A5079760420- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Lower Extremity Biomechanics and Pathologies
- Trauma Management and Diagnosis
- Total Knee Arthroplasty Outcomes
- Knee injuries and reconstruction techniques
- Osteoarthritis Treatment and Mechanisms
- Sports injuries and prevention
- Foot and Ankle Surgery
- Tendon Structure and Treatment
- Bone fractures and treatments
- Spine and Intervertebral Disc Pathology
- Orthopedic Surgery and Rehabilitation
- Orthopedic Infections and Treatments
- Nerve Injury and Rehabilitation
- Spinal Fractures and Fixation Techniques
- Elbow and Forearm Trauma Treatment
- Hip disorders and treatments
- Diabetic Foot Ulcer Assessment and Management
- Pelvic and Acetabular Injuries
- Musculoskeletal synovial abnormalities and treatments
- Artificial Intelligence in Healthcare and Education
- Surgical site infection prevention
- Orthopaedic implants and arthroplasty
- Muscle activation and electromyography studies
University Medical Center Freiburg
2016-2025
University of Freiburg
2016-2025
Fraunhofer Institute for Digital Medicine
2018
Fasa University of Medical Sciences
2014
Charité - Universitätsmedizin Berlin
2005-2014
MS-Schramberg (Germany)
2009
To define prognostic factors in chronically symptomatic patients with calcific tendinitis of the shoulder.We evaluated 420 (488 shoulders) context a prospective cohort study. Epidemiologic data were assessed. The radiographic and sonographic appearance deposits was classified. mean period nonoperative therapy 4.4 years (range 0.5-13.7 years). After referral to our institution, standardized continued for minimum 3 months. Failure defined as persistence shoulder after 6 Prognostic (determined...
Objective To evaluate the clinical outcome of a hydrogel-based autologous chondrocyte implantation (ACI) for large articular cartilage defects in knee joint. Design Prospective, multicenter, single-arm, phase III trial. ACI was performed 100 patients with focal full-thickness ranging from 4 to 12 cm 2 size. The primary measure responder rate at years using Knee Injury and Osteoarthritis Outcome Score (KOOS). Results Two after treatment, 93% were KOOS responders having improved by ≥10 points...
Abstract Introduction Implantation of minced cartilage is a one-step-procedure that leads to satisfactory results in osteochondral defects. Material and methods A retrospective review was performed on consecutive cohort patients received with fibrin (MCF), membrane (MCMF) the “AutoCart”-procedure (MCAC) between January 2019 December 2023. Radiological outcome parameters were evaluated via Magnet-Resonance-Tomography (MRI) within one year using Ankle-Osteoarthritis-Scoring-System (AOSS)....
Cartilage lesions do not heal spontaneously and predispose to osteoarthritis. Functional cartilage tissues, engineered using autologous chondrocytes, have a therapeutic advantage over conventional cellular therapies in preclinical studies. Here, we tested whether ex vivo maturation of grafts for repair leads improved patient benefit. Using nasal chondrocytes (NCs), implantation vitro-matured NC-tissue-engineered (N-TEC) versus undifferentiated NC-cell-activated matrices (N-CAM) focal would...
Abstract Purpose Anterior knee pain is a frequent symptom caused by disorders like patellofemoral syndrome or patella tendon tendinitis, which commonly treated conservatively. The aim of the current study was to examine effectiveness digital therapeutic (DT) versus German standard care through prospective, randomized, multicenter controlled trial. Methods Study participants were recruited in 9 orthopedic specialist centers diagnosed with anterior and NPRS score ≥ 4. Stratified randomization...
Background: Rupture of the ACL is a common injury among men and women athletes. While planning surgical reconstruction procedure, eventual graft’s diameter extremely important. Many parameters are therefore evaluated pre-surgery to ensure access reliable data for estimating graft diameter. Considering this, magnetic resonance imaging (MRI), particularly qualitative analyses hamstring tendons, offers promising approach. Methods: In retrospective analysis, we carried out 3D segmentation...
