A5069288624- Reconstructive Surgery and Microvascular Techniques
- Breast Implant and Reconstruction
- Mesenchymal stem cell research
- Reconstructive Facial Surgery Techniques
- Wound Healing and Treatments
- Body Contouring and Surgery
- Orthopedic Surgery and Rehabilitation
- Lymphatic System and Diseases
- Tissue Engineering and Regenerative Medicine
- Facial Nerve Paralysis Treatment and Research
- Bone fractures and treatments
- Surgical site infection prevention
- Breast Cancer Treatment Studies
- Anatomy and Medical Technology
- Facial Rejuvenation and Surgery Techniques
- Digital Imaging in Medicine
- Periodontal Regeneration and Treatments
- Dermatologic Treatments and Research
- Surgical Sutures and Adhesives
- Organ and Tissue Transplantation Research
- Diabetic Foot Ulcer Assessment and Management
- Diagnosis and Treatment of Venous Diseases
- Transplantation: Methods and Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Cancer Cells and Metastasis
University Hospital Regensburg
2016-2025
University of Regensburg
2014-2024
Tirol Kliniken
2024
University Hospital Innsbruck
2021-2024
Kepler Universitätsklinikum
2024
Caritas-Krankenhaus St. Josef
2009-2023
Caritas Hospital
2005-2023
München Klinik Bogenhausen
2022
The University of Texas MD Anderson Cancer Center
2010-2022
University of Medicine Mandalay
2022
This study investigates the accuracy of deep learning models for inference Reynolds-averaged Navier–Stokes (RANS) solutions. focuses on a modernized U-net architecture and evaluates large number trained neural networks with respect to their calculation pressure velocity distributions. In particular, it is illustrated how training data size weights influence With best models, this arrives at mean relative error less than 3% across range previously unseen airfoil shapes. addition all source...
Murine regulatory T (Treg) cells in tissues promote tissue homeostasis and regeneration. We sought to identify features that characterize human Treg with these functions healthy tissues. Single-cell chromatin accessibility profiles of murine defined a conserved, microbiota-independent tissue-repair signature prevailing footprint the transcription factor BATF. This signature, combined gene expression profiling TCR fate mapping, identified population tissue-like peripheral blood expressed...
Background The United States Medical Licensing Examination (USMLE) has been critical in medical education since 1992, testing various aspects of a student’s knowledge and skills through different steps, based on their training level. Artificial intelligence (AI) tools, including chatbots like ChatGPT, are emerging technologies with potential applications medicine. However, comprehensive studies analyzing ChatGPT’s performance USMLE Step 3 large-scale scenarios comparing versions ChatGPT...
Induction of chondrogenesis in mesenchymal stem cells (MSCs) with TGF-β leads to a hypertrophic phenotype. The maturation the chondrocytes is dependent on timed removal and sensitive hypertrophy-promoting agents vitro. In this study, we have investigated whether TGF-β3, which has been shown be more prochondrogenic compared TGF-β1, similarly enhances terminal differentiation an vitro hypertrophy model chondrogenically differentiating MSCs. addition, tested impact time chondrogenic...
A study was performed to investigate histological changes in capsules formed around silicone breast implants and their correlation with the clinical classification of capsular contracture defined by Baker score. For classification, authors used introduced Wilflingseder, which identifies four grades contracture.The included 24 female patients (average age, 40 +/- 12 years) after bilateral cosmetic augmentation smooth gel (Mentor, Santa Barbara, Calif.). The score determined preoperatively for...
Tissue engineering is a promising approach for the treatment of tissue defects. Mesenchymal stem cells are potential use as source repair or important growth factors engineering. The purpose this study was to examine role mesenchymal in meniscal repair. This tested using several cell and biomaterial-based options defects avascular zone rabbit menisci. Circular punch (2 mm) were created menisci left empty filled with hyaluronan-collagen composite matrices without cells, loaded platelet-rich...
Abstract BACKGROUND Recent evidence indicates that cancer stem cells play an important role in tumor initiation and maintenance. Additionally, the effect of tissue‐resident located surrounding healthy tissue on progression has been demonstrated. While most knowledge derived from studies breast cells, little is known regarding influence resident biology prostate cancer. METHODS Twenty male athymic Swiss nu/nu mice (age: 6–8 weeks) were randomized into two treatment groups: (1) subcutaneous...
