Osman Açıkgöz

ORCID: 0000-0003-1444-5847
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About
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Research Areas
  • Stress Responses and Cortisol
  • Exercise and Physiological Responses
  • Tryptophan and brain disorders
  • Adipose Tissue and Metabolism
  • Muscle metabolism and nutrition
  • Circadian rhythm and melatonin
  • Anesthesia and Neurotoxicity Research
  • Diverse Legal and Medical Studies
  • Legal Issues in Turkey
  • Vitamin C and Antioxidants Research
  • Sleep and related disorders
  • Neurotransmitter Receptor Influence on Behavior
  • Impact of Technology on Adolescents
  • Sports Performance and Training
  • Neuroscience and Neuropharmacology Research
  • Cultural and Sociopolitical Studies
  • Turkish Urban and Social Issues
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Child Development and Digital Technology
  • Public Administration and Governance
  • Mitochondrial Function and Pathology
  • Biochemical effects in animals
  • Dialysis and Renal Disease Management
  • Neuroendocrine regulation and behavior
  • Sports Analytics and Performance

Dokuz Eylül University
2005-2024

Istanbul 29 Mayis University
2024

We have previously shown that erythropoietin (Epo) exerts neuroprotective effects in the Rice-Vannucci model of neonatal hypoxic-ischemic brain injury. However, mechanisms Epo protection this are still unclear.In present study, we studied systemically administered on lipid peroxidation levels and antioxidant enzyme (superoxide dismutase glutathione peroxidase) activities following injury rats.Seven-day-old Wistar rat pups were subjected to left carotid artery occlusion followed by 2.5 h...

10.1159/000080490 article EN Neonatology 2004-09-15

Background: Sleep quality plays a principal role in the protection of health. There is an increasing number studies literature demonstrating that internet addiction and smartphone impair sleep quality. However, on Turkish adolescents very limited. Therefore, this study examined effects among adolescents. Methods: Participants cross-sectional were 910 aged 13-18 years. Data collected with Short Internet Addiction Test, Smartphone Scale, Pittsburgh Quality Index. In addition, questionnaire was...

10.7717/peerj.12876 article EN cc-by PeerJ 2022-02-02

Progressive compromise of antioxidant defenses and free radical-mediated lipid peroxidation, which is one the major mechanisms secondary traumatic brain injury (TBI), has also been reported in pediatric head trauma. In present study, we aimed to demonstrate effect melatonin, a potent radical scavenger, on oxidative damage 7-day-old rat pups subjected contusion injury. Whereas TBI significantly increased thiobarbituric acid reactive substances (TBARS) levels, there was no compensatory...

10.33549/physiolres.930709 article EN cc-by-nc Physiological Research 2005-01-01

Melatonin has recently been suggested as an antioxidant that may protect neurons from oxidative stress. Acute ethanol administration produces both lipid peroxidation indicator of stress in the brain and impairs water-maze performance spatial learning memory tasks. The present study investigated effect melatonin against ethanol-induced impairment. Morris water maze was used to evaluate cognitive functions rats. Thiobarbituric acid reactive substances (TBARS), which are indicators...

10.33549/physiolres.930639 article EN cc-by-nc Physiological Research 2005-01-01

In anaemia of chronic renal failure, the most important factor in shortened erythrocyte survival may be lipid peroxidation cell membrane. Defective antioxidant activity increase this damage. Although recombinant human erythropoietin (r-HuEPO) can effectively correct haemodialysis patients, its actions on and are not clear. These were investigated 13 patients undergoing haemodialysis. Antioxidant activity, including red blood superoxide dismutase total glutathione peroxidase levels product...

10.3109/00365599709030622 article EN Scandinavian Journal of Urology and Nephrology 1997-01-01

Also known as programmed cell death, apoptosis is a sequence of events that leads to elimination cells without releasing harmful substances into the surrounding area. Apoptosis may be induced by intracellular or extracellular signals. Certain apoptotic signals activate mitochondrial pro-apoptotic and increase reactive oxygen species (ROS). Increased ROS production lead oxidative stress. The goal our study was characterize age-related changes in stress hippocampus. Rats 2, 7, 21 38 days old,...

10.3109/10520295.2011.556665 article EN Biotechnic & Histochemistry 2011-01-31

It is known that regular aerobic exercise enhances cognitive functions and increases blood insulin-like growth factor 1 (IGF-1) levels. People living in urban areas spend most of their time indoors indoor air quality can affect health. We investigated the effects poor good environments on hippocampus prefrontal cortex (PFC) neurons, anxiety, spatial learning memory adolescent mice. Poor impaired memory; did not or impairment. Exercise a environment improved memory. increased apoptosis PFC....

10.3109/10520295.2013.825318 article EN Biotechnic & Histochemistry 2013-09-20

Background/aim: Mesenchymal stem cells (MSCs) are a type of adult cell consisting heterogeneous subset stromal that can be isolated from tissues. Folic acid is another important contributor to tissue regeneration and repair, which affects the synthesis some building block molecules used for wound healing. In this study, we examine effect folic MSC-derived soluble factors in healing model.Materials methods: Human umbilical vein endothelial (HUVECs) bone marrow-derived MSCs (BMSCs) were...

10.3906/sag-1901-231 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2019-06-18

Professional athletes competing in the NBA are frequently exposed to time-zone-shifting travels. These time zone changes may cause circadian rhythm (CR) phase shifts and these affect sportive performance. The aim of this study was investigate effects CR on performance teams. 25016 regular season games across 21 consecutive seasons were included shift calculations. To examine effect team performance, teams divided into three groups regarding Coordinated Universal Time (UTC): same internal UTC...

10.1080/07420528.2024.2325641 article EN other-oa Chronobiology International 2024-04-30

In a previous study we demonstrated that acute footshock stress increased glutathione peroxidase activity in the prefrontal cortex and striatum of adult male rats. Adolescents may respond differently to as life stressors be greater than at other ages. The present examined effects on superoxide dismutase (SOD) (GPx) enzyme activities thiobarbituric acid reactive substances (TBARS) levels adolescent female rat brains. We SOD cortex, GPx hippocampus males, hippocampus. Footshock did not change...

10.33549/physiolres.930632 article EN cc-by-nc Physiological Research 2005-01-01
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