A5039057543- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Breast Implant and Reconstruction
- Reconstructive Surgery and Microvascular Techniques
- Radiomics and Machine Learning in Medical Imaging
- Cancer and Skin Lesions
- Cancer Treatment and Pharmacology
- AI in cancer detection
- Advanced Breast Cancer Therapies
- Cancer Genomics and Diagnostics
- Cancer Diagnosis and Treatment
- Lymphatic System and Diseases
- Soft tissue tumor case studies
- HER2/EGFR in Cancer Research
- Cancer Immunotherapy and Biomarkers
- Global Cancer Incidence and Screening
- Cancer survivorship and care
- Cancer-related cognitive impairment studies
- BRCA gene mutations in cancer
- Advances in Oncology and Radiotherapy
- COVID-19 and healthcare impacts
- Medical Imaging Techniques and Applications
- Frailty in Older Adults
- Cancer Cells and Metastasis
- Tumors and Oncological Cases
Agostino Gemelli University Polyclinic
2018-2025
Università Cattolica del Sacro Cuore
2018-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2024
Weatherford College
2022
Breast Center
2020
Background: Implant-based breast reconstruction (IBBR) following conservative mastectomy is the most common approach for women undergoing cancer surgery. The aim of this study was to compare oncological outcomes combined with prepectoral IBBR subpectoral technique. Methods: clinical and demographic data consecutive patients who underwent either or between January 2018 December 2023 were retrospectively analyzed. primary outcome impact on local recurrence-free survival (LRFS). Secondary...
Sentinel lymph node biopsy (SLNB) has emerged as the standard procedure to replace axillary dissection (ALND) in breast cancer (BC) patients undergoing neo-adjuvant chemotherapy (NAC). SLNB is accepted clinically node-negative (cN0) patients; however, its role node-positive (cN+) debatable.We performed a retrospective analysis of BC NAC and SLNB. Our aim was evaluate clinical significance setting NAC. This accomplished by comparing characteristics oncological outcomes between cN0 cN+ prior...
Background: The aim of this study was to compare outcomes immediate prosthetic breast reconstruction (IPBR) using traditional submuscular (SM) positioning implants versus prepectoral (PP) micropolyurethane-foam-coated (microthane) without further coverage. Methods: We retrospectively reviewed the medical records cancer patients treated by nipple-sparing mastectomy (NSM) and IPBR in our institution during two-year period from January 2018 December 2019. Patients were divided into two groups...
Mesenchymal tumors of the breast represent a rare and diverse group neoplasms, accounting for 0.5% all tumors. These originate from mesenchymal tissues encompass variety histological subtypes. Malignant are particularly aggressive, characterized by high propensity local recurrence an overall poor prognosis. The rarity these cases has hindered development robust clinical studies, resulting in lack standardized diagnostic treatment guidelines considerable variability management. This review...
Introduction Up to one-fifth of breast cancer survivors will develop chronic cancer-related lymphoedema (BCRL). To date, complex physical decongestion therapy (CDT) is the gold standard treatment. However, it mainly symptomatic and often ineffective in preventing BCRL progression. Lymphovenous anastomosis (LVA) vascularised lymph node transfer (VLNT) are microsurgical techniques that aim restore lymphatic drainage. This international randomised trial aims evaluate advantages interventions...
Background: Breast cancer in women aged 80 years and older accounts for about 12% of cases, but its management is challenging due to the population’s heterogeneity lack relevant evidence-based guidelines. Treatment decisions must consider biological age, comorbidities, life expectancy, therapy-related toxicities, tumor biology. This study evaluates clinical outcomes elderly breast patients treated with a multidisciplinary approach, including oncologists, surgeons, geriatric specialists....
Conservative mastectomy with immediate prosthetic breast reconstruction (IPBR) is an oncologically accepted technique that offers improved esthetic results and patient quality of life. Traditionally, implants have been placed in a submuscular (SM) plane beneath the pectoralis major muscle (PMM). Recently, prepectoral (PP) placement prosthesis has increasingly used order to avoid morbidities related manipulation PMM. The aim this study was compare outcomes SM vs. PP IPBR after conservative...
Conserving surgery in inflammatory breast cancer after neoadjuvant chemotherapy patients with clinical complete response: the ConSIBreC randomized controlled trial
Oncoplastic surgery (OPS) has demonstrated its superiority above traditional breast conserving surgery, but is still struggling to consolidate role in cancer therapeutic protocols mainly because of contrasting scientific evidences and reduced follow-up results available. The objective our contribution analyze obtained with 381 patients consecutively treated Multidisciplinary Breast Center by means level II OPS between January 1998 2018 for unilateral, primary cancer. Surgical endpoints were...
Sentinel lymph node biopsy (SLNB) following neoadjuvant treatment (NACT) has been questioned by many studies that reported heterogeneous identification (IR) and false negative rates (FNR). As a result, some patients receive axillary dissection (ALND) regardless of response to NACT, leading potential overtreatment. To better assess reliability clinical significance SLNB status on ycN0 patients, we retrospectively analyzed oncological outcomes 399 treated between January 2016 December 2019...
Oncoplastic surgery level II techniques (OPSII) are used in patients with operable breast cancer. There is no evidence regarding their safety and efficacy after neoadjuvant chemotherapy (NAC). The aim of this study was to compare the oncological aesthetic outcomes technique compared those observed mastectomy immediate reconstruction (MIBR), post-NAC undergoing between January 2016 March 2021. Local disease-free survival (L-DFS), regional (R-DFS), distant (D-DFS), overall (OS) were compared;...
Oncoplastic level II breast-conserving surgery (OPS2) allows for wider excisions than standard surgery, but the literature on this technique in treatment of DCIS is scarce. This study compares OPS2 to conservative mastectomy (CM) patients undergoing large DCIS. The clinical, radiological, surgical, and post-operative data 147 who underwent either CM or between 2007 2021 were retrospectively reviewed. oncological, patient-reported outcomes (PRO) analyzed compared two groups. surgical similar,...
Triple-negative breast cancers (TNBC) include a heterogeneous group of diseases, characterized by the lack estrogen receptor (ER), progesterone (PgR), and human epidermal growth factor 2 (HER2) expression. TNBC that shows an overexpression androgen (AR) defines phenotype known as "luminal receptor" (LAR), while absence AR "quadruple negative cancer" (QNBC). Several reports have associated positivity with lower response to neoadjuvant chemotherapy (NAC), divergent data been reported about...
In this retrospective study we share our single-center experience using a magnetic seed for the preoperative localization of non-palpable breast lesions. Patients who underwent with Magseed® (Endomagnetics, Cambridge, UK) placement between 2020 and 2022 were enrolled. Indications to Magseed have been established during multidisciplinary meetings prior surgery all patients breast-conserving (BCS). 45 included. Magnetic seeds introduced under ultrasound guidance in 40 (88.9%) stereotactic 5...