In Brief Study Design. Comparison of the dose area product (DAP), radiation time and operation during computer navigated conventional balloon kyphoplasty procedures. Objective. To compare patients exposure in a procedure with without using navigation system for placement working needles. Summary Background Data. Minimal invasive spine surgery is associated high both patient surgeon. The use has led to reduced experimental trials. our knowledge, there no clinical data determining influence on...
Reconstruction of the medial patellofemoral ligament (MPFL) has become a popular surgical procedure to address instability. As consequence growing number MPFL reconstructions performed, higher rate failures and revision procedures been seen.To perform failure analysis in patients with patellar redislocation after primary isolated reconstruction.Case series; Level evidence, 4.Patients undergoing surgery for reinstability reconstruction were included. Clinical notes reviewed collect...
The purpose of this study was to evaluate the perspective orthopaedic surgeons on impact artificial intelligence (AI) and influence experience, workplace setting familiarity with digital solutions views AI.
Discogenic low back pain (LBP) is a main cause of disability and inflammation presumed to be major driver symptomatic intervertebral disc degeneration (IDD). Anti-inflammatory agents are currently under investigation as they demonstrated alleviate symptoms in patients having IDD. However, their underlying anti-inflammatory regenerative activity poorly explored. The present study sought investigate the potential Etanercept Tofacitinib for maintaining homeostasis preclinical (IVD) organ...
Failure of isolated primary meniscal repair must be expected in approximately 10-25% cases. Patients requiring revision surgery may benefit from repair, however, the results this procedure remain underreported. The purpose study was therefore to evaluate outcome and failure rates patients with re-tears or failed healing after previous stable knee joints.A chart review performed identify all undergoing between 08/2010 02/2016. Only without concomitant procedures, ligamentous insufficiency, a...
Horizontal instability impairs clinical outcome following acute acromioclavicular joint (ACJ) reconstruction and may be caused by insufficient healing of the superior ligament complex (ACLC). However, characteristics ACLC injuries are poorly understood so far. Purposes this study were to identify different tear types, assess type-specific prevalence determine influencing cofactors. This prospective, cross-sectional comprised 65 patients with acute-traumatic Rockwood-5 (n = 57) Rockwood-4 8)...
Although minimally invasive posterior spine implant systems have been introduced, clinical studies reported on reduced quality of spinal column realignment due to correction loss. The aim this study was compare biomechanically two stabilization versus the Universal Spine Stabilization system (USS). Three groups with 5 specimens each and 2 foam bars per specimen were instrumented USS (Group 1) or a either polyaxial 2) monoaxial 3) screws. Mechanical testing performed under quasi-static ramp...
Background: Matrix-associated autologous chondrocyte implantation (ACI) is a well-established treatment for cartilage defects. High-level evidence at midterm follow-up limited, especially ACI using spheroids (spherical aggregates of ex vivo expanded human chondrocytes and self-synthesized extracellular matrix). Purpose: To assess the safety efficacy 3-dimensional matrix-associated to treat medium large defects on different locations in knee joint (patella, trochlea, femoral condyle) 5-year...
An arthroscopically assisted technique for the treatment of acute acromioclavicular joint dislocations is presented. This pathology-based procedure aims to achieve anatomic healing both ligament complex (ACLC) and coracoclavicular ligaments. First, reduced anatomically under macroscopic radiologic control temporarily transfixed with a K-wire. A single-channel using 2 suture tapes provides secure stabilization. The key step consists repair ACLC ("AC-Reco"). Basically, we have observed 4...
Purpose To demonstrate improved T 2 and 1ρ mapping of patellofemoral cartilage with in situ loading by means prospective motion correction to assess load‐induced changes healthy subjects. Materials Methods Established sequences were augmented based on optical tracking. Protocols optimized for robust imaging the at a field strength 3T. Subjects positioned scanner knee flexion joint was performed pneumatic device. In pilot study cohort 10 subjects, evaluated through measurements axial loads...