A5002336558- Breast Cancer Treatment Studies
- Breast Implant and Reconstruction
- Breast Lesions and Carcinomas
- Reconstructive Surgery and Microvascular Techniques
- Global Cancer Incidence and Screening
- Cancer Cells and Metastasis
- Cancer Treatment and Pharmacology
- HER2/EGFR in Cancer Research
- Ultrasound Imaging and Elastography
- BRCA gene mutations in cancer
- Photoacoustic and Ultrasonic Imaging
- Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Cancer Genomics and Diagnostics
- Genetic factors in colorectal cancer
- Ultrasound and Hyperthermia Applications
- Radiomics and Machine Learning in Medical Imaging
- Microfluidic and Bio-sensing Technologies
- Vascular Malformations and Hemangiomas
- Advances in Oncology and Radiotherapy
- Cancer Risks and Factors
- Histiocytic Disorders and Treatments
- Bone health and treatments
- Nonmelanoma Skin Cancer Studies
- Reconstructive Facial Surgery Techniques
Breast Center
2017-2025
University of Basel
2017-2025
University Hospital of Basel
2015-2025
Olgahospital
2019
Universitäts Frauenklinik
2016
Spital STS
2010
Abstract The presence of circulating tumor cell (CTC) clusters is associated with disease progression and reduced survival in a variety cancer types. In breast cancer, preclinical studies showed that inhibitors the Na + /K ATPase suppress CTC block metastasis. Here we conducted prospective, open-label, proof-of-concept study women metastatic where primary objective was to determine whether treatment inhibitor digoxin could reduce mean cluster size. An analysis nine patients treated daily...
Abstract Circulating tumour cell (CTC) clusters have been proposed to be major players in the metastatic spread of breast cancer, particularly during advanced disease stages. Yet, it is unclear whether or not they manifest early as their occurrence patients with metastasis-free primary has thoroughly evaluated. In this study, exploiting nanostructured titanium oxide-coated slides for shear-free CTC identification, we detect clustered CTCs curative setting multiple cancer prior surgical...
Demand for nipple- and skin- sparing mastectomy (NSM/SSM) with immediate breast reconstruction (BR) has increased at the same time as indications post-mastectomy radiation therapy (PMRT) have broadened. The aim of Oncoplastic Breast Consortium initiative was to address relevant questions arising this clinically challenging scenario.A large global panel oncologic, oncoplastic reconstructive surgeons, patient advocates oncologists developed recommendations clinical practice in an iterative...
Objectives Pelvic congestion syndrome is defined as chronic pelvic pain due to incompetent (dilated and refluxing) veins. The aim of this study was investigate the prevalence condition by examining dilated ovarian para-uterine veins in pre- postmenopausal female patients, irrespective their symptoms. We subsequently investigated how many women with suffered from pain. Additionally, we attempted define diagnostic criteria that may allow for early identification affected patients. Methods...
Cancer patients with advanced disease are characterized by intrinsic challenges in predicting drug response patterns, often leading to ineffective treatment. Current clinical practice for treatment decision-making is commonly based on primary or secondary tumour biopsies, yet when progression accelerates, tissue biopsies not performed a regular basis. It this context that liquid may offer unique window uncover key vulnerabilities, providing valuable information about previously...
Oncoplastic breast conserving surgery is increasingly used to treat patients with cancer. In the absence of randomized data, a large body observational evidence consistently indicates low rates recurrence and high survival, but points higher rate complications compared conventional surgery. Established goals oncoplastic are broaden indication for conservation towards larger tumors, improve esthetic outcomes. The benefit from patient's perspective, however, remains largely be confirmed. There...
Some studies have indicated age-specific differences in quality of life (QoL) among breast cancer (BC) patients. The aim this study was to compare patient-reported outcomes after conventional and oncoplastic surgery two distinct age groups.Patients who underwent for stage I-III BC, between 6/2011-3/2019, were identified from a prospectively maintained database. QoL evaluated using the Breast-Q questionnaire. Comparisons made women < 60 ≥ years.One hundred thirty-three patients included....
The Choosing Wisely initiative recommended the omission of routine sentinel lymph node biopsy (SLNB) in patients ≥ 70 years age, with clinically node-negative, early stage, hormone receptor (HR) positive and human epidermal growth factor 2 (Her2) negative breast cancer August 2016. Here, we assess adherence to this recommendation a Swiss university hospital.We conducted retrospective single center cohort study from prospectively maintained database. Patients 18 age node-negative were treated...
Neoadjuvant systemic treatment (NST) is the standard for HER2+, triple-negative (TN), and highly proliferative luminal HER2− early breast cancer. Pathologic complete response (pCR) after NST associated with improved outcomes. We evaluated predictive factors axillary-pCR (AXpCR) its impact on extent of axillary node surgery. This retrospective study included 92 patients (median age 50.4 years) an initially node-positive disease. Patients were treated molecular subtype-specific (4.3% A-like,...
To assess the risk for preterm deliveries <37 week of gestation and associated prevalence vaginal infection in a rural setting after tsunami Banda Aceh, Indonesia.Wet mount microscopy, pH swabs microbiological culture were collected pregnant women during 2nd trimester from February to June 2005 four temporary outpatient clinics patients followed up until delivery.One hundred fifty-nine screened. Sixty-two could be delivery. Thirty-nine (62.9%) delivered at term 23 (37.1%) prematurely....
<b><i>Background:</i></b> The aim of this study was to compare the risk complications and recurrence between oncoplastic conventional breast surgery. <b><i>Methods:</i></b> This is a retrospective analysis consecutive series 436 patients with stage I–III cancer who underwent surgery at University Hospital Basel 2011 2018. <b><i>Results:</i></b> nipple/skin-sparing mastectomy (NSM/SSM) group showed significantly more...
Postoperative complications after breast cancer surgery may be associated with decreased quality of life. It remains unclear whether oncoplastic breast-conserving or mastectomy reconstruction lead to more postoperative than conventional (CBS). As delayed wound healing (DWH) is one the most frequent minor complications, we sought investigate significance DWH for patient-reported outcomes oncoplastic, reconstructive, and CBS.Our study a retrospective cohort consecutive patients stage I-II who...
// Marcus Vetter 1,* , Spyridon Fokas 2,* Ewelina Biskup 3,7 Thomas Schmid 4 Fabienne Schwab 2 Andreas Schoetzau Uwe Güth 5 Christoph Rochlitz 1 and Rosanna Zanetti-Dällenbach 6 Department of Medical Oncology, University Hospital Basel, Switzerland Women’s Hospital,University 3 Internal Medicine, The Royal Marsden Hospital, London, United Kingdom Brust-Zentrum Zurich, Sankt Claraspital, 7 Shanghai Medicine Health Sciences, Basic College, Shanghai, PR China * These authors...
This study aims to compare patient-reported outcomes (PROs) after different types of oncoplastic surgery (OPS) procedures and correlate the results with previously published normative data from women no prior history breast cancer (BC) surgery.Cross-sectional patients stage I-II BC undergoing a specific selection OPS 04/2012 12/2018 by three surgeons at single tertiary referral hospital in Switzerland. PROs were evaluated using postoperative BREAST-Q questionnaire.One hundred twenty-seven...