Wound repair is a quiescent mechanism to restore barriers in multicellular organisms upon injury. In chronic wounds, however, this program prematurely stalls. It known that patterns of extracellular signals within the wound fluid are crucial healing. Extracellular pH (pHe) precisely regulated and potentially important signaling wounds due its diverse cellular effects. Additionally, sufficient oxygenation prerequisite for cell proliferation protein synthesis during tissue repair. was,...
Meniscal tears in the avascular zone have a poor self-healing potential, however partial meniscectomy predisposes knee for early osteoarthritis. Tissue engineering with mesenchymal stem cells and hyaluronan collagen based scaffold is promising approach to repair meniscal zone. 4 mm longitudinal of lateral menisci New Zealand White Rabbits were performed. The defect was left empty, sutured 5–0 suture or filled hyaluronan/collagen composite matrix without cells, platelet rich plasma autologous...
Lymphatic malformations (LM) are characterized by the overgrowth of lymphatic vessels during pre- and postnatal development. Macrocystic, microcystic combined forms LM known. The cysts lined endothelial cells (LECs). Resection sclerotherapy most common treatment methods. Recent studies performed on specimens in United States America have identified activating mutations phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) gene LM. However, whole tissue but not...
CD8 T lymphocytes are classically viewed as cytotoxic cells. Whether human cells can, in parallel, induce a tissue regeneration program is poorly understood. Here, antigen-specific assay systems revealed that not only mediated cytotoxicity but also promoted remodeling. Activated could produce the epidermal growth factor receptor (EGFR)-ligand amphiregulin (AREG) and sensitize epithelial for enhanced potential. Blocking EGFR or effector cytokines IFN-γ TNF inhibit This regenerative tumor...
Modern tattoo colourants frequently consist of azo pigments that not only contain multiple impurities but also are originally produced for car paint and the dyeing consumer goods.In order to be able assess health risk tattoos, it is important determine pigment concentration in human skin.We tattooed excised pigskin skin with a common (Pigment Red 22) under various conditions. After tattooing, we quantitatively extracted skin.The ranged from about 0.60 9.42 mg/cm(2) (mean value 2.53 mg/cm(2))...
Objective: A prospective, randomized, bicentric, nonblinded, clinical study was conducted to evaluate the impact on wound healing of Suprathel in partial-thickness burn injuries. represents an absorbable, synthetic dressing with properties natural epithelium. Methods: Thirty patients suffering from second-degree injuries were included study, a mean age 40.4 years old. Burn randomly selected, partly treated Omiderm and Suprathel. The first gauze change applied fifth day postoperatively,...
Abstract ChatGPT has garnered attention as a multifaceted AI chatbot with potential applications in medicine. Despite intriguing preliminary findings areas such clinical management and patient education, there remains substantial knowledge gap comprehensively understanding the chances limitations of ChatGPT’s capabilities, especially medical test-taking education. A total n = 2,729 USMLE Step 1 practice questions were extracted from Amboss question bank. After excluding 352 image-based...
Abstract Background Midfacial aging involves skeletal changes, muscle weakening, and fat redistribution, resulting in volume loss, skin sagging, deepened nasolabial folds. High-Intensity Facial Electrical Stimulation (HIFES) combined with Radiofrequency (RF) is a novel non-invasive method to address these changes by enhancing mass remodeling subcutaneous tissue. Objectives To assess the efficacy of HIFES Synchronized RF improving midfacial aesthetics, specifically thickness, displacement,...
Abstract Purpose This study aimed to clarify the applicability of smartphone-based three-dimensional (3D) surface imaging for clinical use in oral and maxillofacial surgery, comparing two approaches gold standard. Methods Facial models (SMs) were generated 30 volunteers (15 men, 15 women) using Vectra M5 ( Canfield Scientific, USA ), TrueDepth camera iPhone 14 Pro Apple Inc., with photogrammetry. Smartphone-based SMs superimposed onto Vectra-based SMs. Linear measurements volumetric...