A5046971744- Cardiac electrophysiology and arrhythmias
- Cardiovascular Disease and Adiposity
- COVID-19 Clinical Research Studies
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Cardiovascular Issues in Pregnancy
- Renal and Vascular Pathologies
- Cardiac pacing and defibrillation studies
- Sodium Intake and Health
- COVID-19 and healthcare impacts
- Heart Failure Treatment and Management
- Pregnancy-related medical research
- Blood Pressure and Hypertension Studies
- Cardiovascular Function and Risk Factors
- Nuclear Structure and Function
- Congenital heart defects research
- Pulmonary Hypertension Research and Treatments
Grigore T. Popa University of Medicine and Pharmacy
2024-2025
Infectious Diseases Institute
2024-2025
Background/Objectives: Chronic kidney disease (CKD) patients are at an increased risk for severe outcomes following a COVID-19 infection. However, the long-term impact of prior on survival in this population remains unclear. This study evaluates association between infection, echocardiographic parameters, and mortality CKD over 24-month follow-up period. Methods: A prospective cohort was conducted 239 patients, including those hemodialysis. Kaplan–Meier analysis Cox proportional hazards...
Background/Objectives: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused post-acute sequelae, especially for people with pre-existing conditions, including chronic kidney disease (CKD), which may impact the cardiovascular system. Yet, despite preliminary description of general population’s long-COVID-19 consequences, data on CKD patients is scarce. The aim this study was to investigate longitudinal effects COVID-19 echocardiographic parameters cardiac function and...
Hypertrophic cardiomyopathy (HCM) is a heterogeneous genetic disorder, most often caused by sarcomeric gene mutations, with small proportion due to variants in non-sarcomeric loci. Phospholamban (PLN) phosphoprotein associated the cardiac sarcoplasmic reticulum, major determinant of contractility and relaxation. We conducted retrospective study determine prevalence, phenotypical spectrum clinical course patients carrying PLN p.Leu39* variant. A cohort including 11 was identified among all...
Dilated cardiomyopathy (DCM) represents a group of disorders affecting the structure and function heart muscle, leading to high risk failure sudden cardiac death (SCD). DCM frequently involves an underlying genetic etiology. Genetic testing is valuable for stratification, treatment decisions, family screening. Romanian population data on etiology are lacking. We aimed investigate causes among adult patients at tertiary referral centers across country. Clinical investigations were performed...
Cardiovascular disease (CVD) and chronic kidney (CKD) often coexist have a major impact on patient prognosis. Organ fibrosis plays significant role in the pathogenesis of cardio-renal syndrome (CRS), explaining high incidence heart failure sudden cardiac death these patients. Various mediators mechanisms been proposed as contributors to alteration fibroblasts collagen turnover, varying from hemodynamic changes activation renin–angiotensin system, involvement FGF 23, Klotho protein or...