A5009114182- Reconstructive Surgery and Microvascular Techniques
- Breast Implant and Reconstruction
- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Body Contouring and Surgery
- Lymphatic System and Diseases
- Breast Cancer Treatment Studies
- Cancer Diagnosis and Treatment
- Dermatologic Treatments and Research
- Organ and Tissue Transplantation Research
- Cancer Cells and Metastasis
- Reconstructive Facial Surgery Techniques
- Cell Adhesion Molecules Research
- Systemic Sclerosis and Related Diseases
- Angiogenesis and VEGF in Cancer
- Structural Analysis of Composite Materials
- Women's cancer prevention and management
- Public Relations and Crisis Communication
- Digital Imaging in Medicine
- Congenital limb and hand anomalies
- Chemokine receptors and signaling
- Pectus Deformity Diagnosis and Treatment
- Bone fractures and treatments
- Communication in Education and Healthcare
- Facial Nerve Paralysis Treatment and Research
Caritas-Krankenhaus St. Josef
2010-2025
University Hospital Regensburg
2006-2024
University of Regensburg
2005-2021
Caritas Hospital
2005
Many studies indicate that subclinical bacterial colonization plays a pivotal role in capsular contracture. Nevertheless, it has not been clarified whether stimuli are only associated with high-grade (Baker III/IV) or low-grade I/II) contractures. The study included 45 female patients suffering from unilateral fibrosis following augmentation mammaplasty silicone implants (smooth: n = 28; textured: 17). In total, there were 16 (35.6%) bacterially contaminated swabs. No significant difference...
Although thousands of breast cancer cells disseminate and home to bone marrow until primary surgery, usually less than a handful will succeed in establishing manifest metastases months years later. To identify signals that support survival or outgrowth patients, we profile rare marrow-derived disseminated (DCCs) long before manifestation metastasis IL6/PI3K-signaling as candidate pathway for DCC activation. Surprisingly, similar mammary epithelial cells, DCCs lack membranous IL6 receptor...
Introduction Up to one-fifth of breast cancer survivors will develop chronic cancer-related lymphoedema (BCRL). To date, complex physical decongestion therapy (CDT) is the gold standard treatment. However, it mainly symptomatic and often ineffective in preventing BCRL progression. Lymphovenous anastomosis (LVA) vascularised lymph node transfer (VLNT) are microsurgical techniques that aim restore lymphatic drainage. This international randomised trial aims evaluate advantages interventions...
BACKGROUND:Perioperatively, patients' hemodynamics are modulated predominantly by intravenous fluid administration and vasoactive pharmacological support. Vasopressor agents suspected to be detrimental on free flap survival the cause of vasoconstriction pedicle with consecutive reduce d overall perfusion aggravation dissection. OBJECTIVE:A novel, standardized restrictive perioperative hemodynamic management was assessed for its feasibility in clinical practice patients undergoing breast...
Abstract Purpose The aim of our study was to examine the surgical outcome and complications (efficiency) as well incidence locoregional recurrence distant metastases (oncological safety) in patients who underwent autologous fat grafting (AFG) breast following cancer surgery. Methods In monocentric cohort study, retrospective prospective data were collected from all consecutive AFG after between 2008 2020; a total 93 met inclusion criteria. Results Our long-term results showed no increase...
Background: Therapy for phantom sensation and limb pain following amputation is still difficult, because pathophysiologic mechanisms have not been clarified. This report illustrates a simple useful surgical intervention. The authors propose that changes at the peripheral nerve site can influence central feeling of pain. Methods: Fifteen patients (mean age, 56 years) with lower were included in study. In all patients, sciatic was split point approximately 3 cm proximal to popliteal fossa, two...
Introduction: Autologous fat transfer has recently become an increasingly popular surgical procedure and comprises harvesting, processing transplantation of adipose tissue, as well professional follow-up care. This method, a procedure, can be utilised for trauma-, disease- or age-related soft tissue volume deficits augmentation. As usage is increasing, but the variables harvest, specific indications fashion are poorly defined, there great demand development guideline in field reconstructive...
The use of systemic prophylactic antibiotics to reduce surgical-site infection in esthetic breast surgery remains controversial, although the majority surgeons prefer utilize prevent infection. Nonetheless, postoperative acute and subclinical capsular fibrosis are among most common complications following implant-based reconstruction. After augmentation, up 2.9% women develop infection, with an incidence rate 1.7% for infections 0.8% late infections. postmastectomy reconstruction (secondary...
