A5037031137- Obstructive Sleep Apnea Research
- Sleep and Wakefulness Research
- Neuroscience of respiration and sleep
- Sleep and related disorders
- Respiratory Support and Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Restless Legs Syndrome Research
- Spinal Cord Injury Research
- Parkinson's Disease Mechanisms and Treatments
- Dysphagia Assessment and Management
- Cardiovascular and Diving-Related Complications
- Tracheal and airway disorders
- Quality and Safety in Healthcare
- Network Time Synchronization Technologies
- Stroke Rehabilitation and Recovery
- Context-Aware Activity Recognition Systems
- Renal function and acid-base balance
- Infection Control and Ventilation
- Cardiac Arrest and Resuscitation
- Lung Cancer Diagnosis and Treatment
- Healthcare Systems and Public Health
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Non-Invasive Vital Sign Monitoring
- Hemodynamic Monitoring and Therapy
Institute for Breathing and Sleep
2015-2025
Austin Health
2011-2025
Austin Hospital
2015-2022
Monash Medical Centre
2001-2010
SleepMed
2010
Background:Reduced upper airway muscle activity during sleep is fundamental to obstructive apnea (OSA) pathogenesis. Hypoglossal nerve stimulation (HGNS) counteracts this problem, with potential reduce OSA severity.
Swallowing is closely coordinated with breathing but in COPD altered synchronization may predispose patients to a breach of the upper airway protective mechanisms. However, aspiration during swallow has never been shown COPD. We examined penetration liquid material into and correlated it breathing-swallow patterns.A case-control study was performed. Patients (n = 16) were matched normal control subjects 15). Sub-mandibular videofluoroscopy carried out graduated volumes barium detect...
Background: Pulse oximetry is a common technique used to measure SpO2, with increasing numbers of portable devices different designs and technical specifications. This study examined accuracy commercial medical-grade (BioBeat wristwatch, Nonin WristOx2 3150, Heart Sure A320) in measuring SpO2 compared the reference standard (Masimo Rad-5) during 6-min walk tests (6MWTs). Methods: prospective included 50 subjects, 10 recruited for each five target groups, including COPD, interstitial lung...
To determine the effect of mild vs severe Parkinson's disease on objective sleep parameters, in a subgroup patients with subjective excessive daytime somnolence.Patients either (Hoehn and Yahr stage 1 or 2) 4 5) idiopathic evidence sleepiness (Epworth scale > 8) were recruited. All underwent overnight polysomnography autonomic function testing completed questionnaires assessing quality life, mood, drug dosages. Mild groups then compared using paired t-test for normally distributed data...
Patients with obstructive sleep apnea (OSA) experience respiratory events greater frequency and severity while in the supine sleeping position. Postural modification devices (PMDs) prevent sleep, although there is a paucity of guidance to help clinicians decide when use PMDs for their patients. In order treat OSA effectively, patients must position consistently from night have low nonsupine hypopnea index (AHINS).To document repeatability traditionally defined predominant on consecutive...
Background Obstructive sleep apnoea (OSA) is highly prevalent in people with spinal cord injury (SCI). Polysomnography (PSG) the gold-standard diagnostic test for OSA, however PSG expensive and frequently inaccessible, especially SCI. A two-stage model, incorporating a questionnaire followed by oximetry, has been found to accurately detect moderate severe OSA (MS-OSA) non-disabled primary care population. This study investigated accuracy of model chronic tetraplegia using both original...
Abstract Study Objectives Over 80% of people with tetraplegia have sleep-disordered breathing (SDB), but whether this is predominantly obstructive or central unclear. This study aimed to estimate the prevalence sleep apnea (CSA) in and contributions central, obstructive, hypopnea respiratory events SDB summary indices tetraplegia. Methods Research clinical data from 606 individuals full overnight polysomnography were collated. The proportions different event types calculated; overall for...
Home polysomnography (PSG) is an alternative method for diagnosis of obstructive sleep apnoea (OSA). Some types 3 and 4 PSG do not monitor so rely on patients' estimation total time (TST).To compare subjective duration with objective measures in patients who underwent type 2 probable OSA.A prospective clinical audit 536 consecutive one the authors between 2006 2013. A standard questionnaire was completed by morning after home to record lights being turned off estimated onset offset. scored...
