A5019532909- Advanced MRI Techniques and Applications
- Medical Image Segmentation Techniques
- Lower Extremity Biomechanics and Pathologies
- Sarcoma Diagnosis and Treatment
- Foot and Ankle Surgery
- Advanced Neuroimaging Techniques and Applications
- Surgical Simulation and Training
- Bone Tumor Diagnosis and Treatments
- Bone fractures and treatments
- Functional Brain Connectivity Studies
- Tendon Structure and Treatment
- Robotics and Sensor-Based Localization
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging and Analysis
- Burn Injury Management and Outcomes
- Reconstructive Surgery and Microvascular Techniques
- Advanced NMR Techniques and Applications
- Medical Imaging Techniques and Applications
- Osteoarthritis Treatment and Mechanisms
- Orthopedic Surgery and Rehabilitation
- MRI in cancer diagnosis
- Total Knee Arthroplasty Outcomes
- Atomic and Subatomic Physics Research
- 3D Shape Modeling and Analysis
- NMR spectroscopy and applications
University Medical Center Freiburg
2014-2024
University of Freiburg
2014-2024
University of Münster
1993-2023
Garmisch-Partenkirchen Medical Center
2023
Technische Hochschule Mittelhessen
2023
Orthopädische Universitätsklinik
2020
University Hospital Münster
2020
Dakota State University
2019
University of Minnesota
2019
University of Toronto
2019
<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> This paper presents a comparison study between 10 automatic and six interactive methods for liver segmentation from contrast-enhanced CT images. It is based on results the "MICCAI 2007 Grand Challenge" workshop, where 16 teams evaluated their algorithms common database. A collection of 20 clinical images with reference segmentations was provided to train tune in advance. Participants were also...
Although numerous procedures have been described for the reconstruction of anterior and posterior cruciate ligaments, there has little evaluation viability strength these substitutes. Using microangiographic, histological, biomechanical techniques, we studied vascularity tensile medial one-third patellar tendon at intervals after it had inserted as a substitute either or ligament in twenty-nine young adult Rhesus monkeys. For (nineteen knees), used elongated by portion patella. (ten...
A reactive synovitis secondary to intra-articular particles of silicone elastomer developed in three patients who had undergone Silastic hemiarthroplasty. In an attempt duplicate this phenomenon, we used animal model which finely ground particulate was introduced into the knee joints adult New Zealand White rabbits. thirteen rabbits (p = 0.066) histological evidence inflammatory changes synovial tissue, similar those seen our patients. Intraarticular created by abrasion a hemiarthroplasty...
Over the last few years, awareness of autism spectrum disorder (ASD) in adults has increased. The precise etiology ASD is still unresolved. Animal research, genetic and postmortem studies suggest that glutamate (Glu) system an important role, possibly related to a cybernetic imbalance between neuronal excitation inhibition. To clarify possible disruption Glu metabolism with high-functioning autism, we performed magnetic resonance spectroscopy (MRS) study investigating anterior cingulate...
Stress fractures of the great toe sesamoids have not been previously confirmed as a clinical entity. In this report, we present four such cases, and document diagnosis by histological sections. All patients had experienced insidious onset activity-related forefoot pain, radiographs that demonstrated sesamoid fracture. None healed with 6 weeks immobilization prolonged (4-6 months) inactivity. all fractured was excised, hematoxylin eosin sections fracture segments documented prefracture stress...
Heating of gradient coils and passive shim components is a common cause instability in the B0 field, especially when intensive sequences are used. The aim study was to set benchmark for typical drift encountered during MR spectroscopy (MRS) assess need real-time field-frequency locking on MRI scanners by comparing field data from large number sites. A standardized protocol developed 80 participating sites using 99 3T 3 major vendors. Phantom water signals were acquired before after an EPI...
Abstract The excitatory‐inhibitory imbalance hypothesis postulates dysregulation of the gamma‐aminobutyric acid (GABA) and glutamate (Glu) neurotransmitter systems as a common underlying deficit in individuals with autism spectrum disorders (ASD). Previous studies suggest an important role these pathophysiology ASD, including study our group reporting decreased concentrations pregenual anterior cingulate cortex (ACC) adults ASD. aim this was to replicate previous findings impaired metabolism...
In Brief Background: Intraoperative ultrasound is widely used in liver surgery, but primarily for diagnostic purposes. We have developed and evaluated a system navigated resections using on intraoperatively acquired 3-dimensional (3D) data. Methods: Navigation technique based 3D an optical tracking system. Accuracy of the was validated experimentally tumor model. Subsequently, clinical application 54 patients resection central tumors. Clinical feasibility accuracy navigation were assessed...
Acute mountain sickness is common among not acclimatized persons ascending to high altitude; the underlying mechanism unknown, but may be related cerebral edema. Nine healthy male students were studied before and after 6-h exposure isobaric hypoxia. Subjects inhaled room air enriched with N 2 obtain arterial O saturation values of 75 80%. was assessed environmental symptom questionnaire, edema 3 T magnetic resonance imaging in 18 regions interest white matter. The main outcome measures...
We reviewed the cases of twenty-four patients with solitary or multiple exostoses to correlate their radiographic, scintigraphic, and histological evaluations. studied twenty-five excised lesions, two them exostotic chondrosarcomas, from twenty-two patients. There were patterns bone-scan activity there was a direct correlation between enchondral bone formation radionuclide uptake in all patients, both skeletally immature mature. So-called quiescent lesions--those inactive scans--were those...
An instrument that measures pressures distribution during normal and unbalanced sitting was developed tested. Analysis of the pressure in fifteen patients showed approximately 18 per cent body weight is distributed over each ischial tuberosity; 21 cent, thigh; 5 sacrum. Three who had problems with balance foci unequal which are at risk for decubitus ulceration.
Abstract Localised two‐dimensional J ‐resolved spectroscopy ( PRESS) is optimised for the in vivo detection of ‐coupled metabolites using magnetic resonance at 3 T. The acquisition echo signals starts as early possible (i.e. maximum‐echo sampling). This sampling scheme increases sensitivity and decreases overlap peak tails, hence alleviating baseline problems. Reconstruction issues are discussed compared analytically with that 1D PRESS. qualitative behaviour eddy currents PRESS outlined a 2D...
Ceramic tricalcium phosphate (TCP) has been implanted in bony defects 43 patients following trauma. It is an osteoconductive material that facilitates trabecular bone formation. The average follow-up time was 12 months, with a 6-month minimum. There were 33 fractures 30 and 13 nonunions patients. Three of the acute unavailable for observation. Ninety percent 85% healed at this review. resorption TCP estimated from roentgenograms to be approximately 10% per month, complete occurring 6–24...