.308456 article EN Arteriosclerosis Thrombosis and Vascular Biology 2016-12-09
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