- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Advanced MRI Techniques and Applications
- Mental Health Research Topics
- Neural dynamics and brain function
- Advanced Neuroimaging Techniques and Applications
- Neuroscience and Music Perception
- Bipolar Disorder and Treatment
- Transcranial Magnetic Stimulation Studies
- Gastrointestinal motility and disorders
- Neural and Behavioral Psychology Studies
- Tryptophan and brain disorders
- Pathogenesis and Treatment of Hiccups
- Eosinophilic Esophagitis
- Advanced NMR Techniques and Applications
- Atomic and Subatomic Physics Research
- Electrochemical Analysis and Applications
- Lanthanide and Transition Metal Complexes
- NMR spectroscopy and applications
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Gastroesophageal reflux and treatments
- Neuroscience and Neuropharmacology Research
- Mental Health and Psychiatry
- Metabolomics and Mass Spectrometry Studies
- Music Therapy and Health
Columbia University Irving Medical Center
2017-2023
Centro de Investigación Biomédica en Red de Salud Mental
2014-2023
Johns Hopkins University
2020-2021
Medical Research Network
2021
Johns Hopkins Medicine
2021
Kennedy Krieger Institute
2020
Columbia University
2015-2019
Research Institute Hospital 12 de Octubre
2011-2016
Instituto de Salud Carlos III
2015
Hospital Clínico San Carlos
2008
Deficits in auditory emotion recognition (AER) are a core feature of schizophrenia and key component social cognitive impairment. AER deficits tied behaviorally to impaired ability interpret tonal (“prosodic”) features speech that normally convey emotion, such as modulations base pitch (F0M) variability (F0SD). These can be recreated using synthetic frequency modulated (FM) tones mimic the prosodic contours specific emotional stimuli. The present study investigates neural mechanisms...
Heating of gradient coils and passive shim components is a common cause instability in the B0 field, especially when intensive sequences are used. The aim study was to set benchmark for typical drift encountered during MR spectroscopy (MRS) assess need real-time field-frequency locking on MRI scanners by comparing field data from large number sites. A standardized protocol developed 80 participating sites using 99 3T 3 major vendors. Phantom water signals were acquired before after an EPI...
Abstract There is increasing focus on use of resting-state functional connectivity (RSFC) analyses to subtype depression and predict treatment response. To date, identification RSFC patterns associated with response electroconvulsive therapy (ECT) remain limited, focused interactions between dorsal prefrontal regions the limbic or default-mode networks. Deficits in visual processing are reported depression, however, within network have not been explored recent models depression. Here, we...
Transcranial magnetic stimulation (TMS) is an approved intervention for treatment-resistant depression (TRD), but current targeting approaches are only partially successful. Our objectives were (1) to examine the feasibility of MRI-guided TMS in clinical setting using a recently published surface-based, multimodal parcellation patients with TRD who failed standard (sdTMS); (2) neurobiological mechanisms and outcomes underlying compared that sdTMS. We used parcel-guided (pgTMS) target left...
Background The hardware and software differences between MR vendors individual sites influence the quantification of spectroscopy data. An analysis a large data set may help to better understand sources total variance in quantified metabolite levels. Purpose To compare multisite quantitative brain acquired healthy participants at 26 by using vendor-supplied single-voxel point-resolved (PRESS) sequence. Materials Methods protocol acquire short-echo-time PRESS from midparietal region was...
Health-related quality of life (HRQOL) is a main outcome in irritable bowel syndrome (IBS), but most studies have been conducted on moderate-severe patients. We sought to ascertain the relative contribution severity, anxiety, and personality impairment HRQOL sample representative entire IBS spectrum.IBS consulters, nonconsulters, controls were invited complete questionnaires designed measure severity (Functional Bowel Disease Severity Index), anxiety (State-trait Anxiety Inventory),...
<b><i>Background:</i></b> To assess insight in a large sample of patients with schizophrenia and to study its relationship set shifting as an executive function. <b><i>Methods:</i></b> The 161 clinically stable, community-dwelling was evaluated by means the Scale Assess Unawareness Mental Disorder (SUMD). Set measured using Trail-Making Test time required complete part B minus A (TMT B-A). Linear regression analyses were performed investigate...
Magnetic resonance imaging (MRI) has developed into an indispensible diagnostic tool in medicine. MRI also demonstrated immense potential for researchers who are making progress every aspect of this modality expanding its applications uncharted territories. Computational techniques have made major contributions to enabling detection minute signals from human brain. Functional (fMRI) offers the mind as well brain same session. Complex computational tools used visualize networks that offer a...