A5103143362- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Advanced Machining and Optimization Techniques
- Economic Theory and Policy
- Advanced Sensor Technologies Research
- Surface Roughness and Optical Measurements
- Scientific Measurement and Uncertainty Evaluation
- Advanced machining processes and optimization
- Advanced Surface Polishing Techniques
- Public Health in Brazil
- Agricultural and Food Sciences
- Cancer Cells and Metastasis
- Health, Education, and Aging
- Economic and Technological Innovation
- Palliative and Oncologic Care
- Cancer, Hypoxia, and Metabolism
Centro Universitário Serra dos Órgãos
2019
Marshall University
2014
Administration of ineffective anticancer therapy is associated with unnecessary toxicity and development resistant clones. Cancer stem-like cells (CSLCs) resist chemotherapy, thereby causing relapse the disease. Thus, a test that identifies most effective chemotherapy management offers great promise for individualized treatments. We have developed an ex vivo sensitivity assay (ChemoID), which measures CSLCs as well bulk tumor to variety agents. Two patients, 21-year old male (patient 1)...
e13012 Background: Cancer stem-like cells (CSLCs) in primary brain tumors can resist certain chemotherapies, thereby causing relapse of the disease. Thus, development a test that identifies most effective chemotherapy management offers great promise for personalized anticancer treatments. Methods: We have developed an ex vivo chemosensitivity assay (ChemoID) designed to predict sensitivity and resistance CSLCs bulk tumor given patient's solid variety agents by measuring cellular viability...