A5082362428- Reconstructive Surgery and Microvascular Techniques
- Lymphatic System and Diseases
- Reconstructive Facial Surgery Techniques
- Breast Cancer Treatment Studies
- Bone fractures and treatments
- Breast Implant and Reconstruction
- Sympathectomy and Hyperhidrosis Treatments
- Nanoplatforms for cancer theranostics
- Body Contouring and Surgery
- Anatomy and Medical Technology
- Pelvic and Acetabular Injuries
- Soft Robotics and Applications
- Surgical site infection prevention
- Diagnosis and Treatment of Venous Diseases
- Trauma Management and Diagnosis
- Vascular Procedures and Complications
- Electrospun Nanofibers in Biomedical Applications
- Lymphatic Disorders and Treatments
- Surgical Simulation and Training
- Surgical Sutures and Adhesives
- Systemic Sclerosis and Related Diseases
- Facial Nerve Paralysis Treatment and Research
- Orthopedic Surgery and Rehabilitation
- Photoacoustic and Ultrasonic Imaging
- Microbial Metabolic Engineering and Bioproduction
Maastricht University
2016-2025
Maastricht University Medical Centre
2018-2025
Hangzhou Dianzi University
2020-2023
Soochow University
2017-2023
Eindhoven University of Technology
2021
University Medical Center
2018-2021
Central China Normal University
2021
Fujian Agriculture and Forestry University
2020
Chang Gung Memorial Hospital
2014-2020
Chang Gung University
2014-2020
A novel, high-capacity oil sorbent consisting of polyvinyl chloride (PVC)/polystyrene (PS) fiber was prepared by an electrospinning process. The sorption capacity, oil/water selectivity, and mechanism the PVC/PS were studied. results showed that capacities for motor oil, peanut diesel, ethylene glycol 146, 119, 38, 81 g/g, respectively. It about 5–9 times a commercial polypropylene (PP) sorbent. also had excellent selectivity (about 1000 times) high buoyancy in cleanup over water. SEM...
Theranostic nanoagents are promising for precision medicine. However, biodegradable with the ability photoacoustic (PA) imaging guided photothermal therapy (PTT) rare. We herein report development of semiconducting polymer nanoparticles (SPNs) enhanced PA and PTT efficacy cancer therapy. The design capitalizes on enzymatically oxidizable nature vinylene bonds in conjunction chemistry to synthesize a (DPPV) transform it into water-soluble (SPNV). As compared its counterpart SPN (SPNT),...
Abstract Advancements in reconstructive microsurgery have evolved into supermicrosurgery; connecting vessels with diameter between 0.3 and 0.8 mm for reconstruction of lymphatic flow vascularized tissue transplantation. Supermicrosurgery is limited by the precision dexterity surgeon’s hands. Robot assistance can help overcome these human limitations, thereby enabling a breakthrough supermicrosurgery. We report first-in-human study robot-assisted supermicrosurgery using dedicated...
Abstract Breast cancer related lymphedema (BCRL) is a chronic condition with detrimental impact on psychosocial and physical well-being. Lymphaticovenous anastomosis has shown promising results in alleviating symptoms increasing quality of life patients BCRL. The aim the study to evaluate effect health (HrQol) after LVA surgery versus conservative treatment prospective, multicenter randomized controlled trial. Adult women unilateral BCRL, early stage viable lymphatic vessels were included....
A bioinspired pine-branch-like TiO<sub>2</sub> membrane for high efficiency strong corrosive acidic, basic and salt emulsion separation.
Robotic assistance in microsurgery could enhance human precision and dexterity to improve clinical outcomes. Because no robotic device has been designed primarily for microsurgery, the authors developed a dedicated microsurgical system. This preclinical study investigates whether anastomosis can be successfully completed on silicone vessels using prototype of this new system, compares outcomes robot-assisted versus conventional microsurgery.Three participants at different levels training 10...
Lymphaticovenous anastomosis, a supermicrosurgical technique, creates bypasses between the lymphatic and venous systems. The quality of lymphaticovenous anastomosis depends on surgeon's dexterity precision, is subject to imperfections caused by physiologic tremor human hand. A dedicated robot for microsurgery has been created overcome these limitations (MUSA, MicroSure, Eindhoven, Netherlands). This study describes 1-year clinical outcomes first-in-human trial robot-assisted manual in...
Abstract Rapid clearance of nanoagents is a critical criterion for their clinical translation. Herein, it reported that biodegradable and renal clearable nanoparticles are potentially useful image‐guided photothermal therapy tumors. The multifunctional with excellent colloidal stability synthesized through coordination reactions between Fe 3+ ions gallic acid (GA)/polyvinyl pyrrolidone (PVP) in aqueous solution. Detailed characterization reveals the resulting /GA/PVP complex (FGPNs)...
Lymphedema is a chronic and disabling sequel of breast cancer treatment that can be treated by lymphatico-venous anastomosis (LVA). Artificial connections between the venous lymphatic system are performed supermicrosurgically. This prospective study analyses effect LVA on quality life. A was November 2015 July 2016 consecutive patients in Maastricht University Medical Centre. Quality life considered as primary outcome, International Classification Functioning (Lymph-ICF) questionnaire used....
CaWRKY40 was previously found to be transcriptionally up-regulated by Ralstonia solanacearum inoculation (RSI) or heat stress (HS), but the underlying mechanism remains unknown. Herein, we report that a double-W box-element (DWE) in promoter of is critical for these responses. The upstream W box unit WI this composite element crucial preferential binding and responsiveness RSI HS. DWE-driven can nonspecifically regulated itself CaWRKY58 CaWRKY27. DWE also promoters orthologs, including...
Abstract Purpose Breast cancer-related lymphedema (BCRL) is caused by an interruption of the lymphatic system after breast cancer treatment. Lymphaticovenous anastomosis (LVA), which one or more patent collecting vessels are connected to subcutaneous veins, shows promising results. Postoperatively, patency these can be evaluated; however, little known concerning long-term LVA in patients with BCRL. The aim this study was analyse patency, quality life (QoL) and arm circumference LVA, explore...
Here we present the FHIRM-TPM 3.0, a 2.6 g miniature two-photon microscope capable of multicolor deep-brain imaging in freely behaving mice. The system was integrated with broadband anti-resonant hollow-core fiber featuring low transmission loss, minimal dispersion from 700-1060 nm, and high tolerance laser power. By correcting chromatic spherical aberrations optimizing fluorescence collection aperture, achieved cortical neuronal at depths exceeding 820 μm and, using GRIN lens, hippocampal...
Introduction Up to one-fifth of breast cancer survivors will develop chronic cancer-related lymphoedema (BCRL). To date, complex physical decongestion therapy (CDT) is the gold standard treatment. However, it mainly symptomatic and often ineffective in preventing BCRL progression. Lymphovenous anastomosis (LVA) vascularised lymph node transfer (VLNT) are microsurgical techniques that aim restore lymphatic drainage. This international randomised trial aims evaluate advantages interventions...
Background: The purpose of this study was to compare the transverse rectus abdominis myocutaneous (TRAM) pedicled flap with a muscle and fascia–sparing based on deep inferior epigastric perforator (DIEP) in total vaginal reconstruction. authors studied advantages disadvantages both flaps. Methods: From January 1986 July 2010, 75 patients who underwent pelvic exenteration for gynecologic cancer were retrospectively reviewed. Sixty-two had recurrent disease 13 primary tumors. Forty...