A5080388503- Tuberculosis Research and Epidemiology
- Thyroid Disorders and Treatments
- Neonatal Respiratory Health Research
- Rheumatoid Arthritis Research and Therapies
- Pneumonia and Respiratory Infections
- Liver Disease Diagnosis and Treatment
- Renal Transplantation Outcomes and Treatments
- Coronary Interventions and Diagnostics
- Diabetes and associated disorders
- Congenital Diaphragmatic Hernia Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Autoimmune and Inflammatory Disorders Research
- Acute Myocardial Infarction Research
- Growth Hormone and Insulin-like Growth Factors
- Cardiac Imaging and Diagnostics
- Infant Nutrition and Health
- Suicide and Self-Harm Studies
- Interpreting and Communication in Healthcare
- T-cell and B-cell Immunology
- Mental Health and Patient Involvement
- Complement system in diseases
- Emergency and Acute Care Studies
- Lipid metabolism and disorders
- Delphi Technique in Research
- Global Cancer Incidence and Screening
Universidade do Porto
2013-2025
University of Lisbon
2025
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2023-2025
National Heart Lung and Blood Institute
2024
Hospital de São João
2002-2020
Various cytokines have been associated to the occurrence of bronchopulmonary dysplasia (BPD) in preterm neonates.To establish an association between cord blood and BPD, so that they could be used, clinical practice, as early markers BPD.Preterms less than 30 weeks gestational age, were analysed by ELISA microassay for venous IL-1β, IL-6, IL-8, TNF-α IL-10, compared BPD non-BPD groups.One hundred fifty neonates completed study; 31 (21%) small age (SGA); 16 deceased before 28 days life; 36...
Introduction : Various cytokines have been associated to the occurrence of bronchopulmonary dysplasia (BPD) in preterm neonates. AIM To establish an association between cord blood and BPD, so that they could be used, clinical practice, as early markers BPD. Material methods Preterms less than 30 weeks gestational age, were analysed by ELISA microassay for venous IL-1 β , IL-6, IL-8, TNF- α IL-10, compared BPD non-BPD groups. Results One hundred fifty neonates completed study; 31 (21%) small...
People with or affected by tuberculosis (TB) experience complex social and cultural constraints that may affect treatment outcomes impeding access to proper care hindering adherence. Low levels of health literacy which leads inadequate disease information; stigma, discrimination other forms prejudice result in marginalisation ostracisation; socioeconomic vulnerabilities hamper one's capacity essential goods increase the risk exposure are some barriers highlighted. These hurdles also...
Objectives To translate and culturally adapt an English language patient decision aid addressing prostate cancer screening, so it can be used by Portuguese men. Design Qualitative study. We followed the European Centre for Disease Prevention Control’s (ECDC) five-step, stakeholder-based approach to adapting health communication materials: (1) selection of materials process coordinators, (2) early review, (3) translation back translation, (4) comprehension testing with cognitive...
Hospital readmissions are associated with increased healthcare expenses and higher hospital fatality rates. We aim to characterize unplanned occurred within 30 days after discharge, according its Major Diagnosis Category, type location, patients' demographic attributes. also intend estimate the rates those readmissions, as well study evolution of in last decade (2000-2008). Moreover, we heart failure readmissions.We analysed a database (provided by Autoridade Central do Sistema de Saúde)...
Background. The new cyclosporin (CsA) formulation, Neoral®, has different pharmacokinetics compared with Sandimmune® (SIM). Larger area under the curve (AUC) values equivalent trough blood are reached when Neoral is administered at doses to SIM. Previously, we showed a great diagnostic reliability using cytofluorometric analysis from fine‐needle aspiration biopsy (FNAB) samples. We investigated possible changes brought about by on lymphocyte subsets and repercussions activation score cut‐off...
Focal segmental glomerulosclerosis (FSGS) aetiology remains undefined although a derangement of lymphocytes and monocytes macrophages, at least, has been strongly suspected. We report the graft-infiltrating phenotypes their cytokine production in case FSGS recurrence post-transplantation.The kidney transplant recipient suffered immediate recurrence. Aspiration biopsies were done first second week post-surgery analysed by flow cytometry. The analysis was on aspiration sample culture...
Regadenoson is used to induce hyperemia in cardiac imaging, facilitating diagnosis of ischemia and assessment coronary flow reserve (CFR). While the regadenoson package insert recommends administration radionuclide tracer 10-20 seconds after injection, peak has been observed at approximately 100 injection healthy volunteers undergoing cardiovascular magnetic resonance imaging (CMR). It unclear when occurs a patient population. The goal this study was determine time patients, whether...
Patient-reported outcomes (PROs) play a crucial role in understanding the impact of tuberculosis (TB) on both individuals and communities. Despite advances TB treatment, conventional outcome definitions often overlook essential components people with TB's experiences, leading to disparities treatment understanding. The incorporation PROs scientific research can help bridge gap between health system people's needs expectations. offer valuable insights into non-observable constructs like...
Objective: The demanding nature and psychosocial burdens of directly observed treatment (DOT) have opened a path to alternative strategies such as video-observed therapy (VOT), which offers comparable outcomes patient satisfaction while potentially saving time reducing costs. objective this study was evaluate the perceptions experiences patients health care professionals regarding DOT other implemented in Portugal. Methods: Patients with confirmed diagnosis tuberculosis, treated at Vila Nova...
Language plays a crucial role in shaping discourses and responses related to disease, particularly tuberculosis (TB). Stigmatising language attitudes surrounding TB can lead discrimination marginalisation of affected individuals, creating barriers seeking proper diagnosis treatment. The terminology used describe TB-affected individuals be disempowering criminalising, reinforcing an “othering” those affected. To combat this, engaging with communities is essential co-construct neutral...
<i>Background/Aims:</i> Growth of T cell lines from kidney graft biopsy specimens that suppress the antidonor response, either directly or through a soluble factor, both specific and nonspecific to donor, has been reported. Fine-needle aspiration sample cultures synthesize large array cytokines/chemokines with significant differences between stable versus acute rejection transplants. We hypothesize products such may be endowed response modulation abilities in transplantation....
There is still a lack of health indicators for monitoring and evaluating planning at the local level. In Portugal, plans (LHP) include prioritized set priorities, which should be monitored evaluated. This study an example low-resource method to identify reuse LHP evaluation already collected other purposes.A modified Delphi consensus was applied, with three rounds email rating questionnaires final meeting, between January 2018 2019. The panel consisted eight members from Planning...