- Reconstructive Surgery and Microvascular Techniques
- Nerve injury and regeneration
- Organ and Tissue Transplantation Research
- Nerve Injury and Rehabilitation
- Digital Imaging in Medicine
- Surgical Sutures and Adhesives
- Wound Healing and Treatments
- Breast Implant and Reconstruction
- Anatomy and Medical Technology
- Facial Rejuvenation and Surgery Techniques
- Transplantation: Methods and Outcomes
- Mesenchymal stem cell research
- Graphene and Nanomaterials Applications
- Botulinum Toxin and Related Neurological Disorders
- Burn Injury Management and Outcomes
- Surgical Simulation and Training
- Organ Donation and Transplantation
- Xenotransplantation and immune response
- Body Contouring and Surgery
- Head and Neck Surgical Oncology
- Organ Transplantation Techniques and Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Cerebral Palsy and Movement Disorders
- Reconstructive Facial Surgery Techniques
- Breast Cancer Treatment Studies
Johns Hopkins University
2013-2024
Creative Commons
2019-2023
Vanderbilt University Medical Center
2023
Royal Hospital
2023
Johns Hopkins Medicine
2012-2022
University of Toledo
2015-2021
University of Toledo Medical Center
2016-2017
Dellon Institutes for Peripheral Nerve Surgery
2016
Miami Hand Center
2016
American University of Beirut
2012-2014
This study investigates the efficacy of local and intravenous mesenchymal stem cell (MSC) administration to augment neuroregeneration in both a sciatic nerve cut-and-repair rat hindlimb transplant model. Bone marrow-derived MSCs were harvested purified from Brown-Norway (BN) rats. Sciatic transections repairs performed three groups Lewis (LEW) rats: negative controls (n = 4), (epineural) injection systemic (intravenous) 4). Syngeneic (LEW-LEW) 4) allogeneic (BN-LEW) transplants assessed for...
Background: Therapies to improve outcomes following peripheral nerve injury are lacking. Prolonged denervation of muscle and Schwann cells contributes poor outcomes. In this study, the authors assess effects growth hormone therapy on axonal regeneration, cell maintenance, end-organ reinnervation in rats. Methods: Male Sprague-Dawley rats underwent sciatic transection repair femoral without received either daily subcutaneous (0.4 mg/day) or no treatment ( n = 8 per group). At 5 weeks,...
One of the fundamental aspects initial burn care is ability to accurately measure TBSA injured tissue. Discrepancies between estimates size and actual (determined at unit) have long been reported. These inconsistencies potential for unnecessary patient transfer inappropriate fluid administration which may result in morbidity. In an effort study these their impact on care, we evaluated differences its resuscitation American Burn Association-verified pediatric center. A prospective...
Neoadjuvant chemotherapy (NC) is increasingly being used in patients with breast cancer, and evidence-based reports related to its independent effects on morbidity after mastectomy immediate reconstruction are limited.To determine the effect of NC 30-day postoperative women undergoing or without reconstruction.All from January 1, 2005, through December 31, 2011, at university private hospitals internationally were analyzed using American College Surgeons National Surgical Quality Improvement...
This article presents a small case series demonstrating clinical success with thrombolytic agents for severe frostbite injury to the lower extremities. The authors report three patients injuries their distal extremities who were managed urgent interventional radiology and intra-arterial tissue plasminogen activator infusion according prespecified protocol. Limbs digits successfully salvaged returned normal activity within 2 weeks. Although further studies are needed, results of this study...
Harvest of the rectus abdominis muscle requires an abdominal incision as well violation anterior sheath, creating potential for significant surgical-site morbidity (bulges, hernias, infections, seromas). Laparoscopic or endoscopic techniques, although feasible, have not become popular among plastic surgeons due to multiple technical shortcomings. Robotic surgery on other hand has easier learning curve, enhanced precision, tremor elimination, motion scaling, high resolution, three-dimensional...
Transoral robotic surgery (TORS) has emerged as a technique that allows head and neck surgeons to safely resect large complex oropharyngeal tumors without dividing the mandible or performing lip-split incision. These resections provide reconstructive challenge because cylinder of oropharynx remains closed both physical access visualization anatomy is severely restricted. reconstruction (TORRS) such defects surgeon inset free flaps perform adjacent tissue transfer while seeing what resecting...
Sir: Traumatic penile amputation is a rare but challenging injury that requires multidisciplinary approach. Because plastic surgeons are often called upon to take leading role in emergent microsurgical replantation, we can also find ourselves managing the resulting complications. Skin necrosis known be most common of these complications,1 there seems pervasive lack awareness regarding likely underlying cause. Authors tend assume culprit prolonged ischemic insult or swelling; however, clear...
Abdominal wall vascularized composite allotransplantation is the second most common form of allotransplantation. Sensory and functional recovery are expected in other forms but have never been demonstrated abdominal The authors hypothesize that coaptation two thoracolumbar nerves will result reinnervation alloflap maintenance muscle component.Adult, male, 10-week-old Brown Norway Lewis rats were used for experiments. rat donor's iliac vessels anastomosed to recipient's femoral vessels....
Background: Preoperative anemia is independently associated with adverse outcomes after general and cardiac surgery. Outcomes breast reconstruction are not established. We assessed the effect of preoperative on 30-day postoperative morbidity length hospital stay (LOS) in patients undergoing immediate reconstruction. Methods: identified from 2008 to 2010 American College Surgeons' National Surgical Quality Improvement Program database (a prospective outcomes-based registry hospitals...