William Martin

ORCID: 0000-0003-1478-6449
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About
Contact & Profiles
Research Areas
  • Genomics and Phylogenetic Studies
  • Protist diversity and phylogeny
  • Photosynthetic Processes and Mechanisms
  • Microbial Community Ecology and Physiology
  • Origins and Evolution of Life
  • Mitochondrial Function and Pathology
  • Microbial Metabolic Engineering and Bioproduction
  • RNA and protein synthesis mechanisms
  • Occupational Health and Safety Research
  • Risk and Safety Analysis
  • Chemical Safety and Risk Management
  • Algal biology and biofuel production
  • Methane Hydrates and Related Phenomena
  • Chromosomal and Genetic Variations
  • Enzyme Structure and Function
  • Parasitic Infections and Diagnostics
  • Legume Nitrogen Fixing Symbiosis
  • Bacteriophages and microbial interactions
  • Marine Biology and Ecology Research
  • Muscle metabolism and nutrition
  • Genetic diversity and population structure
  • Insect symbiosis and bacterial influences
  • Animal Genetics and Reproduction
  • Plant Diversity and Evolution
  • Genetics, Bioinformatics, and Biomedical Research

Heinrich Heine University Düsseldorf
2016-2025

Fundación Universitaria del Área Andina
2024

University of Cincinnati
2024

Turner-Fairbank Highway Research Center
2024

Leidos (United States)
2024

Hochschule Düsseldorf University of Applied Sciences
2023

Eunice Kennedy Shriver National Institute of Child Health and Human Development
2012-2022

National Institutes of Health
2022

University of Guelph
2021

Bridge University
2021

Chloroplasts were once free-living cyanobacteria that became endosymbionts, but the genomes of contemporary plastids encode only ≈5–10% as many genes those their cousins, indicating either lost from or transferred to nucleus during course plant evolution. Previous estimates have suggested between 800 and perhaps 2,000 in Arabidopsis genome might come cyanobacteria, genome-wide phylogenetic surveys could provide direct this number are lacking. We compared 24,990 proteins encoded three...

10.1073/pnas.182432999 article EN Proceedings of the National Academy of Sciences 2002-09-06

The complete sequence of the 1,267,782 bp genome Wolbachia pipientis wMel, an obligate intracellular bacteria Drosophila melanogaster, has been determined. Wolbachia, which are found in a variety invertebrate species, great interest due to their diverse interactions with different hosts, range from many forms reproductive parasitism mutualistic symbioses. Analysis wMel genome, particular phylogenomic comparisons other bacteria, revealed insights into biology and evolution general. For...

10.1371/journal.pbio.0020069 article EN cc-by PLoS Biology 2004-03-09

All life is organized as cells. Physical compartmentation from the environment and self–organization of self–contained redox reactions are most conserved attributes living things, hence inorganic matter with such would be life's likely forebear. We propose that evolved in structured iron monosulphide precipitates a seepage site hydrothermal mound at redox, pH temperature gradient between sulphide–rich fluid iron(II)–containing waters Hadean ocean floor. The naturally arising,...

10.1098/rstb.2002.1183 article EN Philosophical Transactions of the Royal Society B Biological Sciences 2003-01-29

Isopentenyl diphosphate (IPP) is the central intermediate in biosynthesis of isoprenoids, most ancient and diverse class natural products. Two distinct routes IPP occur nature: mevalonate pathway recently discovered deoxyxylulose 5-phosphate (DXP) pathway. The evolutionary history enzymes involved both phylogenetic distribution their genes across genomes suggest that germane to archaebacteria, DXP eubacteria, eukaryotes have inherited for from prokaryotes. occurrence specific restricted...

10.1073/pnas.240454797 article EN Proceedings of the National Academy of Sciences 2000-11-14

Chloroplasts were once free-living cyanobacteria, mitochondria proteobacteria, and both have preserved remnants of eubacterial genomes. But from the functional standpoint, organelles retained much more their biochemistry than is reflected in DNA.

10.1104/pp.118.1.9 article EN PLANT PHYSIOLOGY 1998-09-01

The natural transfer of DNA from mitochondria to the nucleus generates nuclear copies mitochondrial (numts) and is an ongoing evolutionary process, as genome sequences attest. In humans, five different numts cause genetic disease a dozen human loci are polymorphic for presence numts, underscoring rapid rate at which reach over time. laboratory in nature, enter via non-homolgous end joining (NHEJ) double-strand breaks (DSBs). frequency numt insertions among 85 sequenced eukaryotic genomes...

10.1371/journal.pgen.1000834 article EN cc-by PLoS Genetics 2010-02-11

For life to have emerged from CO₂, rocks, and water on the early Earth, a sustained source of chemically transducible energy was essential. The serpentinization process is emerging as an increasingly likely that energy. Serpentinization ultramafic crust would continuously supplied hydrogen, methane, minor formate, ammonia, well calcium traces acetate, molybdenum tungsten, off-ridge alkaline hydrothermal springs interfaced with metal-rich carbonic Hadean Ocean. Silica bisulfide were also...

10.1111/j.1472-4669.2010.00249.x article EN Geobiology 2010-06-21

Lateral gene transfer is an important mechanism of natural variation among prokaryotes, but the significance its quantitative contribution to genome evolution debated. Here, we report networks that capture both vertical and lateral components evolutionary history 539,723 genes distributed across 181 sequenced prokaryotic genomes. Partitioning these by eigenspectrum analysis identifies community structure in gene-sharing networks, modules which do not correspond a strictly hierarchical...

10.1073/pnas.0800679105 article EN Proceedings of the National Academy of Sciences 2008-07-17

Numerous island-inhabiting species of predominantly herbaceous angiosperm genera are woody shrubs or trees. Such "insular woodiness" is strongly manifested in the genus Echium, which continental circummediterranean distribution herbaceous, whereas endemic islands along Atlantic coast north Africa perennial shrubs. The history 37 Echium was traced with 70 kb noncoding DNA determined from both chloroplast and nuclear genomes. In all, 239 polymorphic positions 137 informative sites, addition to...

10.1073/pnas.93.21.11740 article EN Proceedings of the National Academy of Sciences 1996-10-15

10.1016/j.cell.2012.11.050 article EN publisher-specific-oa Cell 2012-12-01
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