A5056267604- Reconstructive Surgery and Microvascular Techniques
- Organ and Tissue Transplantation Research
- Breast Implant and Reconstruction
- Lymphatic System and Diseases
- Digital Imaging in Medicine
- Biomedical Ethics and Regulation
- Diversity and Career in Medicine
- Surgical Sutures and Adhesives
- Anatomy and Medical Technology
- Surgical site infection prevention
- Reconstructive Facial Surgery Techniques
- Diagnosis and Treatment of Venous Diseases
- Wound Healing and Treatments
- Breast Cancer Treatment Studies
- Electrospun Nanofibers in Biomedical Applications
- Body Contouring and Surgery
- Sarcoma Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Hernia repair and management
- Vascular Procedures and Complications
- Tissue Engineering and Regenerative Medicine
- History of Medical Practice
- Pelvic and Acetabular Injuries
- Intensive Care Unit Cognitive Disorders
- Body Image and Dysmorphia Studies
Washington University in St. Louis
2020-2025
Johns Hopkins Hospital
2012-2024
University of Washington
2024
Creative Commons
2017-2023
Mayo Clinic in Florida
2023
WinnMed
2023
Harvard University
2022
Lancaster University
2022
University of California, Los Angeles
2021
Johns Hopkins Medicine
2011-2020
Background: As the rate of contralateral prophylactic mastectomy in breast cancer patients increases, more women are seeking immediate bilateral reconstruction. The authors evaluated complication rates index and breasts undergoing Methods: retrospectively reviewed outcomes all consecutive postmastectomy reconstruction for an combined with a between 2005 2010. Patient, tumor, reconstruction, outcome characteristics were compared same patient. Patients classified by method: implant, abdominal...
Summary: Although robotic surgery has been routinely established in other surgical disciplines, technologies have less readily adopted plastic surgery. Despite a strong demand for innovation and cutting-edge technology surgery, most reconstructive procedures, including microsurgery, continued to necessitate an open approach. Recent advances robotics artificial intelligence, however, are gaining momentum shown significant promise improve patient care These next-generation robots the potential...
Introduction Up to one-fifth of breast cancer survivors will develop chronic cancer-related lymphoedema (BCRL). To date, complex physical decongestion therapy (CDT) is the gold standard treatment. However, it mainly symptomatic and often ineffective in preventing BCRL progression. Lymphovenous anastomosis (LVA) vascularised lymph node transfer (VLNT) are microsurgical techniques that aim restore lymphatic drainage. This international randomised trial aims evaluate advantages interventions...
Mechanical stretch can activate long-lived changes in fibroblasts, increasing their contractility and initiating phenotypic transformations. This activation, critical to wound healing procedures such as skin grafting, increases with mechanical stimulus for cells cultured two-dimensional but is highly variable three-dimensional (3D) tissue. Here, we show that static of 3D tissues either increase or decrease fibroblast activation depending upon recursive cell–extracellular matrix (ECM)...
Background Nipple areola complex (NAC) reconstruction is the final stage in breast for many women. Although general population preferences on NAC aesthetics and sensation have been studied, it unclear if these align with of women who undergone mastectomy. Therefore, this study aimed to assess aesthetic sensory mastectomy inform subsequent neurotization. Methods We conducted a cross-sectional, Facebook-based, crowdsourcing campaign distribute survey (e.g., position, size, pigmentation)...
Background and Objectives Flashlamp pulsed-dye lasers (PDLs) revealed effective regression or arrest in patients with keloids our clinical studies [Kuo YR et al., Laser Surg Med 2004;34:104–108]. In this study, we further investigated whether the induction of keloid seen PDL treatment through activation mitogen-activated protein (MAP) kinase caspase promotes cell apoptosis reduces fibroblast proliferation. Study Design/Materials Methods Keloid tissues were obtained from 10 intralesional...
To assess outcomes of patients undergoing reconstruction after resection skull base tumors with the anterolateral thigh (ALT) free flap.Case series chart review.Thirty-four consecutive cancers involving that underwent ALT flap between 2005 and 2008 were reviewed.The was successfully used to reconstruct two, five, 17 anterior, lateral, posterior defects, respectively. In addition, six four combined anterior-lateral lateral-posterior respectively, reconstructed. The overall complication rate...
Background: Using the internal mammary vessels as recipient in free-flap autologous breast reconstruction has become a common practice. However, these are typically accessed by removing costochondral segment. The purpose of this study was to describe authors' rib-sparing technique for accessing that is efficient and reliable limits chest wall morbidity. Methods: authors analyzed 100 consecutive free-tissue transfers which were using technique. data obtained from prospectively maintained...
