A5100353633- Circular RNAs in diseases
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- RNA Research and Splicing
- Infective Endocarditis Diagnosis and Management
- Streptococcal Infections and Treatments
- Bacterial Identification and Susceptibility Testing
Hainan Medical University
2022
Hainan General Hospital
2022
Wuhan Sixth Hospital
2021
Zhejiang University
2008
Circular RNAs are a large class of noncoding RNA that have shown huge capabilities as gene regulators. Recent evidence suggest circular associated with many diseases, especially cancer. However, little attention has been focused on the expression and function in gastric cancer (GC). In this study, we demonstrate circ-104916 is downregulated GC tissues cell lines. A lower appeared deeper invasion depth, higher tumor stage more frequent lymphatic metastasis patients. Overexpression effectively...
To study the relationship between circular RNA vesicle-associated membrane protein-associated protein A (circVAPA) and pathogenesis of oral squamous cell carcinoma.The expression circVAPA was detected by RT-qPCR. In vitro loss-of-function experiments were performed in Cal-27 cells. The malignant phenotype cells evaluated counting kit-8, clone formation transwell assays. Luciferase reporter assays used to assess circVAPA/miR-132/homeobox (HOXA) regulatory axis.circVAPA significantly increased...
Background: Esophageal carcinoma remains one of the most prevalent malignancies worldwide and has a poor prognosis. squamous cell (ESCC) is predominant type esophageal in Eastern Asia. The predilection site biological behavior ESCC differ from those adenocarcinoma among patients Western countries, indicating that distinctive oncogenesis mechanism. There are only few studies reporting role circular RNAs (circRNAs) molecular mechanisms ESCC. purpose this study was to identify specific circRNAs...
Background: Esophageal carcinoma remains one of the most prevalent malignancies worldwide and has a poor prognosis. squamous cell (ESCC) is predominant type esophageal in Eastern Asia. The predilection site biological behavior ESCC differ from those adenocarcinoma among patients Western countries, indicating that distinctive oncogenesis mechanism. There are only few studies reporting role circular RNAs (circRNAs) molecular mechanisms ESCC. purpose this study was to identify specific circRNAs...
lished information from Zhang's study is somewhat limited, it seems likely that effective antibiotic therapy (colistin, tigecycline, piperacillin/tazobactam, amikacin, etc.) could have been employed for at least some of the infections.Treatment significant systemic infections usually has a better outcome when appropriate antibiotics are administered as early possible [2-5].Continuing with an agent known to in vitro resistance pathogen while withholding treatment susceptibility appears us not...