A5112096903- Reconstructive Surgery and Microvascular Techniques
- Breast Implant and Reconstruction
- Lymphatic System and Diseases
- Organ and Tissue Transplantation Research
- Wound Healing and Treatments
- Breast Cancer Treatment Studies
- Mesenchymal stem cell research
- Diagnosis and Treatment of Venous Diseases
- Vascular Procedures and Complications
- Digital Imaging in Medicine
- Reconstructive Facial Surgery Techniques
- Bone fractures and treatments
- Surgical Sutures and Adhesives
- Surgical site infection prevention
- Lymphatic Disorders and Treatments
- Oral health in cancer treatment
- Smoking Behavior and Cessation
- Nerve injury and regeneration
- Cardiac, Anesthesia and Surgical Outcomes
- Tracheal and airway disorders
- Head and Neck Cancer Studies
- Hospital Admissions and Outcomes
- Body Contouring and Surgery
- Nutrition and Health in Aging
- Diversity and Career in Medicine
The University of Texas MD Anderson Cancer Center
2021-2025
Creative Commons
2021-2023
University of Washington
2023
Washington University in St. Louis
2022-2023
Harvard University
2017-2023
Brigham and Women's Hospital
2019-2023
Harvard Affiliated Emergency Medicine Residency
2020-2021
Center For Reconstructive Urethral Surgery
2021
Hadassah Medical Center
2021
Massachusetts General Hospital
2017-2019
This study investigates the efficacy of local and intravenous mesenchymal stem cell (MSC) administration to augment neuroregeneration in both a sciatic nerve cut-and-repair rat hindlimb transplant model. Bone marrow-derived MSCs were harvested purified from Brown-Norway (BN) rats. Sciatic transections repairs performed three groups Lewis (LEW) rats: negative controls (n = 4), (epineural) injection systemic (intravenous) 4). Syngeneic (LEW-LEW) 4) allogeneic (BN-LEW) transplants assessed for...
Background: Tobacco use remains a persistent risk factor in elective plastic surgery. Although nicotine is thought to increase complications, which procedures are affected and the reliability of patient-provided histories remain poorly defined. The authors sought examine its impact on outcomes. Methods: All patients single-surgeon practice undergoing surgery with general anesthesia during 2-year period were enrolled. Preoperative evaluation included thorough smoking history. had urine...
OBJECT Total en bloc sacrectomy is a dramatic procedure that results in extensive sacral defects. The authors present series of patients who underwent flap reconstruction after total sacrectomy, report clinical outcomes, and provide treatment algorithm to guide surgical care this unique patient population. METHODS After institutional review board approval, data were collected for all between 2002 2012 at Johns Hopkins Hospital. Variables included demographic data, medical history, tumor...
Background: MRI-conditional tissue expanders (MRI-CTEs) were developed to address imaging artifacts and challenges in radiation planning associated with traditional (TTEs). This study aims compare the clinical outcomes protocol impacts of MRI-CTEs versus TTEs postmastectomy breast reconstruction. Methods: A retrospective review was conducted on immediate reconstruction or between 2021 2024. Outcomes such as seroma, infection, malposition, expander loss analyzed. Results: total 867 evaluated...
Osteoradionecrosis of the jaw (ORNJ) is a debilitating complication that affects up to 15% head and neck cancer patients who undergo radiotherapy. The ASCO/ISOO/MASCC-endorsed ClinRad severity classification system was recently proposed (and recommended in latest ASCO guidelines) incorporate radiographic findings for determining ORNJ based on vertical extent bone necrosis. However, variability imaging modalities specialty-specific knowledge may contribute disparities diagnosing classifying...
Reconstructing periorbital defects is challenging because of the simultaneous need for ocular support, corneal protection, and restoration aesthetic subtleties. In patients with extensive tissue loss, microvascular free transfer a reliable reconstructive option composite defects.The authors conducted retrospective review craniofacial identified those treated reconstruction at R Adams Cowley Shock Trauma Center The Johns Hopkins Hospital from 2001 to 2010.Twenty-four underwent flap secondary...
Background: Implicit gender bias may result in lower wages for women, fewer leadership positions, and perceived competence. Understanding public patient preferences plastic surgeons enable opportunities to address perceptions. This investigation evaluates a surgeon’s or demeanor. Methods: Members of the Amazon Mechanical Turk crowdsourcing platform read 1 8 randomly assigned scenarios describing hypothetical situation requiring surgeon operate on their mother. The differed only by gender,...
Background: The COVID-19 pandemic has significantly impacted residency application process for all specialties, including plastic surgery residency. Almost programs have suspended visiting sub-internship rotations. This study quantifies the impact of a webinar through an analysis poll questions and post-webinar survey sent to registered participants. Methods: A dedicated was organized held by Harvard Plastic Surgery Residency Training Program. All attendees were asked several during webinar....
Abstract Background Lower extremity free flap failure rates are higher than in other areas of the body. While prior studies assessed effect intraoperative technical variables, these generally investigated individual variables and did not examine relationships between many decisions made during tissue reconstruction. Our purpose was to investigate variation microsurgical techniques on outcomes a diverse cohort patients requiring lower coverage. Methods Consecutive undergoing reconstruction at...
Breast cancer treatment, including axillary lymph node excision, radiation, and chemotherapy, can cause upper extremity lymphedema, increasing morbidity health care costs. Institutions increasingly perform prophylactic lymphovenous bypass (LVB) at the time of dissection (ALND) to reduce risk lymphedema but reports complications are lacking. We examine records from American College Surgeons (ACS) National Surgery Quality Improvement Program (NSQIP) database safety these procedures. Procedures...
Background: In breast reconstruction, mastectomy and free flaps are susceptible to vascular compromise tissue necrosis. The SnapshotNIR device (Kent Imaging, Calgary, AB, Canada) utilizes near-infrared spectroscopy measure oxygen saturation (StO 2 ) hemoglobin concentration. Here, we report on the use of this for StO monitoring among patients receiving alloplastic or autologous reconstruction. Methods: Patients immediate reconstruction after were enrolled. Preoperative, intraoperative,...
Reconstructive transplantation such as extremity and face is a viable treatment option for select patients with devastating tissue loss. Sensorimotor recovery critical determinant of overall success transplants. Although motor function has been extensively studied, mechanisms sensory re-innervation are not well established. Recent clinical reports transplants confirm progressive improvement even in cases where optimal repair nerves was achieved. Two forms nerve regeneration known. In...
This study evaluates complications and reconstructive failure rates in implant-based reconstruction with radiotherapy.Postmastectomy radiotherapy may adversely affect breast outcomes. However, the comparative effect of on direct-to-implant versus tissue expander-implant has not been examined.Single institution retrospective review was performed patients were followed 2 to 10 years.Of 1566 patients, 265 received radiation (149 immediate implants 116 expanders). Demographics similar except...
Microsurgical free tissue transfer may be the only reconstructive option for lower extremity limb salvage. However, functional and aesthetic results following after initial salvage suboptimal, thus requiring secondary operations to facilitate definitive wound healing and/or refinement.A multi-institutional retrospective cohort study was performed including patients who underwent from January of 2002 December 2020. The authors' primary outcome variable presence surgery reconstruction....
ABSTRACT Background Adequate vascular anatomy and perfusion status are essential for successful lower extremity free tissue transfer. Computed tomography angiography (CTA) is widely available, minimally invasive, enables visualization of soft tissues bones. Angiography permits temporal evaluation flow, identifies potential needs concurrent endovascular interventions, enhances visibility in the setting hardware. Despite widespread availability these imaging modalities, no standardized...