A5010762574- Advanced Radiotherapy Techniques
- Endometrial and Cervical Cancer Treatments
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Radiation Dose and Imaging
- Lung Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Radiation Therapy and Dosimetry
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Colorectal and Anal Carcinomas
- Cervical Cancer and HPV Research
- Advanced X-ray and CT Imaging
- Head and Neck Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Ovarian cancer diagnosis and treatment
- Gastric Cancer Management and Outcomes
- Brain Metastases and Treatment
- Uterine Myomas and Treatments
- Pancreatic and Hepatic Oncology Research
- Urinary and Genital Oncology Studies
- Colorectal Cancer Surgical Treatments
- Oral health in cancer treatment
- Advances in Oncology and Radiotherapy
- Breast Cancer Treatment Studies
Tokushima University
2016-2025
Tokushima University Hospital
2011-2021
Okayama University
2011
The University of Texas MD Anderson Cancer Center
2008-2010
Hokkaido University
2009
National Cancer Center Hospital East
2000
Kyushu University
1994
Our purpose was to develop recommendations for contouring the computed tomography (CT)-based high-risk clinical target volume (CTVHR) 3D image-guided brachytherapy (3D-IGBT) cervical cancer. A 15-member Japanese Radiation Oncology Study Group (JROSG) committee with expertise in gynecological radiation oncology initiated guideline development CT-based CTVHR (based on a comprehensive literature review as well experience) July 2014. Extensive discussions occurred during four face-to-face...
We evaluated risk factors of radiation pneumonitis (RP) after whole breast irradiation following breast-conserving surgery. Four hundred and seventy-two cases underwent with tangential field surgery in our hospital, between January 2005 April 2007. Of these cases, we performed statistical analyses for 423 breasts 413 patients, using a pulmonary dose-volume histogram. Patient characteristics, treatment regimens methods were included as variables the on RP. As result, 89 84 (21%) diagnosed The...
We present two patients with a history of paroxysmal atrial fibrillation who developed pulmonary vein stenosis (PVS) following (AF) ablation. Case 1 involved female patient in her 50s was asymptomatic for symptoms but found to have high degree left superior PVS 15 months after AF This demonstrated using contrast-enhanced computed tomography (CE-CT) and supported by findings perfusion defects on ventilation-perfusion (V/Q) scan. 2 male his 60s progressive nine ablation, evidenced serial CE-CT...
To review the current status of, and labor expended for (in terms of time required), intracavitary brachytherapy (ICBT) in definitive radiotherapy/chemoradiotherapy cervical cancer patients, two national surveys were performed. The first survey was conducted between July August 2016 consisted a questionnaire 12 items regarding ICBT procedures cancer, which sent to 173 centers installed with high-dose-rate remote after-loading systems. Between November December 2016, another performed 79...
In cervical cancer treatment, radiation therapy is selected based on the degree of tumor progression, and oncologists are required to delineate contours. To reduce burden oncologists, an automatic segmentation contours would prove useful. best our knowledge, contour has rarely been applied treatment. this study, diffusion-weighted images (DWI) 98 patients with were acquired. We trained model using 2D U-Net 3D investigate possibility applying such a clinical practice. A total cases employed...
Hypoxia-inducible factor (HIF)-2α, a basic helix-loop-helix (bHLH)-PAS protein, is the principal regulator of hypoxic transcriptional response. An immunohistochemical study reported strong HIF-2α expression in cytoplasm tumor infiltrative macrophages (TIMs). Thus we assessed human cervical cancer tissue before radiation therapy and its relationship to clinical outcome. Seventy three patients with histologically proven primary advanced squamous cell carcinoma uterine cervix underwent...
The present study aimed to retrospectively evaluate the efficacy and toxicities of adjuvant chemotherapy with paclitaxel carboplatin (TC) following concurrent cisplatin-based chemoradiation (CCRT) in patients cervical cancer lymphadenopathy (N1). A total 37 FIGO stage IB2-IVA carcinoma N1 (median age 57 years, range 31-74 years) were enrolled. External beam radiation therapy was followed by high-dose-rate brachytherapy. In cases suspected para-aortic or common iliac lymph node involvement,...
It has been postulated that the combination of intracavitary and interstitial brachytherapy (IC/IS) is effective safe for large irregularly shaped uterine cervical cancer patients. However, due to its invasiveness compared conventional (ICBT), it be said implementation speed IC/IS slow. Until now, there have no guidelines required equipment, human resources, procedural guide focusing solely on IC/IS. The purpose this guideline provide radiation oncologists medical physicists who wish start...
The purposes of this trial were to demonstrate the feasibility and effectiveness hybrid intracavitary interstitial brachytherapy (HBT) for locally advanced cervical cancer patients in phase I/II prospective clinical trial.Patients with FIGO stage IB2-IVA uterine pretreatment width which was ≥5 cm measured by magnetic resonance imaging eligible trial. protocol therapy included 30-30.6 Gy 15-17 fractions whole pelvic radiotherapy concurrent weekly CDDP, followed 24 4 HBT a central shield up...
Abstract Purpose The purpose of this study was to assess the quality treatment planning using PlanIQ TM software and investigate whether it is possible improve “Feasibility dose‐volume histogram (DVH) ” implemented in software. Methods Using software, we retrospectively analyzed learning curve regarding plans for 148 patients prostate intensity‐modulated radiation therapy volumetric‐modulated performed at our institution over past eight years. We also sought examine possibility improving by...
The treatment period over which radiation therapy is administered extends several weeks. Since tumor shrinkage in response to and weight loss due radiation-induced mucositis may impact on the dose distribution both target organ at risk patients with head neck cancer, anatomical changes of volumes during this should be taken into consideration. We investigated that occurred normal structure for pharyngeal evaluated necessity an adaptive strategy. Ten cancer who underwent radical...
Background and purposePreoperative 5-fluorouracil-based chemoradiotherapy is a standard treatment for locally advanced lower rectal cancer (LALRC). We performed phase I study to develop new regimen combining irinotecan S-1.Materials methodsPatients with LALRC (T3-4, N0-2) were studied. The radiation dose was 45 Gy in 25 fractions. S-1 (80 mg/m2/day) administered on days 1–5, 8–12, 22–26, 29–33. Irinotecan 1, 8, 22, 29. of initially 60 mg/m2 (level 1). Surgery 6–10 weeks after the...
We retrospectively assessed whether magnetic resonance imaging (MRI) radiomics combined with clinical parameters can improve the predictability of out-of-field recurrence (OFR) cervical cancer after chemoradiotherapy. The data set was collected from 204 patients stage IIB (FIGO: International Federation Gynecology and Obstetrics 2008) who underwent chemoradiotherapy at 14 Japanese institutes. Of these, 180 were finally included for analysis. OFR-free survival calculated using Kaplan-Meier...
Compared with the implementation speed of image-guided adaptive brachytherapy for uterine cervical cancer, that intracavitary and interstitial is slow, possible because it requires more invasive procedure inserting needles directly into tumours. To accelerate brachytherapy, a first hands-on seminar cancer was held on 26 November 2022, supported by Japanese Society Radiology Oncology. This article deals this difference degree confidence participants in starting before after seminar.The...