- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Donation and Transplantation
- Hepatitis B Virus Studies
- Adrenal and Paraganglionic Tumors
- Organ and Tissue Transplantation Research
- Transplantation: Methods and Outcomes
- Neuroendocrine Tumor Research Advances
- Medical Imaging and Pathology Studies
- Blood groups and transfusion
- Clinical Nutrition and Gastroenterology
- Cancer Diagnosis and Treatment
- Metabolism and Genetic Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Parvovirus B19 Infection Studies
- Hepatitis C virus research
- Lung Cancer Research Studies
- Cytomegalovirus and herpesvirus research
- Congenital Anomalies and Fetal Surgery
- Liver physiology and pathology
- Pericarditis and Cardiac Tamponade
- Anorectal Disease Treatments and Outcomes
Klinička bolnica Merkur
2010-2024
University Hospital Centre Zagreb
2020
University of Zagreb
2013-2019
To investigate the potential value of use fibrin glue-antibiotic mixture in treatment anal fistulae.This study included 69 patients with idiopathic nonspecific fistulae. Patients IBD (inflammatory bowel disease), TBC, actinomycosis, and cancer were excluded from study. The microbiological analysis discharge fistula was done routinely. If there any doubt about vertical classification fistulous tract MR canal necessary. As regards disposition, 39 fistulae classified as intersphincteric 30...
In patients with hepatocellular carcinoma (HCC) meeting the Milan criteria (MC), benefit of locoregional therapies (LRTs) in context liver transplantation (LT) is still debated. Initial biases selection between treated and untreated have yielded conflicting reported results. The study aimed to identify, using a competing risk analysis, factors for HCC‐dependent LT failure, defined as pretransplant tumor‐related delisting or posttransplant recurrence. was registered at www.clinicaltrials.gov...
The growing disparity between the rising demand for liver transplantation (LT) and limited availability of donor organs has prompted a greater reliance on older grafts. Traditionally, utilizing livers from elderly donors been associated with outcomes inferior to those achieved grafts younger donors. By accounting additional risk factors, we hypothesize that utilization relatively minor impact both patient survival graft viability.
Chronic transplant dysfunction after kidney transplantation is a major reason of graft loss and caused by immunological non-immunological factors. There evidence that mycophenolate mofetil (MMF) may exert positive effect on renal damage in addition to immunosuppression, its direct antifibrotic properties. The aim our study was retrospectively investigate the role MMF doses progression chronic allograft fibrosis tubular atrophy (IF/TA).Retrospective, cohort study.Patients with tertiary care...
Vasculobiliary injury composed of bile duct, portal vein and hepatic artery is a rare, but the most severe, complication after cholecystectomy that may require hepatectomy or even urgent liver transplantation. We present case 36-year-old Caucasian woman with biliary sepsis large right lobe abscess due to an extreme vasculobiliary laparoscopic cholecystectomy. Bismuth type IV duct injury, thrombosis were identified, resulting in life-threatening septic episodes. Right Roux-en-Y...
Similar to pheochromocytomas, paragangliomas can secrete catecholamines, although they are usually non-functional and clinical presentation is non-specific. We present a case of accidental, intra-operatively diagnosed neuroendocrine-active sympathetic paraganglioma, which was suspected confirmed during elective retroperitoneal tumor removal. A 25-year-old Caucasian Croatian man, American Society Anesthesiologists status 1, underwent surgery for The had been discovered by chance routine...
Donor-origin cancer is a well-recognized but rare complication after liver transplantation (LT). The rise in the use of extended criteria donors due to current shortage organs increases risk. Data on donor-origin neuroendocrine neoplasms (NENs) and most appropriate treatment are scarce. Here, we report case patient who developed NEN confined LT was treated with re-transplantation (re-LT).A 49-year-old man no other medical co-morbidities underwent 2013 for alcoholic cirrhosis. donor...
Background: Hepatocellular carcinoma (HCC) is one of the leading indications for liver transplantation (LT) however, selection criteria remain controversial. We aimed to identify survival factors and predictors tumour recurrence using machine learning (ML) methods. also compared ML models Cox regression model. Methods: Thirty pretransplant donor recipient general specific parameters were analysed from 170 patients who underwent orthotopic HCC between March 2013 December 2019 at University...
Hepatocellular carcinoma is the fifth most common cancer in world and third leading cause of cancer-related death. It currently one indications for liver transplant, with selected 5-year survival rates after transplant about 70%. Despite excellent results hepatocellular carcinoma, a number patients develop metastases multifocal metastatic disease frequent In large autopsy series adrenal glands were site extrahepatic metastasis lungs bones. However, isolated rare, metachronous bilateral an...
Refractory ascites is a rare complication following orthotopic liver transplantation (OLT). The broad spectrum of differential diagnosis often leads to delay in diagnosis. Therapy depends on recognition and treatment the underlying cause. Constrictive pericarditis condition characterized by clinical signs right-sided heart failure. In advanced stages disease, hepatic congestion formation ascites. patients after OLT, cardiac etiology easily overlooked it requires high degree suspicion.We...
Acute kidney injury (AKI) after liver transplantation (LT) is a frequent and multifactorial event related to increased morbidity mortality. Risk factors for AKI LT still need be clarified.To identify the predictors of acute transplantation.The frequency pre- intraoperative within first 7 d were evaluated in adult transplant candidates single center Croatia. was defined according Kidney Disease: Improving Global Outcomes criteria.Out 205 patients (mean age 57 ± 10 years; 73.7% males, 52.7%...
The simultaneous occurrence of an abdominal aortic aneurysm and liver cirrhosis needing surgical treatment is extremely rare. There still controversy regarding the timing repair transplantation optimal aneurysm. Here, we describe a 70-year-old white male patient who presented with end-stage disease secondary to chronic hepatitis C solitary hepatocellular carcinoma measuring 5.5 cm in diameter right lobe. A pretransplant work-up resulted discovery 6.7-cm decision was made perform orthotopic...
¶ 12 41 M small intestine no 9 G2 octreotide 20 2019 2 (died) *performed on explanted liver tissue.†diagnosis defined after insight in tissue.‡insulinoma.§extirpation of primary tumor/extirpation recurrent tumor.IIliver + pancreas.¶after second transplantation.**retransplantation for hepatic artery thrombosis.† †primary tumor: donor lungs.‡ ‡year the transplantation.
Paraduodenal pancreatitis (PP) is a rare form of chronic presenting with symptoms duodenal obstruction. Conservative treatment often unsuccessful and pancreaticoduodenectomy the preferred surgical approach. A mini review outcomes therapy for PP shows that results are predominantly favorable.In our case report PP, we describe an unusual course first pseudocyst pancreatic tail. pseudocystojejunostomy was performed late postoperative complicated At laparotomy, found patient treated total...
To compare the long-term outcomes between liver transplant (LT) recipients with hepatocellular carcinoma (HCC) who were downstaged transarterial-chemoembolization (TACE) to Milan criteria (MC) and those initially meeting MC.This retrospective study enrolled 198 patients HCC: 38 160 met MC. Post-LT survival HCC recurrence-free evaluated. We assessed association of death recurrence TACE, baseline (age, sex, disease etiology, Model End-stage Liver Disease, tumor number sum maximum diameters,...