Lucas M. Abreu

ORCID: 0000-0003-1606-5709
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About
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Research Areas
  • Plant Pathogens and Fungal Diseases
  • Microbial Natural Products and Biosynthesis
  • Fungal Biology and Applications
  • Plant-Microbe Interactions and Immunity
  • Mycorrhizal Fungi and Plant Interactions
  • Plant and fungal interactions
  • Yeasts and Rust Fungi Studies
  • Microbial Metabolism and Applications
  • Mycotoxins in Agriculture and Food
  • Plant Pathogenic Bacteria Studies
  • Plant biochemistry and biosynthesis
  • Turfgrass Adaptation and Management
  • Synthesis and Biological Activity
  • Enzyme-mediated dye degradation
  • Bacterial biofilms and quorum sensing
  • Legume Nitrogen Fixing Symbiosis
  • Plant pathogens and resistance mechanisms
  • Microbial Metabolic Engineering and Bioproduction
  • Papaya Research and Applications
  • Bee Products Chemical Analysis
  • Plant Disease Resistance and Genetics
  • Enzyme Production and Characterization
  • Entomopathogenic Microorganisms in Pest Control
  • Microbial Community Ecology and Physiology
  • Agricultural and Food Sciences

Universidade Federal de Viçosa
2016-2025

Universidade Federal de São Paulo
2022

Universidade Metropolitana de Santos
2018

Universidade São Francisco
2018

Universidade Federal de Lavras
2006-2017

Technical University of Denmark
2015

Universidade Federal de Minas Gerais
2007-2011

Universidade Estadual Paulista (Unesp)
2007

Abstract A survey for species of the genus Trichoderma occurring as endophytes Coffea, and mycoparasites coffee rusts ( Hemileia ), was undertaken in Africa; concentrating on Cameroon Ethiopia. Ninety-four isolates were obtained during this study: 76 healthy leaves, stems berries and, 18 directly from colonized rust pustules. phylogenetic analysis all used a combination three genes: translation elongation factor-1α tef1 rpb2 cal selected isolates. GCPSR criteria recognition species;...

10.1038/s41598-021-84111-1 article EN cc-by Scientific Reports 2021-03-11

Despite the numerous benefits plants receive from probiotics, maintaining consistent results across applications is still a challenge. Cultivation-independent methods associated with reduced sequencing costs have considerably improved overall understanding of microbial ecology in plant environment. As result, now, it possible to engineer consortium microbes aiming for health. Such synthetic communities (SynComs) contain carefully chosen species produce desired microbiome function. Microbial...

10.1094/phyto-01-23-0016-ia article EN Phytopathology 2023-03-01

Production of pigments by filamentous fungi is gaining interest owing to their use as food colourants, in cosmetics and textiles, because the important biological activities these compounds. In this context, objectives study were select pigment-producing fungi, identify based on internal transcribed spacer sequences, evaluate growth pigment production selected strains four different media, characterize major coloured metabolites extracts. Of fungal strains, eight identified Aspergillus...

10.1099/mic.0.000168 article EN Microbiology 2015-09-04

Fusarium tupiense, the main causal agent of mango malformation in Brazil, is described through a combination morphological, biological and molecular markers. This new species belongs to Gibberella fujikuroi complex (GFSC) has an anamorph morphologically similar mangiferae F. sterilihyphosum. tupiense can be differentiated from other G. on basis sexual crosses, amplified fragment length polymorphism (AFLP) markers partial sequences tef1 tub2 genes. Female fertility for field isolates appears...

10.3852/12-052 article EN Mycologia 2012-11-01

Sclerotinia sclerotiorum is an important plant pathogen with worldwide distribution that causes severe economic losses of various agricultural crops such as soybean. This fungus normally controlled synthetic chemical fungicides pose risks to the environment, and can be harmful human health, they also induce resistance in pests. The aim this study was investigate potential Trichoderma asperelloides a biocontrol agent towards white mold disease on soybeans crops. antagonism two strains T. (T25...

10.1080/09583157.2018.1430743 article EN Biocontrol Science and Technology 2018-01-31

During surveys conducted in South America and Africa to identify natural fungal enemies of coffee leaf rust (CLR), Hemileia vastatrix, over 1500 strains were isolated, either as endophytes from healthy tissues Coffea species or mycoparasites growing on pustules. Based morphological data, eight isolates—three isolated wild semiwild five coffee, all Africa—were provisionally assigned the genus Clonostachys. A polyphasic study their morphological, cultural molecular characteristics—including...

