A5037972450- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical studies and practices
- Health Systems, Economic Evaluations, Quality of Life
- Tuberculosis Research and Epidemiology
- Antibiotics Pharmacokinetics and Efficacy
- Cardiac Imaging and Diagnostics
- Pharmaceutical Economics and Policy
- Acute Myocardial Infarction Research
- Antibiotic Use and Resistance
- Cardiovascular Function and Risk Factors
- Pneumonia and Respiratory Infections
- Patient Safety and Medication Errors
- Pharmacovigilance and Adverse Drug Reactions
- Retinal and Optic Conditions
- Mycobacterium research and diagnosis
- Pharmacological Effects and Toxicity Studies
- Nitric Oxide and Endothelin Effects
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Nausea and vomiting management
- Infectious Diseases and Tuberculosis
- Pharmacy and Medical Practices
- Pharmaceutical industry and healthcare
- Gastric Cancer Management and Outcomes
- Drug Transport and Resistance Mechanisms
Clinica Universidad de Navarra
2014-2025
Hospital Clínico San Carlos
2024
Hospital de Sant Joan Despí Moisès Broggi
2023
Services Hospital
2022
Biomedical Research Institute
2022
INCLIVA Health Research Institute
2022
Hospital Clínico Universitario Virgen de la Victoria
2021
Universidad de Navarra
1998-2020
Hospital General Universitario Gregorio Marañón
1997-2011
Hospital Universitario Severo Ochoa
2011
Progress in understanding the basis of resistance to isoniazid (INH) and rifampin (RMP) has allowed molecular tests for detection drug-resistant tuberculosis be developed. Consecutive isolates (n = 95) Mycobacterium tuberculosis, from a Spanish reference laboratory investigating outbreaks multidrug-resistant were coded sent two external laboratories genotypic analysis INH RMP by PCR-single-strand conformation polymorphism (SSCP) specific regions four genes: part coding sequence katG promoter...
The purpose of this study was to determine the extent transmission tuberculosis in a large prison population over an 18-mo period. Restriction-fragment-length polymorphism (RFLP) analysis isolates Mycobacterium performed, using insertion sequence IS6110 and plasmid pTBN12. Patients infected with strains having same fingerprint were grouped clusters. Medical records reviewed movement inmates among prisons examined for selected patients. Tuberculosis diagnosed 216 (case rate = 2,283 per...
La fuerza muscular es esencial para la funcionalidad y calidad de vida en adultos mayores, particularmente aquellos con sarcopenia, una condición asociada al envejecimiento que conlleva pérdida progresiva masa muscular. El objetivo esta revisión fue evaluar los efectos del entrenamiento restricción parcial flujo sanguíneo (BFR) mayores sarcopenia. búsqueda identificó 4 ensayos clínicos controlados cumplían criterios inclusión un total 147 participantes, demostraron consistentemente el BFR...
In 2023, the General Directorate of Pharmacy Ministry Health commissioned Advisory Committee on Financing Pharmaceuticals for National System (CAPF, Comité Asesor para la Financiación de Prestación Farmacéutica del Sistema Nacional Salud) to produce a guideline evaluation efficiency medicines. The aim this methodological note is present their main points. includes 17 dimensions that an economic medicines must encompass, design reference case, and checklist evaluating quality reporting. This...
Anemia, one of the most common complications cancer chemotherapy, has been managed with red blood cell (RBC) transfusions. As an alternative, agent epoetin alfa potential to reduce transfusion requirements patients receiving chemotherapy. To estimate value that place on drug, economic analysis using concept willingness pay (WTP) was conducted.The method WTP used within framework a classical cost-benefit net cost or benefit administering prophylactic patients. This included direct...
In this study we compared the efficacy and safety of three antiemetic combinations in prevention postoperative nausea vomiting (PONV). Ninety ASA status I–II women, aged 18–65 yr, undergoing general anesthesia for major gynecological surgery, were included a prospective, randomized, double-blinded study. A standardized anesthetic technique analgesia (intrathecal morphine plus IV patient-controlled (PCA) with morphine) used all patients. Patients randomly assigned to receive ondansetron 4 mg...
Adverse drug reaction (ADR) spontaneous reporting is the primary method of postmarketing surveillance; although it an important part surveillance, underused. Before 2004, almost no ADRs were reported in our 400-bed hospital. As electronic hospital information system was available hospital, we developed a tool (ADR-RS-IHIS) for ADR integrated into to facilitate through easy use, automatic input certain information, increased accessibility, real-time review, and intervention.To analyze...
OBJECTIVE: To report a case of delayed elimination high-dose methotrexate (MTX) associated with concomitant omeprazole administration. CASE SUMMARY: Delayed MTX was observed in an 11-year-old white boy who concomitantly received and omeprazole. The patient's serum creatinine liver function tests were normal during treatment follow-up. only medication we suspected inhibiting 20 mg every 12 hours. Twenty-four hours after the first cycle (15 g), discontinued. Thereafter, patient one without...