A5034326513- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Lung Cancer Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Prostate Cancer Diagnosis and Treatment
- Chemotherapy-induced cardiotoxicity and mitigation
- Radiation Therapy and Dosimetry
- Prostate Cancer Treatment and Research
- Advances in Oncology and Radiotherapy
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Research Studies
- Polyomavirus and related diseases
- MRI in cancer diagnosis
- Brain Metastases and Treatment
- Cardiovascular Function and Risk Factors
- Effects of Radiation Exposure
- Cancer Treatment and Pharmacology
- Mobile Health and mHealth Applications
- Cancer Immunotherapy and Biomarkers
- Endometrial and Cervical Cancer Treatments
- Cancer Genomics and Diagnostics
- Protein Degradation and Inhibitors
- Cancer therapeutics and mechanisms
- HER2/EGFR in Cancer Research
- Transplantation: Methods and Outcomes
The University of Texas Southwestern Medical Center
2016-2025
Southwestern Medical Center
2024
Harold C. Simmons Comprehensive Cancer Center
2022
In this commentary, we describe the potential of highly ablative doses utilizing Stereotactic Body Radiation Therapy (SBRT) in single or few fractions to enhance immune-responsiveness, how timing approach combination with immune-checkpoint inhibitors may augment treatment-effect, and whether Personalized Ultrafractionated Adaptive (PULSAR) is an avenue for future advancement continued endeavor foster a systemic effect therapy beyond radiation treatment field. The SBRT support increase...
Abstract Purpose Describe an early‐adopting institution's experience with online adaptive radiation for stereotactic partial breast irradiation. Methods and materials Retrospective review of 22 women treated between May 2021 March 2022 A total 106 110 fractions were evaluated dosimetric changes in target coverage organ‐at‐risk (OAR) dose. Patient set up wooden frame adapted per fraction. Treatment planning times collected prospectively by therapists. Results Scheduled PTV 30 Gy was <95%...
Adaptive radiotherapy has the potential to reduce margins, improve target coverage, and decrease toxicity organs at risk (OARs) by optimizing radiation delivery daily anatomic changes. Salvage for locally recurrent prostate cancer after definitive remains a challenging clinical scenario given risks normal tissue in setting of re-irradiation. Here, we present case series five patients with treated an adaptive online linear accelerator or 3-T MR-based demonstrate excellent coverage. All...
Breast irradiation has evolved significantly over the last several decades. Accelerated partial breast and stereotactic have as strategies to reduce irradiated volumes, preserve appropriate oncologic control, improve cosmetic outcome. The sequencing and/or combination of with novel systemic agents is great interest community. Here we explore landscape modern trials opine on future irradiation.
Active breathing coordinator (ABC)-assisted deep inspiration breath hold (DIBH) is an important organ sparing radiation therapy (RT) technique for left-sided breast cancer patients. Patients with advanced undergoing chest wall and regional nodal irradiation often require a field matching technique. While has been demonstrated to be safe effective in free patients, its safety accuracy DIBH/ABC use not previously reported.To report the accuracy, feasibility, of ABC/DIBH patients receiving...
Background and purposeRadiation-induced erectile dysfunction (RiED) commonly affects prostate cancer patients, prompting clinical trials across institutions to explore dose-sparing internal-pudendal-arteries (IPA) for preserving sexual potency. IPA, challenging segment, isn't conventionally considered an organ-at-risk (OAR). This study proposes a deep learning (DL) auto-segmentation model using Computed Tomography (CT) Magnetic Resonance Imaging (MRI) or CT alone accommodate varied...
Abstract Objectives To quantify the intra-fraction tumor bed motion using image guidance and fiducial markers to determine optimal PTV margins in early-stage breast cancer patients receiving adaptive radiation therapy SPBI after partial mastectomy. Methods A retrospective cohort of five with pT1a-pT2N0, grade 1-2, ER+/PR+ invasive ductal carcinoma either right or left underwent mastectomy adjuvant five-fraction cone beam based online adaptation. total 62 CBCTs 22 fractions were analyzed...
Background and purpose: Radiation-induced erectile dysfunction (RiED) is commonly seen in prostate cancer patients. Clinical trials have been developed multiple institutions to investigate whether dose-sparing the internal-pudendal-arteries (IPA) will improve retention of sexual potency. The IPA usually not considered a conventional organ-at-risk (OAR) due segmentation difficulty. In this work, we propose deep learning (DL)-based auto-segmentation model for that utilizes CT MRI or alone as...