A5100365930- Nanoplatforms for cancer theranostics
- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Food Quality and Safety Studies
- Food Supply Chain Traceability
- Agriculture, Soil, Plant Science
- Photodynamic Therapy Research Studies
- bioluminescence and chemiluminescence research
- Luminescence and Fluorescent Materials
- Luminescence Properties of Advanced Materials
- Ruminant Nutrition and Digestive Physiology
- Influenza Virus Research Studies
- Nanopore and Nanochannel Transport Studies
- Bat Biology and Ecology Studies
- Viral Infections and Vectors
- Radiation Detection and Scintillator Technologies
- Turfgrass Adaptation and Management
- SARS-CoV-2 detection and testing
- Animal Disease Management and Epidemiology
- IoT and Edge/Fog Computing
- Pancreatic function and diabetes
- Animal Virus Infections Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Viral Infections and Immunology Research
- Blood transfusion and management
Hanyang University
2022-2025
Korea Institute of Science and Technology
2020
Korea University
2020
Korea University of Science and Technology
2020
Seoul National University
2017
Korea National Institute of Health
2013
Abstract Efficient pathogen enrichment and nucleic acid isolation are critical for accurate sensitive diagnosis of infectious diseases, especially those with low levels. Our study introduces a biporous silica nanofilms-embedded sample preparation chip enrichment/isolation. This features unique nanostructures comprising large small pore layers. Computational simulations confirm that these enhance the surface area promote formation nanovortex, resulting in improved capture efficiency. Notably,...
Near-infrared (NIR)-to-NIR upconversion nanoparticles (UCNPs) are promising materials for biomedical imaging and sensing applications. However, UCNPs with long lifetimes continue to face the limitation that they usually accompanied by weak luminescence intensity, resulting in difficulties achieving high-resolution sensitive time-gated imaging. To overcome this limitation, we have developed NIR long-lifetime luminescent (NLL NPs) strong 800 nm emission adding a photosensitizing shell...
Infectious disease viruses, such as foot-and-mouth virus (FMDV), are highly contagious viruses that cause significant socioeconomic damage upon spreading. Developing an on-site diagnostic tool for early clinical detection and real-time surveillance of FMDV outbreaks is essential to prevent the further spread disease. However, diagnosis still challenging due limited sensitivity time-consuming manual result entry commercial tests salivary samples. Here, we report a near-infrared (NIR) signal...
Abstract To resolve the problem of target specificity and light transmission to deep-seated tissues in photodynamic therapy (PDT), we report a cancer cell-targeted photosensitizer using photoprotein-conjugated upconversion nanoparticles (UCNPs) with high efficient deep tissues. Core-shell UCNPs low internal energy back transfer were conjugated recombinant proteins that consists (KillerRed; KR) lead peptide (LP). Under near infrared (NIR)-irradiating condition, UCNP-KR-LP generated superoxide...
Abstract The growing significance of information technology requires advanced storage and security solutions. While extending traditional 2D codes with additional parameters has led to promising 3D codes, increasing capacity remains challenging. Herein, a quick response (QR) cube platform that utilizes near‐infrared (NIR)‐to‐NIR upconversion nanoparticles as light‐emitting probes, benefiting from their photostability low scattering properties. These features enable precise reconstruction the...
<title>Abstract</title> Although upconversion nanoparticle (UCNP)-based luminescence resonance energy transfer (LRET) biosensing offers advantages such as wash-free detection and precise biomolecule quantification, there is still room for enhancing its sensitivity by preventing continuous in co-doped UCNPs during LRET. In this study, we report a time-gated LRET approach using near-infrared (NIR) long-lived luminescent UCNP donors (L-TG-LRET), achieving an 8-fold increase lifetime without...
Abstract To resolve the problem of target specificity and light transmission to deep-seated tissues in photodynamic therapy (PDT), we report a cancer cell-targeted photosensitizer using photoprotein-conjugated upconversion nanoparticles (UCNPs) with high efficient deep tissues. Core-shell UCNPs low internal energy back transfer were conjugated recombinant proteins that consists (KillerRed; KR) lead peptide (LP). Under near infrared (NIR)-irradiating condition, UCNP-KR-LP generated superoxide...
Abstract Efficient pathogen enrichment and nucleic acid (NA) isolation are critical for accurate sensitive diagnosis of infectious diseases, especially those with low levels. Our study introduces a biporous silica nanofilms-embedded sample preparation chip (BSNFs-chip) NA enrichment/isolation. The BSNFs-chip features unique nanostructures comprising large small pore layers. Computational simulations confirm that these enhance the surface area promote formation nanovortex, resulting in...