10.3390/jof9020248 article EN cc-by Journal of Fungi 2023-02-13

Abstract Background Azo dyes in textile effluents represent a particular health concern because they include azo groups (NN), which are reactive with DNA nucleic acids. The enzymes produced by white rot fungi can biodegrade broad range of environmental contaminants. This work addresses this concentrating on novel and effective optimal conditions for Trametes cingulata to produce oxidative the capacity decolorize dye red 239. Results A multifactorial experimental design optimized enzymatic...

10.1002/jctb.7797 article EN Journal of Chemical Technology & Biotechnology 2025-01-08

The increased interest in secondary metabolites (SMs) has driven a number of genome sequencing projects to elucidate their biosynthetic pathways. As result, studies revealed that the metabolite gene clusters (SMGCs) greatly outnumbers detected compounds, challenging current methods dereplicate and categorize this amount on larger scale. Here, we present an automated workflow for genetic dereplication analysis metabolism genes fungi. Focusing rich genus Aspergillus, SMGCs across genomes into...

10.1038/s41598-018-36561-3 article EN cc-by Scientific Reports 2018-12-12

A fungal strain of Aspergillus niger was recovered from sediments collected in the Northeast coast Brazil (Pecém's offshore port terminal). Cultivation different growth media yielded a new ester furan derivative, 1, along with malformin A1, C, cyclo (trans-4-hydroxy-L-Pro-L-Leu), (trans-4-hydroxy-L-Pro-L-Phe), (L-Pro-L-Leu), (L-Pro-L-Phe), pseurotin D, A, chlovalicin, (L-Pro-L-Tyr) and (L-Pro-L-Val). Compound 1 cytotoxic against HCT-116 cell line, showing IC50 = 2.9 μg/mL (CI 95% 1.8 to 4.7 μg/mL).

10.1080/14786419.2017.1283499 article EN Natural Product Research 2017-01-30

Three new isoaigialones, A, B, and C (1–3), along with aigialone (4), were isolated from the crude EtOAc extract of a Phaeoacremonium sp., an endophytic fungus obtained leaves Senna spectabilis. The structures these compounds elucidated based on analysis spectroscopic data. Compounds 2 4 active against phytopathogenic fungi Cladosporium cladosporioides C. sphaerospermum. This is first report metabolites produced by associated S.

10.1021/acs.jnatprod.5b00828 article EN Journal of Natural Products 2017-04-20

A fungal strain of Aspergillus sp. (BRF 030) was isolated from the sediments collected in northeast coast Brazil, and cytotoxic activity its secondary metabolites investigated against HCT-116 tumour cell line. The cytotoxicity-guided fractionation extracts this fungus cultured potato-dextrose-sea water for 14 days at room temperature yielded hetero-spirocyclic γ-lactams pseurotin (1), D (2) FD-838 (7), alkaloids fumitremorgin C (5), 12,13-dihydroxy (6), methylsulochrin (4)...

10.1080/14786419.2014.987772 article EN Natural Product Research 2014-12-23

Abstract The cytotoxic activities of extracts (50 μg/ml) from 48 fungal strains, recovered sediments Pecém's offshore port terminal (Northeast coast Brazil), against HCT‐116 colon cancer cell lines were investigated. most promising extract was obtained strain BRF082, identified as Dichotomomyces cejpii by phylogenetic analyses partial RPB2 gene sequence. Thus, it selected for bioassay‐guided isolation the compounds. Large‐scale fermentation BRF082 in potato dextrose broth, followed...

10.1002/cbdv.201400193 article EN Chemistry & Biodiversity 2015-03-01

Abstract Early blight, caused by Alternaria solani and A . grandis , severely affects potato crops around the world, few management options apart from intensive fungicide use are available. In this work, we tested whether biocontrol treatments with different species of mycoparasitic fungus Clonostachys could reduce early blight severity on foliage pot‐grown potatoes cultivar Ágata, affect survival sporulation causal pathogen Twenty isolates five were screened in a preliminary trial, nine...

10.1111/ppa.13402 article EN Plant Pathology 2021-05-09

Bovine mastitis caused by S. aureus has a major economic impact on the dairy sector. With crucial need for new therapies, anti-virulence strategies have gained attention as alternatives to antibiotics. Here we aimed identify novel compounds that inhibit production/activity of hemolysins, virulence factor associated with severity. We screened Bacillus strains obtained from diverse sources showing anti-hemolytic activity. Our results demonstrate lipopeptides produced spp. completely prevented...

10.1038/s41598-024-58973-0 article EN cc-by Scientific Reports 2024-04-24
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