A5025299975- Breast Implant and Reconstruction
- Reconstructive Surgery and Microvascular Techniques
- Breast Cancer Treatment Studies
- Osteoarthritis Treatment and Mechanisms
- Reconstructive Facial Surgery Techniques
- Body Contouring and Surgery
- Nasal Surgery and Airway Studies
- Body Image and Dysmorphia Studies
- Facial Rejuvenation and Surgery Techniques
- Knee injuries and reconstruction techniques
- Lymphatic System and Diseases
- Infant Nutrition and Health
- Mesenchymal stem cell research
- Digital Imaging in Medicine
- Dermatologic Treatments and Research
- Periodontal Regeneration and Treatments
- Breast Lesions and Carcinomas
- Nonmelanoma Skin Cancer Studies
- Breastfeeding Practices and Influences
- Fatty Acid Research and Health
- Bone fractures and treatments
- Orthopedic Surgery and Rehabilitation
- Diabetic Foot Ulcer Assessment and Management
- Facial Nerve Paralysis Treatment and Research
- Sarcoma Diagnosis and Treatment
University of Basel
2016-2025
University Hospital of Basel
2016-2025
Breast Center
2017-2024
Turku University Hospital
2020
University of Turku
2020
University of Lausanne
2018-2020
Zero to Three
2017-2018
Creative Commons
2017
Ospedale regionale di Lugano
2016-2017
Ente Ospedaliero Cantonale
2016-2017
Positive effects on mood have been observed in subjects who underwent treatment of glabellar frown lines with botulinum toxin and, an open case series, depression remitted or improved after such treatment. Using a randomized double-blind placebo-controlled trial design we assessed injection to the region as adjunctive major depression. Thirty patients were randomly assigned verum (onabotulinumtoxinA, n = 15) placebo (saline, group. The primary end point was change 17-item version Hamilton...
Abstract Background It has been hypothesized that bacterial biofilms on breast implants may cause chronic inflammation leading to capsular contracture. The association between of removed and contracture was investigated. Methods Breast explanted 2006 2010 at five participating centres for plastic reconstructive surgery were investigated by sonication. Bacterial cultures derived from sonication correlated with patient, surgical implant characteristics, the degree Results study included 121 84...
Milk samples were collected from 10 mothers by a standardised technique with complete expression of both breasts at each feed for 24 hours. Samples obtained 8 intervals during the first 36 days lactation. Analyses performed trichloroacetic acid-precipitable protein, total lactose, triglycerides, phospholipids, cholesterol, energy, sodium, potassium, calcium, magnesium, zinc, copper, pH, and osmolality. The results give comprehensive picture development milk composition transitional to mature...
Demand for nipple- and skin- sparing mastectomy (NSM/SSM) with immediate breast reconstruction (BR) has increased at the same time as indications post-mastectomy radiation therapy (PMRT) have broadened. The aim of Oncoplastic Breast Consortium initiative was to address relevant questions arising this clinically challenging scenario.A large global panel oncologic, oncoplastic reconstructive surgeons, patient advocates oncologists developed recommendations clinical practice in an iterative...
Abstract Stromal Vascular Fraction (SVF) cells freshly isolated from adipose tissue include osteogenic- and vascular-progenitors, yet their relevance in bone fracture healing is currently unknown. Here, we investigated whether human SVF directly contribute to the repair of experimental fractures nude rats, explored feasibility/safety clinical use for augmentation upper arm elderly individuals. Human were loaded onto ceramic granules within fibrin gel implanted critical rat femoral after...
In aesthetic clinical practice, surgical outcome is best measured by patient satisfaction and quality of life. For many years, there has been a lack validated questionnaires. Recently, the FACE-Q was introduced, authors present largest series face-lift patients evaluated with longest follow-up to date.Two hundred consecutive were identified who underwent high-superficial musculoaponeurotic system face lifts, or without additional facial rejuvenation procedures, between January 2005 2015....
Introduction Up to one-fifth of breast cancer survivors will develop chronic cancer-related lymphoedema (BCRL). To date, complex physical decongestion therapy (CDT) is the gold standard treatment. However, it mainly symptomatic and often ineffective in preventing BCRL progression. Lymphovenous anastomosis (LVA) vascularised lymph node transfer (VLNT) are microsurgical techniques that aim restore lymphatic drainage. This international randomised trial aims evaluate advantages interventions...
Cartilage lesions do not heal spontaneously and predispose to osteoarthritis. Functional cartilage tissues, engineered using autologous chondrocytes, have a therapeutic advantage over conventional cellular therapies in preclinical studies. Here, we tested whether ex vivo maturation of grafts for repair leads improved patient benefit. Using nasal chondrocytes (NCs), implantation vitro-matured NC-tissue-engineered (N-TEC) versus undifferentiated NC-cell-activated matrices (N-CAM) focal would...
Osteoarthritis (OA) is the most prevalent joint disorder, causing pain and disability predominantly in aging population but also affecting young individuals. Current treatments are limited to use of anti-inflammatory drugs alleviate symptoms or degenerated replacement by a prosthetic implant at end stage disease. We hypothesized that degenerative cartilage defects can be treated using nasal chondrocyte–based tissue-engineered (N-TEC). demonstrate N-TEC maintained cartilaginous properties...
The emphasis on aesthetic outcomes and quality of life (QoL) has motivated surgeons to develop skin-sparing or nipple-sparing mastectomy (SSM/ NSM) for breast cancer treatment prevention. During the same operation, a so-called immediate reconstruction is performed. can be reconstructed by positioning implant above (prepectoral) below (subpectoral) pectoralis major muscle using patients' own tissue (autologous reconstruction). optimal prepectoral subpectoral currently not clear. Subpectoral...
In Brief Objective: To investigate if precultivation of human engineered nasal cartilage grafts clinically relevant size would increase the suture retention strength at implantation and tensile bending stiffness 2 weeks after implantation. Summary Background Information: be used for reconstruction defects, need to reliably sutured resist bending/tension forces about surgery, when fixation is typically removed. Methods: Nasal septum chondrocytes from 4 donors were expanded passages statically...