A5100321621- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Innovative Microfluidic and Catalytic Techniques Innovation
- Photoacoustic and Ultrasonic Imaging
- Metal complexes synthesis and properties
- Ultrasound and Hyperthermia Applications
- Metal Extraction and Bioleaching
- Minerals Flotation and Separation Techniques
- Electrowetting and Microfluidic Technologies
- Gold and Silver Nanoparticles Synthesis and Applications
- Extraction and Separation Processes
- Electrospun Nanofibers in Biomedical Applications
- Angiogenesis and VEGF in Cancer
- Microfluidic and Capillary Electrophoresis Applications
- Luminescence Properties of Advanced Materials
- Microfluidic and Bio-sensing Technologies
- Advanced Nanomaterials in Catalysis
- Phytochemistry and Bioactivity Studies
- Luminescence and Fluorescent Materials
- Natural product bioactivities and synthesis
- Fluorine in Organic Chemistry
- Cancer therapeutics and mechanisms
- Polyoxometalates: Synthesis and Applications
- Gallbladder and Bile Duct Disorders
- Nanocluster Synthesis and Applications
Nanjing University
2024-2025
First Affiliated Hospital of Zhengzhou University
2023-2024
Central South University
2023-2024
Dalian University of Technology
2021-2024
Southwest University of Science and Technology
2022-2024
University of Shanghai for Science and Technology
2022-2024
Liaoning Normal University
2024
State Key Laboratory of Pollution Control and Resource Reuse
2024
Nanjing University of Aeronautics and Astronautics
2023
Nanjing Tech University
2022
Abstract X-ray-induced photodynamic therapy utilizes penetrating X-rays to activate reactive oxygen species in deep tissues for cancer treatment, which combines the advantages of and radiotherapy. Conventional usually requires heavy-metal-containing inorganic scintillators organic photosensitizers generate singlet oxygen. Here, we report a more convenient strategy based on class phosphorescence nanoscintillators, that act dual capacity as photosensitizers. The resulting low dose 0.4 Gy...
Four novel heteropolyoxonibate-based inorganic–organic hybrids {Cu(en)2}6{GeNb12VIV2O42}·20H2O (1), {Cu(en)2}3K2Na4{GeNb12VIV2O42}·23H2O (2), {Cu(en)2}6{SiNb12VIV2O42}·18H2O (3), and {Cu(en)2}3K2Na4{SiNb12VIV2O42}·19H2O (4) (en = ethanediamine), composed of polyoxoanions [TNb12O40]16– (T Si Ge) [Cu(en)2]2+ building blocks, were successfully synthesized under hydrothermal conditions by reaction K7HNb6O19·13H2O, Cu(Ac)2·3H2O, Na2VO3, Na2SiO3, or GeO2 en molecules. Polyoxoanion...
The present work deals with a challenge in the synthesis of aryltrifluoromethyliodanes (ArICF3X) and develops direct route to PhICF3Cl via simple ligand-exchange reaction PhI(OCOCF3)2, Me3SiCF3, NaCl for first time. I-Cl bond length supports its iodonium character, which enables an enhanced CF3-transfer capability electrophilic S-, O-, N-, C-trifluoromethylations as well catalyst-free trifluoromethylation-cyclizations arylisonitriles.
A multifunctional hybrid platinum(IV) prodrug, which consists of both the mitochondria-targeting drug DCA and DNA-crosslinking cisplatin, was synthesized tethered to a carrier polymer further self-assemble into micelles for intracellular delivery.
Streptococcus mutans has been reported as a primary cariogenic pathogen associated with dental caries. The bacteria can produce glucosyltransferases (Gtfs) to synthesize extracellular polysaccharides (EPSs) that are known virulence factors for adherence and formation of biofilms. Therefore, an ideal inhibitor caries is one inhibit planktonic growth prevent biofilm formation. Bergenia crassifolia (L.), widely used folk medicine tea beverage, have variety bioactivities. present study aimed...
A novel strategy for combination chemotherapy (platinum and demethylcantharidin) via a polymer-(tandem drugs) conjugate enhanced cancer treatment is demonstrated. Cisplatin can be released inside cell by reduction to attack DNA, while DMC will hydrolyzed subsequently block DNA-damage-induced defense mechanisms serine/threonine phosphatase PP2A inhibition. Synergistic effect of the causes complete suppression H22 liver tumor xenografts without recurrence.
Melanoma is a primary reason of death from skin cancer and associated with high lethality. Photothermal therapy (PTT) has been developed into powerful treatment technique in recent years. Here, we created low-cost high-performance PTT agent, Ag@TiO2 NPs, which possesses photothermal conversion efficiency ≈65 % strong near-infrared (NIR) absorption about 808 nm. Ag NPs were synthesized using two-step method coated TiO2 to obtain by facile sol-gel method. Because the oxide, exhibit remarkable...
The capacity to specifically destroy cancer cells while avoiding normal tissue is urgently desirable in treatment. Herein, a photothermal-trigger-released system serves as photoacoustic imaging agent constructed by entrapping diketopyrrolopyrrole-based conjugated polymers and curcumin poly(ethylene glycol) (PEG)-protected thermoresponsive liposomal phospholipid bilayer. This lipid nanostructure can improve the bioavailability of hydrophobic agents for photothermal treatment with high...
Integrating nanostructured active materials, antimicrobial components, and rational porous structures is one of the promising approaches for simultaneously boosting removal efficiency, capacity, mechanical property, hydrophobic performance, air permeability filters. However, realizing these performances an filter still remains a big challenge. Herein, multifunctional zNFs-Ag@PT, which composed unique substrate prepared from Ag nanoparticles (AgNPs)-paper towel (PT) microfibers upper layer...
In the field of one-step efficient preparation dewetting droplet arrays, process is hampered by requirement for low chemical wettability solid surfaces, which restricts complete transition wetting state and its broad prospects in biological applications. Inspired physical structure lotus leaf, enabling it to promote change infiltration an aqueous solution on surface, we developed a method fabrication arrays biomimetic structural chip designed present work. This greatly reduces need...