A5046972463- Lung Cancer Treatments and Mutations
- Reconstructive Surgery and Microvascular Techniques
- Facial Trauma and Fracture Management
- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Colorectal and Anal Carcinomas
- Opioid Use Disorder Treatment
- Breast Cancer Treatment Studies
- Tryptophan and brain disorders
- Breast Implant and Reconstruction
- Head and Neck Cancer Studies
- Racial and Ethnic Identity Research
- Surgical Sutures and Adhesives
- Digital Imaging in Medicine
- PI3K/AKT/mTOR signaling in cancer
- Skin Protection and Aging
- Electroconvulsive Therapy Studies
- Healthcare Decision-Making and Restraints
- Cancer Genomics and Diagnostics
- Cutaneous Melanoma Detection and Management
- Stress Responses and Cortisol
- Attention Deficit Hyperactivity Disorder
- Maternal Mental Health During Pregnancy and Postpartum
- Cancer Diagnosis and Treatment
- Organ and Tissue Transplantation Research
Yale University
2018-2024
University of California, Los Angeles
2023-2024
University of Kentucky
2023
Centre for Advanced Process Technology for Urban Resource Recovery
2023
Stanford University
2021-2022
University School
2022
VA Connecticut Healthcare System
2020-2022
Yale New Haven Hospital
2022
VA Caribbean Healthcare System
2021
Johns Hopkins University
1958-2018
Continuing advances in cranioplasty have enabled repair of increasingly complicated cranial defects. However, the optimal materials and approaches for particular clinical scenarios remain unclear. This study examines outcomes following a variety indications patients treated with alloplastic material, autogenous tissue, or combination both.a retrospective analysis on 180 who had 195 cranioplasties performed between 1993 2010.Materials used included 42.6 percent (83 195), autologous 19.0 (37...
Objective: The aim of this case series was to assess the impact auditory rehabilitation with cochlear implantation on cognitive function elderly patients over time. Design: This is a longitudinal prospective data assessing neurocognitive and speech perception in an cohort pre- post-implantation. Setting: University implant center. Participants: were post-lingually deafened female (mean, 73.6 years; SD, 5.82; range, 67–81 years) recipients (n=7). Measurements: A battery 20 tests intellectual...
Adolescent depression is prevalent and associated with significant morbidity mortality. Although intravenous ketamine has shown efficacy in adult treatment-resistant depression, its pediatric populations unknown. The authors conducted an active-placebo-controlled study of ketamine's safety adolescents.In this proof-of-concept randomized, double-blind, single-dose crossover clinical trial, 17 adolescents (ages 13-17) a diagnosis major depressive disorder received single infusion either (0.5...
Objective: Adolescent depression is prevalent and associated with significant morbidity mortality. Although intravenous ketamine has shown efficacy in adult treatment-resistant depression, its pediatric populations unknown. The authors conducted an active-placebo-controlled study of ketamine's safety adolescents. Methods: In this proof-of-concept randomized, double-blind, single-dose crossover clinical trial, 17 adolescents (ages 13–17) a diagnosis major depressive disorder received single...
Chronic obstructive pulmonary disease (COPD) is underdiagnosed in primary care.
Neoadjuvant chemotherapy (NC) is increasingly being used in patients with breast cancer, and evidence-based reports related to its independent effects on morbidity after mastectomy immediate reconstruction are limited.To determine the effect of NC 30-day postoperative women undergoing or without reconstruction.All from January 1, 2005, through December 31, 2011, at university private hospitals internationally were analyzed using American College Surgeons National Surgical Quality Improvement...
The purpose of this study was to investigate whether a delay in operative management frontal sinus fractures is associated with increased risk serious infections.Retrospective chart review performed 242 consecutive patients surgically managed who presented the R Adams Cowley Shock Trauma Center between 1996 and 2011. Collected patient characteristics included demographics, surgical management, hospital course, complications. All computed tomographic imaging reviewed evaluate involvement...
Background: Multiple perfusion assessment technologies exist to identify compromised microvascular free flaps. The effectiveness, operability, and cost of each technology vary. authors investigated surgeon preference clinical behavior with several technologies. Methods: A questionnaire was sent members the American Society for Reconstructive Microsurgery concerning perceptions frequency use in varied situations. Demographic information also collected. Adjusted odds ratios were calculated...
Investigate whether adjuvant everolimus, an mTOR inhibitor, improves progression-free survival (PFS) in advanced-stage head and neck squamous cell carcinoma (HNSCC) provide outcomes related to correlative biological factors associated with disease control.This was a prospective, randomized, double-blind phase II trial of patients HNSCC from 13 institutions who were confirmed disease-free post-definitive therapy enrolled between December 2010 March 2015. Patients received everolimus or...
Purpose The aim of this article was to assess how regional facial fracture patterns predict mortality and occult intracranial injury after blunt trauma. Methods Retrospective chart review performed for blunt-mechanism craniofacial patients who presented an urban trauma center from 1998 2010. Fractures were confirmed by author computed tomographic imaging then grouped into 1 5 involvement representing all possible permutations facial-third injury. Mortality the presence injury, defined as...
Critically ill patients with COVID-19 infection on extracorporeal membrane oxygenation (ECMO) face high morbidity and mortality. Palliative care consultation may benefit these their families. Prior to the pandemic, our institution implemented a policy of automatic palliative for all ECMO due mortality, medical complexity, psychosocial distress associated cases.
Background: Preoperative anemia is independently associated with adverse outcomes after general and cardiac surgery. Outcomes breast reconstruction are not established. We assessed the effect of preoperative on 30-day postoperative morbidity length hospital stay (LOS) in patients undergoing immediate reconstruction. Methods: identified from 2008 to 2010 American College Surgeons' National Surgical Quality Improvement Program database (a prospective outcomes-based registry hospitals...
Members of racial and ethnic minority groups have been disproportionately impacted by coronavirus-2019 (COVID-19). The objective the study is to describe associations between race ethnicity on clinical outcomes such as need for mechanical ventilation mortality.
Background: Neoadjuvant radiotherapy (NRT) enhances breast-conserving surgery outcomes, reducing local recurrence of breast cancer and increasing median survival. However, its effect on postoperative morbidity remains under-studied. We sought to assess the impact NRT 30-day after mastectomy. Methods: analyzed data from women undergoing mastectomy (with or without immediate reconstruction) using American College Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) 2005–2011...