A5033840651- Probiotics and Fermented Foods
- Gut microbiota and health
- Reproductive tract infections research
- Microbial Metabolites in Food Biotechnology
- Diet and metabolism studies
- Bee Products Chemical Analysis
- Urinary Tract Infections Management
- Antimicrobial Peptides and Activities
- Protein Hydrolysis and Bioactive Peptides
- Immune Response and Inflammation
- Wound Healing and Treatments
- Digestive system and related health
- Pharmacological Effects of Natural Compounds
- Nutrition, Genetics, and Disease
- Seaweed-derived Bioactive Compounds
- Carbon and Quantum Dots Applications
- Diet, Metabolism, and Disease
- Advanced Nanomaterials in Catalysis
- Agriculture and Biological Studies
- Transgenic Plants and Applications
- Influenza Virus Research Studies
- Medical and Biological Ozone Research
- Animal Disease Management and Epidemiology
- Nanoparticles: synthesis and applications
- T-cell and Retrovirus Studies
Danylo Zabolotny Institute of Microbiology and Virology
2012-2023
Oles Honchar Dnipro National University
2009
Aim. To investigate changes in the phospholipid composition of bee body tissues under influence lyophilized probiotic strain Lactobacillus casei IMV B-7280 combination with nanotechnological Ge citrate laboratory conditions. Methods. The research was conducted on honey bees Carpathian breed. Bees control group were fed 60% sugar syrup amount 1 cm3/group/day. Experimental (E 1), addition to cm3 syrup, received 0.1 μg form and a solution L. at concentration 106 CFU/cm3; experimental 2 2), 0.2...
The antibacterial activity of Lactobacillus casei IMV B-7280, Lact. acidophilus B-7279, Bifidobacterium longum VK1, and B. bifidum VK2 strains or their various compositions in relation to Staphylococcus aureus vitro on models experimental intravaginal staphylococcosis mice was determined. It found that under the influence these compositions, growth Staph. inhibited, number colonies plated from vagina infected significantly reduced. separately correlated with ability improve performance...
The purpose of this study was to investigate the antimicrobial and immunomodulatory action a probiotic composition Bacillus subtilis B. megatherium strains (UnicaUro, Sirion (Ukraine)) for experimental bacterial vaginitis. Methods. Experimental studies were conducted on female BALB/c mice; we used Staphylococcus aureus strain B-918 (ATCC 6538) induce vaginally introduced into mice before treatment with bacteria. In vagina mice, aerobic optionally anaerobic bacteria, including representatives...
Оbjective.The objective of this study was to elucidate the effects probiotic strain Lactobacillus casei ІМV В-7280 and L. IMV B-7280 -Bifidobacterium animalis VKL -B.animalis VKB (Lc -VKL -VKB) or B. (VKL compositions that administrated both orally vaginally only orally, on vaginal microbiota cytokines production in experimental staphylococcosis BALB/c mice.Methods.Probiotic bacteria into staphylococcus-infected mice simulntaneously orally.Material from vagina plated selective media; number...
Проведено аналіз біосинтетичної активності рекомбінантного штаму Streptomyces recifensis DL-7 порівняно з вихідним штамом 2R-15. Отримані ацетонові препарати культуральної рідини двох штамів, здійснено фракціонування ферментів шляхом гельфільтрації. Встановлено, що показники літичної та протеолітичної значно вищі, ніж у вихідного
In modern clinical practice, the main methods for correcting elevated serum cholesterol levels are drugs that block activity of enzyme hydroxymethylglutaracyl-CoA-reductase (HMG-CoA-reductase) – statins or inhibit absorption and sterols in intestines ezetimibe. All hypocholesterolemic rather expensive have side effects, which is hepatotoxicity. During mono- combined therapy with HMG-CoA reductase inhibitors ezetimibe, cases increased alanine asparagine transaminases (biochemical indicator...
ЛАКТИТУ АБО ЛАКТУЛОЗИДосліджено вплив синбіотичних композицій пробіотичних штамів бацил та лактиту або лактулози на показники неспецифічного імунітету макроорганізму.Встановлено, що синбіотичні композиції основі пробіотичнихштамів Bacillus subtilis УКМ В-5139 B. В
The most common method of influenza prevention is intramuscular administration vaccines, which causes a higher antibody response than subcutaneous. However, such routes antigens result in the predominant formation serum IgG against viruses, while intranasal promotes titers both and IgA vaccination. Based on fact that this infectious agent enters body through mucous membranes respiratory tract, we developed concept local etiologically adequate vaccination, based statement vaccine should be...
Background. Development of new immunobiotics based on commensal nonpathogenic probiotic bacteria such as lactic acid and bifidobacteria with antibacterial immunomodulatory effects is an important area modern biotechnology.Оbjective. The aim this study was to determine the effect Lactobacillus acidophilus IMV B-7279, L. casei B-7280, delbrueckii subsp. bulgaricus ІМV В-7281, Bifidobacterium animalis VKL B. VKB (individually) or their different compositions number natural killer cells (NKC) in...
Probiotics based on bacteria of the genus Bacillus with a multifactorial mechanism action are considered as possible alternative to antibiotics in treatment purulent wounds. The aim study was determine antimicrobial and therapeutic effect Arederma probiotic preparation containing strains an experimental model wound animals. efficacy against test clinical isolates pathogenic opportunistic microorganisms studied using method delayed antagonism. Staphylococcus aureus ATCC 6538 Streptococcus...
Introduction. The use of probiotics demonstrate efficacy against obesity and metabolic syndrome (MetS). Detection effective probiotic strains for hyperglycemia immunity associated with is important task. aim the study was to evaluate an influence Lactobacillus casei IMV B-7280 separately composition L. / Bifidobacterium animalis VKB B. VKL on levels blood glucose in obese mice. Meterials methods. Obesity induced by fat-enriched diet (FED) male BALB/c Obese mice were transferred standard...
The objective of the study was determining prophylactic effect Lactobacillus casei IMV B-7280, L. acidophilus B-7279, delbrueckii subsp. bulgaricus B-7281, Bifidobacterium animalis VKL and B. VKB probiotic strains on experimental vaginitis in BALB/c mice induced by Staphylococcus aureus 8325-4. infection with S. 8325-4 caused an imbalance microbiota vagina intestine, as evidenced increase number opportunistic microorganisms a decrease amount lactobacilli bifidobacteria. altered spectrum...
The probiotic strains of Lactobacillus casei IMV B-7280, Bifidobacterium animalis VKL, B. VKB (individually) or L. B-7280 -B. VKL composition balanced the Th1/Th2 cytokines production at normal condition and in cases experimental intravaginal staphylococcosis BALB/c mice different periods observation. increased Th1 type interleukin (IL)-12 interferon (IFN)-γ production. Instead, after injection into intact did not affect IL-12 but slightly IFN-γ In balancing immune response under influence...
Cerium dioxide nanoparticles (CeO2) have a wide range of biological properties, including antiviral activity. Preparations based on cerium oxide can be effective against animal RNA viruses, which the greatest epizootic significance for Ukraine and potentially human SARS-CoV-2. In our studies, we determined effect bovine viral diarrhea virus (BVDV), pestivirus that is etiological agent diarrhea. To determine efficacy CeO2, cytopathogenic strain BVDV “BK-1” was used as an diarrhea, induces...