Grafting of autologous lipoaspirate for various clinical applications has become a common procedure in practice. With an estimated mortality rate 10-15 percent, fat embolism is among the most severe complications to be expected after lipofilling therapies.The aim this study was determine level interstitial pressure injection defined volumes into subcutaneous tissue female breasts. It hypothesized, that levels exceed physiologic capillary during procedures and hence increase potential risk...
Breast Carcinoma is the most common malign tumor disease in women. 20-30% of these tumors have to be treated by removing all breast tissue. After that kind therapeutic procedure, women are severely traumatized and ask for reconstruction. The goldstandard reconstruction free perforator flap from lower abdomen (DIEAP-flap), which can provide body-own tissue natural shape reconstructed breast.Many studies evaluate but neglect skin sensitivity. Claim this study was compare important part on two...
Abstract Purpose Lipofilling has been established as a standard technique for contour enhancement following breast reconstruction. However, there is paucity in current literature regarding the use of this complete reconstruction female an alternative to conventional techniques, such expander or flap-based procedures. In particular, influence pre-operative irradiation successful rarely examined published studies. Here, authors describe their experience with fat injection pre-radiated breasts...
Neben den etablierten Techniken der gestielten und freien Gewebetransplantation zur Brustrekonstruktion werden als regenerative Therapieansätze das "Adipose Tissue Engineering" die autologe Fettgewebstransplantation "Structural Fat Grafting" verfolgt. Während Anfangseuphorie des Adipose Engineering in absehbarer Zeit erfolgreich Zell-Matrixkonstrukte ausreichender Größe, Funktionalität langfristiger Volumenstabilität beim Menschen einzusetzen etwas geschwunden ist, erfährt Grafting seit...
BACKGROUND:A physiological and minimal invasive form of surgery with risk to treat lymphedemas is the so-called supermicrosurgical lymphovenous anastomosis (LVA) where a lymph vessel connected venule. METHODS:30 patients (between 2018 2019) secondary upper extremity edema refractory conservative therapy (manual drainage compression were operated using "simplified anastomosis" method). For assessment lymphatic supermicrosurgery, an operating microscope in which near-infrared illumination...
Extracorporeal shock wave therapy has undergone continuous development and become a well-established option both in urology orthopaedics/trauma surgery. Experimental clinical studies have proved the effectiveness of extracorporeal treatment connective tissue diseases such as fibromatosis.
ABSTRACT Introduction Up to one fifth of breast cancer survivors will develop chronic cancer-related lymphedema (BCRL). To date complex physical decongestion therapy (CDT) is the gold standard treatment. However, it mainly symptomatic and often ineffective in preventing BCRL progression. Lymphovenous anastomosis (LVA) vascularized lymph node transfer (VLNT) are microsurgical techniques that aim restore lymphatic drainage. This international randomized trial aims evaluate advantages...
Since the first use of silicone implants by Cronin in 1962, there have been several attempts to introduce alternative filling materials for breast on market. A promising new development are lightweight implants, whose filler material is one third lighter than conventional gel. While these used primarily aesthetic augmentation, a benefit could be expected particularly post-mastectomy reconstruction.Since 2019, 92 operations using performed at our clinic, 61 them reconstruction after...
The demand for prophylactic mastectomy has increased significantly over the last 10 years. This can be explained by a substantial gain of knowledge about clinical risk and outcome patients with high mutations such as BRCA1 2, improved diagnostic possibilities detecting genetic predisposition development breast cancer awareness those health care professionals well patients. In addition to expander-to-implant reconstruction microsurgical flap surgery, definitive immediate subpectoral insertion...
Autologous fat grafting (AFG) has been established over the past two decades as an additive technique during and after breast reconstruction. Complete reconstruction of mound with AFG alone represents exceptional that published mostly in case reports or studies limited cases.The purpose this study is to investigate influence three different techniques for on recovery skin sensitivity at reconstructed breast.The included 30 patients mastectomy following cancer. Three groups were examined: A)...
Reconstructive surgery is established as a standard treatment option after mastectomy due to cancer. It crucial patients achieve natural and symmetric looking breast through reconstruction. Anthropometric measurements are used assess the objective symmetry of breast, which prone errors difficult reproduce.The aim this work validate volumetry using three-dimensional surface imaging.We compared preoperatively analog digitally evaluated volume with our gold standard, direct water displacement...