- Bone health and treatments
- Liver Disease Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Bone health and osteoporosis research
- Lipid metabolism and biosynthesis
- Total Knee Arthroplasty Outcomes
- Metabolism, Diabetes, and Cancer
- Effects and risks of endocrine disrupting chemicals
- Bone and Joint Diseases
- Tracheal and airway disorders
- Adipose Tissue and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- Radiopharmaceutical Chemistry and Applications
- Estrogen and related hormone effects
- MRI in cancer diagnosis
- Platelet Disorders and Treatments
- Otitis Media and Relapsing Polychondritis
- Knee injuries and reconstruction techniques
- Lower Extremity Biomechanics and Pathologies
- Nuclear Structure and Function
- Bone Metabolism and Diseases
- Advanced MRI Techniques and Applications
University of Freiburg
2024-2025
University Medical Center Hamburg-Eppendorf
2014-2018
Universität Hamburg
2014-2018
Ege University
2012-2014
Skeletal health relies on architectural integrity and sufficient bone mass, which are maintained through a tightly regulated equilibrium of resorption by osteoclasts formation osteoblasts. Genetic studies have linked the gene coding for low-density lipoprotein receptor-related protein1 (Lrp1) to traits but whether these associations based causal molecular relationship is unknown. Here, we show that Lrp1 in osteoblasts novel regulator osteoclast activity mass. Mice lacking specifically...
Cartilage lesions do not heal spontaneously and predispose to osteoarthritis. Functional cartilage tissues, engineered using autologous chondrocytes, have a therapeutic advantage over conventional cellular therapies in preclinical studies. Here, we tested whether ex vivo maturation of grafts for repair leads improved patient benefit. Using nasal chondrocytes (NCs), implantation vitro-matured NC-tissue-engineered (N-TEC) versus undifferentiated NC-cell-activated matrices (N-CAM) focal would...
Recent studies revealed that inflammation plays a critical role in bone remodeling and the pathogenesis of postmenopausal osteoporosis, major health concern. Neutrophil-lymphocyte ratio (NLR) is cost-effective marker has been linked with several diseases. This study aimed to compare NLR C-reactive protein (CRP) levels osteopenic, osteoporotic, control subjects assess correlation between levels, CRP, mineral density (BMD) women.In this cross-sectional study, relationship NLR, BMD 438 women...
Abstract Purpose Different cartilage repair techniques are widely used to regenerate cartilage, such as autologous chondrocyte implantation (ACI), osteochondral autograft transfer, microfracturing and minced cartilage. Defect size is a key parameter for selecting the best procedure However, defect's not related patient's total surface. This because assessing femoral surface area time‐consuming therefore unsuitable in daily clinical routine. It has been proposed that femur's correlates...
Searchable abstracts of presentations at key conferences on calcified tissues ISSN 2052-1219 (online)