ABSTRACT Background and objective: OSA is a common disorder resulting in health economic burdens. Currently identifying patients involves expensive techniques that require overnight studies laboratory setting with qualified staff. This paper tests new acoustic device (AirwayClear (AC)) for assessing upper airway patency human subjects OSA. We hypothesize obstructive apnoeas would be detected equally well AC polysomnography (PSG). Methods: Twenty‐three severe underwent an CPAP titration...
For clinicians involved in investigating and treating sleep disorders, understanding the accuracy of patient recall supine would allow informed comparisons between polysomnography (PSG) patient-reported patients with supine-predominant obstructive apnea. This study aims to assess perception sleep.Prospective observational cohort study, assessing total sleep, including duration. Data were analyzed utilizing descriptive statistics, bias-plot (Bland-Altman) analysis, Spearman correlation (rs)...
Sleep-wake dysfunction is bidirectionally associated with the pathogenesis and evolution of stroke. Longitudinal prospective measurement sleep after chronic stroke remains poorly characterized because a lack validated objective ambulatory tools in neurological populations. This study aimed to validate multisensor monitor, SenseWear Armband (SWA), patients ischemic control using at-home polysomnography.Twenty-eight radiologically confirmed (aged 69.61 ± 7.35 years; mean = 4.1 years...
P.R. Eastwood, PhD, M. Barnes, MBBS, R.D. McEvoy, J. Wheatley, J.H. Walsh, F.J. O'Donoghue, MB BCh FRACP MRCP P. Catcheside, L. Tyler, BN, K.J. Maddison, BSc, P.D. Rochford, BApSc, N. Antic, C. Worsnop, MD, T. Churchward, B Ap Sc, D.J. Eckert, M.C. Campbell, MB, BS, FRACS, G. Hee, C.E. Palme, S.H. Robinson, E. Kezirian, Goding, A.S. Jordan, P.L. Smith, A.R. Schwartz, A. Malhotra, D.R. Hillman, MD Sir Charles Gairdner Hospital Perth/AU, Austin Melbourne/AU, Repatriation General Adelaide/AU,...
The oxygen desaturation index (ODI) is an important measure of sleep-disordered breathing during polysomnography (PSG); however, the AASM Manual (V3) does not specify whether to include desaturations occurring wake epochs. Additionally, ODI obtained from PSG can differ using home sleep apnea tests (HSATs) that do sleep, hampering diagnostic and treatment decision reliability. This study aimed (1) compare included all with excluded epochs in (2) ODIs HSAT.
Venous blood gases (VBGs) are not consistently considered suitable surrogates for arterial (ABGs) in assessing acute respiratory failure due to variable measurement error. The physiological stability of patients with chronic ventilatory may lead improved agreement this setting.
Abstract Introduction/Background Accurate body position measurement is used for diagnosing and managing obstructive sleep apnoea (OSA). Typically, sensor data are corrected by experts using video recordings, but this unavailable during unattended polysomnography (PSG). It thus important to understand the accuracy of sensors. Aim To evaluate correction rates measurements PSG in a clinical laboratory setting. Methods We analysed 30 consecutive PSGs, all with conducted adults being assessed...
Abstract Background Ventilator performance has been shown to vary across conditions, ventilator type, and in common scenarios such as mask leak. Aim: This study sought compare the of a Breas Medical AB (Mölnlycke, Sweden) Vivo 45 LS™ ResMed (San Diego, CA, USA) Lumis™ ventilator. Methods Pressure, flow volume waveforms were sampled for each at analogous settings, under three simulated clinical conditions using an ASL5000™ (Ingmar Medical, Pittsburgh, PA, respiratory simulator: (A)...
Abstract Background The Victorian Respiratory Support Service (VRSS) provides long-term management for patients with chronic respiratory failure. An expanding patient base (497 in 2000, 2,031 2024) necessitates service development. Integration of non-invasive ventilator (NIV) data from ResMed Airview™ (San Diego, CA, USA) presented an opportunity to review these at a “whole service” level. Aim To pilot summarised, visualisation system the VRSS. Methods were ingested daily into hospital...
There is an internal contradiction in current American Academy of Sleep Medicine standards for arousal index (AI) calculation polysomnography: Arousals sleep and wake epochs are counted, but only time used the denominator. This study aimed to investigate impact including arousals scored on AI.We compared AIs (AIinc) vs excluding (AIexc) awake-epoch from 100 consecutive polysomnograms conducted investigation possible obstructive apnea. To determine AI that most closely approximated "truth,"...