A5019031962- Parasitic Diseases Research and Treatment
- Research on Leishmaniasis Studies
- Parasites and Host Interactions
- Mathematical and Theoretical Epidemiology and Ecology Models
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Plant and animal studies
- Parasite Biology and Host Interactions
- Evolution and Genetic Dynamics
- Insect and Arachnid Ecology and Behavior
- Insects and Parasite Interactions
- Insect symbiosis and bacterial influences
- Insect Pheromone Research and Control
- Trypanosoma species research and implications
- Zoonotic diseases and public health
- Insect and Pesticide Research
University of South Florida
2020-2024
Center for Global Health
2020-2024
University of Oxford
2022
Erasmus MC
2022
Swiss Tropical and Public Health Institute
2022
University of Basel
2022
Radboud University Nijmegen
2022
Radboud University Medical Center
2022
University of Warwick
2022
Imperial College London
2022
Abstract Due to the COVID-19 pandemic, many key neglected tropical disease (NTD) activities have been postponed. This hindrance comes at a time when NTDs are progressing towards their ambitious goals for 2030. Mathematical modelling on several NTDs, namely gambiense sleeping sickness, lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminthiases (STH), trachoma, and visceral leishmaniasis, shows that impact of this disruption will vary across diseases. Programs face...
Abstract Background In view of the current global coronavirus disease 2019 pandemic, mass drug administration interventions for neglected tropical diseases, including lymphatic filariasis (LF), have been halted. We used mathematical modelling to estimate impact delaying or cancelling treatment rounds and explore possible mitigation strategies. Methods three established LF transmission models simulate infection trends in settings with annual programme delays 2020 6, 12, 18 24 months. then...
Abstract Background Lymphatic filariasis (LF) is a debilitating, poverty-promoting, neglected tropical disease (NTD) targeted for worldwide elimination as public health problem (EPHP) by 2030. Evaluating progress towards this target national programmes challenging, due to differences in transmission and interventions at the subnational level. Mathematical models can help address these challenges capturing spatial heterogeneities evaluating LF how different could be leveraged achieve Methods...
Abstract Background Lymphatic filariasis (LF) is a neglected tropical disease targeted for elimination as public health problem by 2030. Although mass treatments have led to huge reductions in LF prevalence, some countries or regions may find it difficult achieve 2030 owing various factors, including local differences transmission. Subnational projections of intervention impact are useful tool understanding these dynamics, but correctly characterizing their uncertainty challenging. Methods...
Male and female moths communicate in complex ways to search for select a mate. In process termed calling, females emit small quantities of pheromones, generating plumes that spread the environment. Males detect plume through their antennae navigate toward female. The reproductive is marked by choice male–male competition, since multiple males aim reach but only first can mate with her. This provides an opportunity selection on male traits such as chemosensitivity pheromone molecules...
Background Mass drug administration (MDA) is the main strategy towards lymphatic filariasis (LF) elimination. Progress monitored by assessing microfilaraemia (Mf) or circulating filarial antigenaemia (CFA) prevalence, latter being more practical for field surveys. The current criterion stopping MDA requires <2% CFA prevalence in 6- to 7-year olds, but this not evidence-based. We used mathematical modelling investigate validity of different thresholds regarding testing method and age group...
Quantitative trait loci (QTL) mapping procedures were used to identify that influence the levels of alarm pheromones found in stinging apparatus worker honeybees. An F1 queen was produced from a cross between European origin and drone descended an African subspecies. Haploid drones hybrid individually backcrossed queens produce 172 colonies. Samples stings taken backcross workers these Alarm pheromone determined by gas chromatography. RAPD markers scored haploid fathers The multiple-QTL...
Vector-borne diseases that occur in humans, as well domestic and wild reservoir hosts, cause a significant concern public health, veterinary ecological health bio-diverse environments. The majority of vector-borne zoonotic are transmitted among diverse host species, but different hosts have their own ability to transmit pathogens attract vectors. These combined transmission mechanisms vectors often called "host competencies" "vector-feeding preferences." purpose this research is assess the...
The final goal of control policies in neglected vector‐borne diseases developing countries is to protect humans. These include leishmaniasis, dengue, chagas, and malaria. traditional measures for diseases, as with any other illnesses, suggest reduce the basic reproduction number below value 1. This strategy not necessarily sufficient when a backward bifurcation occurs. Because its worldwide relevance, we are interested modeling cutaneous leishmaniasis Peru specific example. We use...
Vector‐borne diseases, such as leishmaniasis, dengue, malaria, and yellow fever, transmitted by microparasites show periodic fluctuations in their prevalence. The novelty of this research is to assess the relationship between vector feeding preference for an infectious host annual seasonal transmission through a vector‐host mathematical model. For first time, numerical simulations illustrate that increasing value dynamics, accentuate endemic equilibrium average increases populations....
We study a general multi-host model of visceral leishmaniasis including both humans and animals, where host vector characteristics are captured via competence along with biting preference. Additionally, the accounts for spatial heterogeneity in human population behaviour sandflies. then use parameters Indian subcontinent as an example demonstrate that exhibits backward bifurcation, i.e. it has infection sandfly threshold, characterized by bi-stable region. These thresholds shift function...
Abstract Background In view of the current global COVID-19 pandemic, mass drug administration interventions for neglected tropical diseases, including lymphatic filariasis, have been halted. We used mathematical modelling to estimate impact delaying or cancelling treatment rounds and explore possible mitigation strategies. Methods three established filariasis transmission models simulate infection trends in settings with annual programme delays 2020 6, 12, 18 24 months. then evaluated...