OBJECT Total en bloc sacrectomy is a dramatic procedure that results in extensive sacral defects. The authors present series of patients who underwent flap reconstruction after total sacrectomy, report clinical outcomes, and provide treatment algorithm to guide surgical care this unique patient population. METHODS After institutional review board approval, data were collected for all between 2002 2012 at Johns Hopkins Hospital. Variables included demographic data, medical history, tumor...
OBJECTIVE Resection of metastatic spine tumors can improve patients’ quality life by addressing pain or neurological compromise. However, resections are often complicated wound dehiscence, infection, instrumentation failures, and the need for reoperation. Moreover, when reoperations needed, most common indication is surgical site infection breakdown. In turn, increase morbidity as well length cost hospitalization. The aim this study was to examine perioperative risk factors associated with...
The presence within the cell of numerous organic phosphate compounds makes classical approach to study membrane permeability inadequate in case ion. Consequently, standard works on contain little reference this subject. use radioactive phosphorus it possible dynamics transfer across by adequate techniques. results such tracer experiments, even relatively simple systems, have shown that process is considerably more complex than monovalent cations or chloride.
Artificial intelligence (AI) has been a disruptive technology within health care, from the development of simple care algorithms to complex deep-learning models. AI potential reduce burden administrative tasks, advance clinical decision-making, and improve patient outcomes. Unlocking full requires analysis vast quantities information. Although holds tremendous promise, widespread adoption plastic surgery remains limited. Understanding basics is essential for surgeons evaluate uses AI. This...
The purpose of this report a small series was to describe the technique total sacrectomy reconstruction using pedicled vertical rectus abdominis musculocutaneous (VRAM) flow-through flap anastomosed free fibula flap.We reviewed all consecutive reconstructions performed from 2009 2011. Surgical and patient outcomes were assessed.Total included three two-stage three-stage VRAM patients which ambulated by discharge. Flap survival 100%. Pelvic ring defects reconstructed with A-frame struts...
Background: Composite tissue allograft transplantation is limited by risks of long-term immunosuppression. The authors investigated whether short-term immunosuppression combined with recipient immature dendritic cells pulsed donor antigens promotes composite survival. Methods: Orthotopic hind-limb transplants were performed (day 0) from Wistar-Furth (RT1u) to Lewis (RT1l) rats. Recipient propagated bone marrow granulocyte-macrophage colony-stimulating factor (bone marrow–derived cells) and...
Background: A possible complication of open, limited incision or endoscopic carpal tunnel release is transection the thenar branch median nerve superficial palmar arch. Knowledge anatomy these structures in relationship to transverse ligament critical preventing complications. The authors investigated anatomical relationships using cadaveric dissections. Methods: Forty-eight fresh cadaver hands were analyzed. distance between distal and arch, origin nerve, length measured. Results: In 48...
Soft-tissue reconstruction of the pelvis with vascularized tissue flaps has become an increasingly common procedure. The types and indications for their use vary, but all flap procedures are performed goal transferring from a donor site to recipient restore form function, obliterate dead space, create environment favorable wound healing. Oncologic surgeries, including total pelvic exenteration abdominoperineal resection, leading reconstruction. pedicle most commonly used following these...
Reconstruction of complex defects the anterior abdomen is both challenging and technically demanding for reconstructive surgeons. Advancements in use pedicle free tissue transfer along with bioprosthetic synthetic meshes have provided novel approaches to these defects. Accordingly, detailed knowledge abdominal wall lower extremity anatomy combination insight into design, implementation, limitations various flaps essential solve clinical problems. Although can be attributed a myriad etiologic...
Background: Multiple perfusion assessment technologies exist to identify compromised microvascular free flaps. The effectiveness, operability, and cost of each technology vary. authors investigated surgeon preference clinical behavior with several technologies. Methods: A questionnaire was sent members the American Society for Reconstructive Microsurgery concerning perceptions frequency use in varied situations. Demographic information also collected. Adjusted odds ratios were calculated...
Background: Innovation is an essential aspect of plastic and reconstructive surgery (PRS), whether it involves improving current processes or implementing radical change that disrupts the status quo. Collaborating sharing innovations help advance field PRS as a whole. Methods: An anonymous survey was administered to members American Association Plastic Surgeons on their opinions top five in last 100 years. Results: A list 69 unique were compiled; overall microsurgery, myocutaneous flaps,...
Sutureless anastomotic devices present several advantages over traditional suture anastomosis, including expanded global access to microvascular surgery, shorter operation and ischemic times, reduced costs. However, their adaptation for arterial use remains a challenge. This review aims provide comprehensive overview of sutureless approaches that are either FDA-approved or under investigation. These include extraluminal couplers, intraluminal devices, methods assisted by lasers vacuums, with...