A5057791743- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Lymphatic System and Diseases
- Breast Implant and Reconstruction
- Wound Healing and Treatments
- Mesenchymal stem cell research
- Body Contouring and Surgery
- Orthopedic Surgery and Rehabilitation
- Breast Cancer Treatment Studies
- Advancements in Transdermal Drug Delivery
- Bone Tissue Engineering Materials
- Nonmelanoma Skin Cancer Studies
- Dermatology and Skin Diseases
- Bee Products Chemical Analysis
- Vascular Malformations and Hemangiomas
- Peripheral Nerve Disorders
- Sympathectomy and Hyperhidrosis Treatments
- BRCA gene mutations in cancer
- Diagnosis and Treatment of Venous Diseases
- Body Image and Dysmorphia Studies
- Cancer and Skin Lesions
- Bone fractures and treatments
- Surgical Sutures and Adhesives
- Cancer Genomics and Diagnostics
- Chemotherapy-related skin toxicity
Aristotle University of Thessaloniki
2016-2025
Papageorgiou General Hospital
2015-2024
Interbalkan Medical Center
2015-2024
Creative Commons
2017-2020
Christie's
2020
I-Shou University
2019
E-Da Hospital
2019
Yahoo (United Kingdom)
2018
424 General Military Hospital
2018
Hellenic Cooperative Oncology Group
2016-2018
Secondary lymphedema is a common postcancer treatment complication, but the underlying pathological processes are poorly understood and no curative exists. To investigate pathomechanisms, top-down approach was applied, using genomic data validating role of single target. RNA sequencing lymphedematous mouse skin indicated upregulation many T cell-related networks, indeed depletion CD4+ cells attenuated lymphedema. The significant Foxp3, transcription factor specifically expressed by...
Microneedle (MN) patches are gaining increasing attention as a cost-effective technology for delivering drugs directly into the skin. In present study, two different 3D printing processes were utilized to produce coated MNs, namely, digital light processing (DLP) and semisolid extrusion (SSE). Donepezil (DN), cholinesterase inhibitor administered treatment of Alzheimer's disease, was incorporated coating material. Physiochemical characterization MNs confirmed successful incorporation...
Extravasation injuries are a common and challenging problem in hospitalized newborns. Accidental infusion leakage into the surrounding tissues immature infants may frequently result skin necrosis, with significant risk of functional cosmetic impairment.In present study we reviewed 34 cases severe extravasation occurring 1,409 neonates single neonatal unit over 24 months (incidence 2.4%). Total parenteral nutrition solutions were involved most cases. All patients treated within 30 minutes...
Ulvan, a bioactive natural sulfated polysaccharide, and gelatin, collagen-derived biopolymer, have attracted interest for the preparation of biomaterials different biomedical applications, due to their demonstrated compatibility cell attachment proliferation. Both ulvan gelatin exhibited osteoinductive potential, either alone or in combination with other materials. In current work, series novel hybrid scaffolds based on crosslinked was designed, prepared characterized. Their mechanical...
Introduction Up to one-fifth of breast cancer survivors will develop chronic cancer-related lymphoedema (BCRL). To date, complex physical decongestion therapy (CDT) is the gold standard treatment. However, it mainly symptomatic and often ineffective in preventing BCRL progression. Lymphovenous anastomosis (LVA) vascularised lymph node transfer (VLNT) are microsurgical techniques that aim restore lymphatic drainage. This international randomised trial aims evaluate advantages interventions...
The purpose of this prospective experimental and clinical study is to evaluate the effectiveness intralesional injection platelet‐rich plasma (PRP), in management non‐healing chronic wounds. Skin defects were created ears 20 white New Zealand rabbits. In group, autologous PRP was injected intralesionally. control group treated conservatively. Nineteen out cases healed within a mean time 24·9 days. seven period 26·7 days, ulcers did not heal at day 28 six full thickness ear defect recorded....
We used additive manufacturing to fabricate 3D-printed polycaprolactone scaffolds of different geometry topologies and porosities. present a comparative analysis hyaline cartilage development from adipose-tissue-derived mesenchymal stem cells (ADMSCs) on three different, newly designed scaffold patterns. The first design (MESO) was based rectilinear layer pattern. For the second pattern (RO45), we employed 45° rotational loop. for third (3DHC) three-dimensional honeycomb-like with hexagonal...
Hybrid composites of synthetic and natural polymers represent materials choice for bone tissue engineering. Ulvan, a biologically active marine sulfated polysaccharide, is attracting great interest in the development novel biomedical scaffolds due to recent reports on its osteoinductive properties. Herein, series hybrid polycaprolactone containing ulvan either alone or blends with κ-carrageenan chondroitin sulfate was prepared characterized. The impact preparation methodology polysaccharide...
In the current study, coated microneedle arrays were fabricated by means of digital light processing (DLP) printing. Three different shapes designed, printed, and with PLGA particles containing two actives. Rivastigmine (RIV) N-acetyl-cysteine (NAC) coformulated via electrohydrodynamic atomization (EHDA), they incorporated into particles. The actives are administered as a combined therapy for Alzheimer's disease. printed evaluated regarding their ability to penetrate skin mechanical...
The combined use of a deep inferior epigastric perforator (DIEP) flap coupled with vascularized inguinal lymph nodes (VILN) for simultaneous breast and lymphedema reconstruction has already been well established, promising results have reported. However, standardized approach the planning shaping this is still lacking. We aim to propose comprehensive algorithmic delayed unilateral using predesigned abdominal associated lymph-node transfer. present in detail preoperative measurements surgical...