Chengyu Wu

ORCID: 0000-0003-1547-3516
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About
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Research Areas
  • Advancements in Transdermal Drug Delivery
  • Advanced Drug Delivery Systems
  • Perovskite Materials and Applications
  • Conducting polymers and applications
  • Cancer Research and Treatments
  • biodegradable polymer synthesis and properties
  • Skin Protection and Aging
  • Organic Light-Emitting Diodes Research
  • Dyeing and Modifying Textile Fibers
  • Nanoparticle-Based Drug Delivery
  • RNA Interference and Gene Delivery
  • Cancer Cells and Metastasis
  • Cancer, Hypoxia, and Metabolism
  • Organic Electronics and Photovoltaics
  • Olfactory and Sensory Function Studies
  • Phytochemicals and Antioxidant Activities
  • Ionic liquids properties and applications
  • melanin and skin pigmentation
  • Geochemistry and Geologic Mapping
  • Biochemical Analysis and Sensing Techniques
  • Photochromic and Fluorescence Chemistry
  • Geological and Geochemical Analysis
  • Lipid Membrane Structure and Behavior
  • Electrospun Nanofibers in Biomedical Applications
  • Crystal Structures and Properties

Nanjing University of Chinese Medicine
2013-2025

Taiwan Semiconductor Manufacturing Company (Taiwan)
2025

Harbin Institute of Technology
2021-2024

Southwest University
2022-2024

Shenzhen Technology University
2024

Shantou University
2024

First Affiliated Hospital of Shantou University Medical College
2024

Shandong University
2024

South China Agricultural University
2024

National Tsing Hua University
2023

Ti3C2Tx MXene is a new type of two-dimensional material with good biocompatibility and photothermal effect, shows great potential in cancer treatment. In this study, few-layer ionic liquid (IL)-Ti3C2Tx nanosheets were synthesized using IL stripping technology, which have high chemical stability, allow photoacoustic imaging synergistic photothermal/chemotherapy cancer. Under 808 nm laser irradiation, the strong absorption near-infrared region, conversion efficiency (∼63.91%). Using DOX as...

10.1039/d1tb01938d article EN Journal of Materials Chemistry B 2022-01-01

The successful treatment of infected wounds requires strategies with effective antimicrobial, anti-inflammatory, and healing-promoting properties. Accordingly, the use Cu2+ tetracycline (TC), which can promote angiogenesis, re-epithelialization, collagen deposition, also antibacterial activity, at wound site, has shown application prospects in promoting repair. However, realizing controllable release to prolong action time avoid potential toxicities is critical. Moreover, near-infrared light...

10.1021/acsami.1c19209 article EN ACS Applied Materials & Interfaces 2022-01-05

Abstract Hole transporting materials (HTMs) are imperative for promoting the development of perovskite solar cells (PSCs). Herein, three isomers RQ4, RQ5, and RQ6 constructed by methylthio (‐SMe) group in para, meta, adjacent sites terminal benzene on side‐chain carbazole‐arylamine derivatives based HTMs, investigated means theoretical simulation experimental characterization. As a result simulation, isomeric HTMs RQ4‐RQ6 exhibit appropriate highest occupied molecular orbital /lowest...

10.1002/adfm.202213843 article EN Advanced Functional Materials 2023-01-18

Abstract BACKGROUND Hormonal therapy is effective for advanced prostate cancer (PC) but the disease often recurs and becomes hormone‐refractory. It hypothesized that a subpopulation of cells, is, stem cells (CSCs), survives hormonal leads to tumor recurrence. CD44 expression was shown identify with CSC features. PC contains secretory type epithelial minor population neuroendocrine cells. Neuroendocrine do not express androgen receptor are quiescent, features associated CSCs. The purpose...

10.1002/pros.20928 article EN The Prostate 2009-02-02

To improve the effect of pine rosin in plant fungicides, four series dehydroabietyl-1,3,4-thiadiazole derivatives from natural product were synthesized. Based on evaluation vitro antifungal activity against Sclerotinia sclerotiorum, Botrytis cinerea, Fusarium oxysporum, and Magnaporthe oryzae, rosin-based 1,3,4-thiadiazole compounds containing thiophene heterocycles screened. Notably, compound 3e [dehydroabietyl-(1,3,4-thiadiazol-2-yl)-5-nitrothiophene-2-carboxamide] exhibited excellent...

10.1021/acs.jafc.1c01887 article EN Journal of Agricultural and Food Chemistry 2021-06-02

Tumor is one of the most serious forms abnormal growth that endangers human health today; its morbidity and mortality are both increasing every year. Most antitumor drugs used currently cannot be absorbed well by body because their poor solubility low bioavailability. Therefore, prevention treatment tumors still high significance. These challenges can addressed use ionic liquids (ILs). Half in market salts linked together ILs. Compared to solid form drug, salt liquid at room temperature or...

10.1021/acssuschemeng.1c01064 article EN ACS Sustainable Chemistry & Engineering 2021-04-23

RNA-binding proteins (RBPs) refer to a class of that participate in alternative splicing, RNA stability, polyadenylation, localization and translation RNAs, thus regulating gene expression post-transcriptional manner. Dysregulation RNA-RBP interaction contributes various diseases, including cancer. In breast cancer, disorders RBP function influence the biological characteristics tumor cells. Targeting RBPs has fostered development innovative therapies for However, RBP-related mechanisms...

10.1016/j.critrevonc.2024.104271 article EN cc-by-nc-nd Critical Reviews in Oncology/Hematology 2024-01-23

Gravi-A nanoparticles, composed of retinyl propionate (RP) and hydroxypinacolone retinoate (HPR), were prepared by encapsulating the two using high-pressure homogenization technique. The nanoparticles are effective in anti-wrinkle treatment with high stability low irritation. We evaluated effect different process parameters on nanoparticle preparation. Supramolecular technology effectively produced spherical shapes an average size 101.1 nm. encapsulation efficiency was 97.98–98.35% range....

10.3390/pharmaceutics15030731 article EN cc-by Pharmaceutics 2023-02-22

Evidence mapping was used to systematically analyze the clinical research evidence of oral Chinese patent medicines in treatment intracerebral hemorrhage(ICH), thus revealing distribution and quality this field. The relevant articles were retrieved from CNKI, Wanfang, VIP, SinoMed, PubMed, EMbase, Cochrane Library, Web Science inception July 5, 2024. characteristics presented numerically graphically. A total 35 identified, involving 261 articles. basic information medicines, publication...

10.19540/j.cnki.cjcmm.20241009.501 article EN PubMed 2025-01-01

Formulation of protein and peptide drugs with sustained release properties is crucial to enhance their therapeutic effect minimize administration frequency. In this study, immunomodulating polymeric systems were designed by manufacturing PHBHHx nanoparticles (NPs) containing thymopentin (TP5). The profile the drug was studied over a period 7 days. NPs TP5-phospholipid (PLC) complex (TP5-PLC) displayed spherical shape mean size, zeta potential, encapsulation efficiency 238.9 nm, −32.0 mV,...

10.1021/mp400722r article EN Molecular Pharmaceutics 2014-03-18

To explore risk factors for no-reflow phenomenon after percutaneous coronary intervention in patients with acute syndrome.A total of 733 myocardial infarction persistent ischemic chest pain within 12 or 12-24 hours onset received emergency intervention. Patients were divided into a normal reflow group and group, according to TIMI grading blush Related analyzed.The incidence was 16.1%. Univariate analysis showed that, compared the older, reperfusion time significantly longer, preoperative...

10.24875/ric.17002190 article EN Revista de investigaci�n Cl�nica 2017-05-24
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