A5040190836- Multicomponent Synthesis of Heterocycles
- Synthesis and biological activity
- Quinazolinone synthesis and applications
- Synthesis and Biological Evaluation
- Chemical Synthesis and Analysis
- Analytical Chemistry and Chromatography
- Synthesis and Characterization of Heterocyclic Compounds
- Nanoparticles: synthesis and applications
- Bacterial Identification and Susceptibility Testing
- Catalytic C–H Functionalization Methods
- Macrophage Migration Inhibitory Factor
- Microwave-Assisted Synthesis and Applications
- Synthesis of β-Lactam Compounds
- Genomics, phytochemicals, and oxidative stress
- Computational Drug Discovery Methods
- Asymmetric Hydrogenation and Catalysis
- Synthesis and Catalytic Reactions
- Concrete and Cement Materials Research
- Bacterial biofilms and quorum sensing
- Chromatography in Natural Products
- Polydiacetylene-based materials and applications
- Magnesium Oxide Properties and Applications
- Epigenetics and DNA Methylation
- Advanced Theoretical and Applied Studies in Material Sciences and Geometry
- Antibiotic Resistance in Bacteria
Baku State University
2015-2024
Azerbaijan State Oil and Industry University
2021-2023
Known methods of synthesis dihydropyrimidines and their oxidized products were modified, the impact hydrogen bonds on stabilization preferred tautomer biological activities studied.
In the present study we had an aim to develop methods of functionalizing surface magnetite nanoparticles with cefotaxime and ceftriaxone antibiotics. The quantitative analysis nanostructured cephalosporins was determined by Atom Absorbance Spectroscopy (AAS) based on Lambert-Beer law. engineered nanostructures were tested gram-negative microorganisms Klebsiella spp., Enterobacteriaceae, gram-positive bacteria Staphylococcus aureus, each having multi-drug resistance properties.
The nanostructuring of hydroxyl-substituted diazacrown-ether (DC) by silver nanoparticles was obtained green synthesis method in order to increase the antibacterial activity nanoparticles. synthesized DC, nanoparticles, and nanosupramolecular complex (Ag@DC) were studied TEM, powder-XRD, NMR, IR, UV spectroscopy methods. Ag@DC nanostructures uniform their sizes ranged from 8 18 nm. IR spectra revealed noncovalent formation complex. activities prepared active agents investigated on...
Herein, we report the preparation of methyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2-dihydropyrimidine-5-carboxylate 2, obtained by regioselective oxidative dehydrogenation dihydropyrimidine derivative 1 in presence cerium ammonium nitrate. The structure compound 2 was investigated single-crystal X-ray diffraction (SC-XRD), which allowed determination its tautomeric form. Moreover, non-covalent interactions and their impact on crystal were analyzed. To better characterize intermolecular...
Scientists are increasingly using ruthenium catalysts to selectively add functional groups the C8 carbon of tetrahydroquinolines that versatile class heterocyclic compounds with diverse applications in chemistry. This article reviews recent advances ruthenium-catalyzed C8-functionalization reactions tetrahydroquinolines. We explore different approaches activate a controlled way. These include directed ortho-metalation, use coordination metal catalyst, and C-H activation methods. review...
This study is devoted to the synthesis of a 40-membered macroheterocycle with its further nanostructuring by magnetite nanoparticles. The mentioned was synthesized [2+2] cyclocondensation oxygen-containing diamine an aromatic dialdehyde in non-catalytic medium and no work-up procedure. structure obtained studied 1H 13C nuclear magnetic resonance spectroscopy matrix-assisted laser desorption/ionization-time flight mass spectrometry. Furthermore, nanosupramolecular complex macroheterocycles...
In the present paper synthesis and characterization of zeolite glass fiber supported zero valent iron nanoparticles (Ze-ZVI, GF-ZVI NPs) are reported.ZVI, Ze-ZVI NPs size, composition morphology were characterized by Scanning Electron Microscopy (SEM), Atomic Force (AFM), Energy Dispersive Spectroscopy (EDS). Synthesized nanostructures tested as reducing agents nitrate hexavalent Chromium. Batch experiments carried for revealing efficacy prepared nanomaterials (ZE-ZVI NPs). Nitrate removal...
This study is devoted to the synthesis of various ensembles on basis graphene oxide nanolayers and dihydropyrimidines investigation their antimicrobial activity. The “building blocks” ensembles, viz were synthesized by Biginelli reaction in presence low-toxic copper triflate under microwave conditions. positive side absence any additional purification stage, formed after cooling solution precipitate just washed with a few amount distilled water. structures compounds determined 1H, 13C...
We herein report the determination of cytotoxic activity and expression profiles some DNA repair genes newly synthesized azomethines in gastric cancer cell line (AGS). The studied novel compounds were by a condensation reaction received characterized 1H 13C NMR spectroscopy methods. Furthermore, they applied to AGS at eight different concentrations (0.1-50 µg/mL). Anticancer activities determined using MTT method. Expression levels ATR, ERCC1, TOP2A, ABCB1 RT-PCR Biochemical parameters also...
The synthesized S-enantiomer of the crown ether was used as an adsorbent to separate racemic mixture L-alanine phenamine into individual diastereomers by column chromatography. Chromatographic separation occurred due formation complexes different stability between and optically selective adsorbents on a host-guest principle. separated were converted enantiomers hydrolysis. structure optical activity investigated physicochemical methods