A. Lucas

ORCID: 0000-0003-1526-022X
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About
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Research Areas
  • Glioma Diagnosis and Treatment
  • Brain Metastases and Treatment
  • Hematopoietic Stem Cell Transplantation
  • Congenital Anomalies and Fetal Surgery
  • Immune Cell Function and Interaction
  • Management of metastatic bone disease
  • Injury Epidemiology and Prevention
  • Hernia repair and management
  • Gun Ownership and Violence Research
  • Acute Lymphoblastic Leukemia research
  • Acute Myeloid Leukemia Research
  • Congenital Diaphragmatic Hernia Studies
  • COVID-19 Clinical Research Studies
  • Vascular Procedures and Complications
  • COVID-19 and healthcare impacts
  • COVID-19 Impact on Reproduction
  • Lung Cancer Treatments and Mutations
  • Oral health in cancer treatment
  • Chemotherapy-related skin toxicity
  • Psoriasis: Treatment and Pathogenesis
  • Testicular diseases and treatments
  • Immunotherapy and Immune Responses
  • Gynecological conditions and treatments
  • Diphtheria, Corynebacterium, and Tetanus
  • Ethics and Legal Issues in Pediatric Healthcare

Carol Davila University of Medicine and Pharmacy
2025

Memorial Sloan Kettering Cancer Center
2020-2024

Princess Máxima Center
2023-2024

Hôpital Cochin
2021-2024

Centre Hospitalier Sud Francilien
2024

Assistance Publique – Hôpitaux de Paris
2022-2023

Université Paris Cité
2021-2023

Cornell University
2023

Weill Cornell Medicine
2023

Délégation Paris 5
2022

CD4 immune reconstitution (IR) after allogeneic hematopoietic cell transplant (allo-HCT) correlates with lower non-relapse mortality (NRM), but its impact on leukemia relapse remains less clear, especially in children. We studied the correlation between IR of lymphocyte subsets and HCT outcomes a large cohort children/young adults hematological malignancies.

10.1016/j.jcyt.2023.05.012 article EN cc-by Cytotherapy 2023-06-16

Abstract Allogeneic hematopoietic cell transplantation (HCT) remains the only cure for hematologic manifestations of Fanconi anemia (FA). We performed retrospective predictor analyses HCT outcomes in FA pediatric and young adult patients transplanted between 2007 2020 across three large referral institutions. Eighty-nine patients, 70 with bone marrow failure +/− cytogenetic abnormalities, 19 MDS/AML, were included. Five-year overall survival (OS) was 83.2% event-free (EFS) 74%. Age ≥19, HLA...

10.1038/s41409-023-02121-1 article EN cc-by Bone Marrow Transplantation 2023-10-17

Purpose The purpose of this study was to compare the technical success rate, selectivity transarterial chemoembolization (TACE), complication radiation dose given patients and hospitalization stay between TACE performed using femoral artery approach (FAA) radial (RAA) in with hepatocellular carcinoma (HCC). Methods Between June 2020 April 2022, 49 HCC who underwent 116 TACEs (75 FAA 41 RAA) were included. Differences micro-catheterization, patients, fluoroscopy time, duration, rate compared...

10.1177/08465371231186524 article EN Canadian Association of Radiologists Journal 2023-08-10

Background Patients with leukemia relapse after allogeneic hematopoietic cell transplant (HCT) have poor survival due to toxicity and disease progression. A second HCT often offers the only curative treatment. Methods We retrospectively reviewed our bi-institutional experience (MSKCC-USA; Utrecht-NL) unrelated cord blood transplantation (CBT) for treatment of post-transplant relapse. Overall (OS) event-free (EFS) were evaluated using Kaplan-Meier method, treatment-related mortality (TRM)...

10.3389/fonc.2023.1221782 article EN cc-by Frontiers in Oncology 2023-08-15

PURPOSE Gun violence is a leading cause of injury deaths in children the United States. The American Academy Pediatrics (AAP) states that “the absence guns from children’s homes and communities” most effective means to prevent firearm injuries children. Bright Futures guidelines recommends pediatricians provide gun safety education caregivers beginning infancy. However, few this important prevention education. Asking Saves Kids (ASK) campaign, promoted by AAP, encourages ask if there where...

10.1542/peds.142.1_meetingabstract.730 article EN PEDIATRICS 2018-05-01

The purpose of this study was to report the effectiveness preoperative transcatheter arterial embolization (TAE) musculoskeletal tumors in terms blood loss and functional outcomes. Patients who underwent TAE hypervascular between January 2018 December 2021 were retrospectively included. patients’ characteristics, procedure details, degree post-TAE devascularization, surgical outcomes red cell transfusion results collected. devascularization compared patients had peri-operative those did not....

10.3390/cancers15092657 article EN Cancers 2023-05-08

Varicocele embolization is an effective, minimally invasive treatment option, with a symptom improvement rate of around 90%. However, anatomical variations and post-embolization recurrences pose challenges to its efficacy. This article discusses the antegrade technique as viable alternative for cases in which retrograde fails, offering broader spectrum options varicocele.

10.1186/s42155-024-00446-6 article EN cc-by CVIR Endovascular 2024-06-27

In EORTC study 22033−26033 primary treatment with radiotherapy was compared to temozolomide chemotherapy alone in patients high-risk low-grade glioma. There no difference progression-free survival between modalities [Baumert et al. Lancet Oncol. 2016;17:1521-1532]. Considering the potential long-term deleterious impact of on memory functioning, this also focused question whether would be associated a more favorable neurotoxic profile regarding functioning. Memory functioning using Rey...

10.1093/neuonc/nox168.568 article EN Neuro-Oncology 2017-11-01

Background: Little is known about the effect of COVID-19 disease on pediatric hematology, oncology and hematopoietic stem cell transplant (HCT) patients.Methods: We identified all patients < 21 years age tested for infection at Memorial Sloan Kettering Cancer Center (MSK) HCT programs Columbia University Irving Medical Weill Cornell Center, both affiliated with New York Presbyterian Hospital (NYP), from March 10 through April 6, 2020. Demographic, clinical presentation, course treatment data...

10.2139/ssrn.3582825 article EN SSRN Electronic Journal 2020-01-01

INTRODUCTION: Low grade gliomas (LGG) comprise nearly 20% of all central nervous system (CNS) glial tumors. LGG are characterized by their infiltrative growth and frequent tumor recurrence with malignant progression. They have a heterogeneous clinical behavior being histological, first line resection, velocity diameter expansion during pretherapeutic period,tumor volume, contrast enhancement patients' characteritics the only described factors for identifying patients at risk The...

10.1093/neuonc/nou174.64 article EN Neuro-Oncology 2014-09-01

Ureteroarterial fistula (UAF) is a rare but life-threatening condition because of massive hemorrhage. Risk factors include degenerative vascular diseases, previous surgery, pelvic radiation, chemotherapy, and prolonged ureteral stenting. The most common presentation UAF hematuria with hemorrhagic shock. diagnosis always difficult even angiography. Endovascular repair stenting and/or coiling effective safe. surgical treatment should be used in recurrent cases. We reported case describing...

10.1177/15385744221105817 article EN Vascular and Endovascular Surgery 2022-05-25

10.4267/2042/69481 article FR cc-by-nc-nd Bulletin de l Académie vétérinaire de France 1950-01-01
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