A5037944118- Poisoning and overdose treatments
- Traumatic Ocular and Foreign Body Injuries
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Ocular Infections and Treatments
- Venomous Animal Envenomation and Studies
- Drug-Induced Adverse Reactions
- Plant-based Medicinal Research
- Retinal and Optic Conditions
- Biocrusts and Microbial Ecology
- Dermatological diseases and infestations
- Appendicitis Diagnosis and Management
- Musculoskeletal pain and rehabilitation
- Orthopedic Surgery and Rehabilitation
- Disaster Response and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Pelvic and Acetabular Injuries
- Cardiovascular Syncope and Autonomic Disorders
- Ocular Surface and Contact Lens
- Tardigrade Biology and Ecology
- Hematological disorders and diagnostics
- Cellular Mechanics and Interactions
- Chemotherapy-related skin toxicity
- Spine and Intervertebral Disc Pathology
- Cardiac electrophysiology and arrhythmias
McGill University
2024-2025
University of Kassel
2017-2023
University of Virginia
2002-2020
University of California, Santa Cruz
2020
University Clinic of Traumatology
2018
University Hospital Ulm
2018
Leipzig University
2012-2015
Penn State Milton S. Hershey Medical Center
2013
Johns Hopkins Hospital
2010
Hebrew University of Jerusalem
1996
Abstract Onychophorans use a unique hunting and defense strategy, which involves the ejection of an adhesive slime secretion produced by pair specialized glands. So far, comparative study on anatomy these glands has not been carried out among different species. In this article, we compare anatomical features in representatives two major onychophoran subgroups, Peripatopsidae Peripatidae, from parts world. Our data show that musculature reservoir is conserved whereas composition secretory...
Velvet worms eject a fluid capture slime that can be mechanically drawn into stiff biopolymeric fibres. Remarkably, these fibres dissolved by extended exposure to water, and new regenerated from the fibre solution-indicating fully recyclable process. Here, we perform multiscale structural compositional investigation of this reversible fabrication process with velvet worm Euperipatoides rowelli, revealing assembly is facilitated via mono-disperse lipid-protein nanoglobules. Shear forces cause...
Velvet worms secrete a fluid hunting slime comprised of dispersion nanoglobules that form microfibers under small mechanical shear forces, facilitating the rapid formation stiff biopolymeric fibers. Here, we demonstrate are held together and stabilized as by electrostatic interactions reminiscent coacervate-based natural adhesives. Variation ionic strength pH affects stability their ability to Fibers mainly consist large (∼300 kDa), highly charged proteins, current biochemical analysis...
Introduction. Massive caffeine overdose is associated with life‐threatening hemodynamic complications that present challenges for clinicians. We describe the highest‐reported serum concentration of in a patient who survived and discuss first‐reported use vasopressin hemodialysis caffeine‐poisoned patient. Case Report. A 41‐yr‐old woman presented 3 h after ingesting approximately 50 g caffeine. She subsequently underwent cardiopulmonary resuscitation received multiple medications an attempt...
Natural materials provide an increasingly important role model for the development and processing of next-generation polymers. The velvet worm Euperipatoides rowelli hunts using a projectile, mechanoresponsive adhesive slime that rapidly reversibly transitions into stiff glassy polymer fibers following shearing drying. However, molecular mechanism underlying this behavior is still unclear. Previous work showed to be emulsion nanoscale charge-stabilized condensed droplets comprised primarily...
The slime of velvet worms (Onychophora) is a protein-based bioadhesive that undergoes rapid, yet reversible transition from fluid into stiff fibers used for prey capture and defense, but the mechanism by which this phase functions largely unknown. Here, integrating transcriptomic proteomic approaches with AI-guided structure predictions, we discover group evolutionarily conserved leucine-rich repeat (LRR) proteins in worm readily adopt receptor-like, protein-binding “horseshoe” structure....
Onychophorans are carnivorous, terrestrial invertebrates that occur in tropical and temperate forests of the Southern Hemisphere around Equator. Together with tardigrades, onychophorans regarded as one closest relatives arthropods. One most peculiar features is their hunting feeding behavior. These animals secrete a sticky slime, which ejected via pair slime-papillae, to entangle prey. After prey has been immobilized, its cuticle punctured using jaws located within mouth. constitute...
Nature is rich with examples of highly specialized biological materials produced by organisms for functions, including defense, hunting, and protection. Along these lines, velvet worms (Onychophora) expel a protein-based slime used hunting defense that upon shearing dehydration forms fibers as stiff thermoplastics. These can dissolve back into their precursor proteins in water, after which they be drawn new fibers, providing inspiration to design recyclable materials. Elevated phosphorus...
Onychophorans (velvet worms) use an adhesive, protein-based slime secretion for prey capture and defence. The glue-like is ejected via a pair of modified limbs the sticky threads entangle victim. In this study, we analysed protein composition in twelve species Onychophora from different parts world, including two Peripatidae Costa Rica Brazil ten Peripatopsidae Australia, using sodium dodecyl sulphate polyacrylamide gel electrophoresis. Our results revealed high intraspecific conservation...
The functions of secreted animal mucuses are remarkably diverse and include lubricants, wet adhesives, protective barriers, mineralizing agents. Although present in all animals, many open questions related to the hierarchical architectures, material properties, genetics mucus remain. Here, we summarize what is known about structure, describe work research groups throughout world who investigating various mucuses, relate how these studies revealing new properties relationships between...
Abstract For prey capture and defense, velvet worms eject an adhesive slime which has been established as a model system for recyclable complex liquids. Triggered by mechanical agitation, the liquid bio‐adhesive rapidly transitions into solid fibers. In order to understand this mechanoresponsive behavior, here, nanostructural organization of components are studied using small‐angle scattering with neutrons X‐rays. The intensities successfully described three‐component accounting proteins two...
Many organisms have evolved a capacity to form biopolymeric fibers outside their bodies for functions such as defense, prey capture, attachment, and protection. In particular, the adhesive capture slime of onychophorans (velvet worms) is remarkable its ability rapidly stiff through mechanical drawing. Notably, that are formed ex vivo from extracted can be dissolved in water new drawn solution, indicating fiber formation encoded biomolecules comprise slime. This review highlights recent...
In the past, some moonshine products contained potentially toxic contaminants. Although production continues in United States, no studies have analyzed content of since early 1960s. We hypothesize that to contain concentrations contaminants.Forty-eight samples illicitly distilled were obtained from law enforcement agencies. An independent laboratory, blinded both source and a control sample ethanol, conducted analysis. Lead was determined using atomic absorption spectrophotometry with...
California's coastal climate is characterized by rainy winters followed a dry summer season that supplemented frequent fog. While rising temperatures and drought caused massive tree mortality in central California during the 2011–2015 extreme drought, dying trees were less common coast region. We hypothesized cooler, maritime-ameliorated reduced effects of stress on vegetation. To test this, weekly measurements water potential stomatal conductance made two evergreen species, Arbutus...
Abstract The slime of velvet worms (Onychophora) is a protein-based bioadhesive that undergoes rapid, yet reversible transition from fluid into stiff fibers used for prey capture and defense, but the mechanism by which this phase functions largely unknown. Here, integrating transcriptomic proteomic approaches with AI-guided structure predictions, we discover group evolutionarily conserved leucine-rich repeat (LRR) proteins in worm readily adopt receptor-like, protein-binding “horseshoe”...