- Bacterial biofilms and quorum sensing
- Plasma Applications and Diagnostics
- Oral microbiology and periodontitis research
- Infective Endocarditis Diagnosis and Management
- Legionella and Acanthamoeba research
- Electrohydrodynamics and Fluid Dynamics
- Medical Device Sterilization and Disinfection
- Dental materials and restorations
- Hematological disorders and diagnostics
- Cardiovascular Effects of Exercise
- Aerosol Filtration and Electrostatic Precipitation
- Antimicrobial agents and applications
- Bone and Dental Protein Studies
- Microbial Community Ecology and Physiology
- Infection Control and Ventilation
- Microplastics and Plastic Pollution
- Congenital limb and hand anomalies
- Periodontal Regeneration and Treatments
- Otolaryngology and Infectious Diseases
- Hematopoietic Stem Cell Transplantation
- Indoor Air Quality and Microbial Exposure
- Clinical Laboratory Practices and Quality Control
- Water Treatment and Disinfection
- Oral Health Pathology and Treatment
- dental development and anomalies
Université de Reims Champagne-Ardenne
1999-2023
Centre Hospitalier Universitaire de Reims
1999-2023
Biomatériaux et Bioingénierie
1999-2018
Biomatériaux et Inflammation en Site Osseux
1999-2018
Laboratoire des Biomolécules
2000-2006
Inserm
2006
Hôpital Charles-Nicolle
2004
In this work, we developed a device capable to generate non-thermal plasma discharge inside sealed bag. The aim of study was assess the effectiveness oxygen, nitrogen and argon sterilization on Pseudomonas aeruginosa, Staphylococcus aureus Bacillus subtilis spores according NF EN 556 Norm. Moreover bag integrity which is critical key maintain sterile state items after end process verified by Fourier Transform Infrared (FTIR) X-ray Photoelectron Spectrometry (XPS) analyses. After treatments,...
Inherited dental malformations constitute a clinically and genetically heterogeneous group of disorders. Here, we report on four families, three them consanguineous, with an identical phenotype, characterized by significant short stature brachyolmia hypoplastic amelogenesis imperfecta (AI) almost absent enamel. This phenotype was first described in 1996 Verloes et al. as autosomal recessive form associated AI. Whole-exome sequencing resulted the identification hypomorphic mutations including...
The Coulter LH 750® is a new haematology analyser with several features: count of nucleated red blood cells (NRBCs), automated WBC correction in presence flag indicating cellular interference and lower incidence platelet or flags when compared the GEN.S, our current instrument. We had three main goals study: evaluating 750 counts GEN.S suggests risk interference, ascertaining whether not flagged by were accurately assessed samples NRBC assay provided 750. Flow cytometry, using CD45 CD41,...
We have recently developed a non-thermal plasma (NTP) equipment intended to sterilize fragile medical devices and maintain the sterile state of items downstream treatment. With traditional counts on agar plate six log reduction Staphylococcus aureus viability was obtained within 120 min O2, Ar, or N2 NTP treatments. However determine best process, we studied different physiological states S. by flow cytometry (FC) confocal laser scanning microscopy (CLSM) focusing esterasic activity membrane...
The sterilization of medical devices is paramount to achieve an acceptable level sterility assurance and prevent hospital-acquired infections. However, some cannot be sterilized by usual processes such as autoclave (AC) gamma-ray irradiation (GI). A new non-thermal plasma (NTP) process using sealed bag that preserves the sterile state could used alternative method. aim study was assess cytocompatibility titanium poly(etheretherketone) (PEEK) surfaces after O2-NTP compared GI AC. MG-63...
As the worldwide population has been experiencing since 2020, viruses represent a serious threat to global well-being. To avoid viral transmission through surgery or medical examination, sterilization of material is needed. From emerging processes, use non-thermal plasma (NTP) arises as promising technique efficiently reduce microbial burden on devices, including new complex polymers thermosensitive ones. Thus, we evaluated antiviral efficacy low-pressure NTP process taking place in sealed...
Denture stomatitis is a disease involving C. albicans, which can affect elderly and immuno-compromised people. To avoid any recurrence of this pathology, it necessary to treat patients regularly disinfect dentures. However, the denture cleansers’ efficacy not optimal often leads adverse color effects on base resins. The aim study was investigate low-pressure non-thermal O2 plasma (NTP) treatment albicans seeded ProBase®Hot resin (Ivoclar Vivadent). viability reduction assessed by colony...
A new de novo heterozygous mutation in the desmoplakin gene, causing Naxos and Carvajal disease, has been reported a 13-year-old Caucasian girl, with expanded clinical phenotype. In addition to woolly hair, palmoplantar keratoderma cardiomyopathy, she had oligodontia nail fragility. These additional features may help diagnosis of known be severe on cardiac level.